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Prodotti recenti

Antenatal diagnosis of beta-thalassemia in Sardinia

This paper reviews the characteristics and the results of 15 years of experience with a preventive program, based on carrier screening and prenatal diagnosis, designed to control thalassemia major in the Sardinian population. The education of the population about thalassemia and the mod...

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: I: Fetal risks

Objective: To assess fetal risk after pregnancy exposure to natalizumab in women with multiple sclerosis (MS), with a specific focus on spontaneous abortion (SA) and congenital anomalies (CA). Methods: Data of all pregnancies occurring between 2009 and 2015 in patients with MS treated&#...

The first mitogenome of the Cyprus mouflon (Ovis gmelini ophion): New insights into the phylogeny of the genus Ovis

Sheep are thought to have been one of the first livestock to be domesticated in the Near East, thus playing an important role in human history. The current whole mitochondrial genome phylogeny for the genus Ovis is based on: the five main domestic haplogroups occurring am...

A genetic association study of two genes linked to neurodegeneration in a Sardinian multiple sclerosis population: The TARDBP Ala382Thr mutation and C9orf72 expansion

Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by inflammation and accompanied and followed by neurodegeneration. Missense mutations of the TAR DNA Binding Protein gene (TARDBP) located in the chromosome 1p36.22 region, and the hexanucleotide repeat ...

Synthesis, characterization and study of luminescent Au/Ag and Au/Tl heterometallic compounds with mixed donor macrocyclic derivatives

Recently, compounds containing metallophilic interactions between gold (I) atoms and various metal ions having a "closed shell" electron configuration, [M = Cu(I), Ag(I), Tl(I), Pb(II), Hg(II), Bi(III), Sn(II)] have aroused considerable interest both in terms of theoretical aspects and their...

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