Sfoglia per Autore
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
2024-01-01 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication
2023-01-01 Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo
Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus
2023-01-01 Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon
Visible Light-Mediated Inactivation of H1N1 Virus UsingPolymer-Based Heterojunction Photocatalyst
2023-01-01 Porcu, Stefania; Maloccu, Stefania; Corona, Angela; Hazra, Moulika; David, TULLIA CARLA; Chiriu, Daniele; Carbonaro, CARLO MARIA; Tramontano, Enzo; Ricci, PIER CARLO
Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds
2023-01-01 Al Nasr, Ibrahim S; Corona, Angela; Koko, Waleed S; Khan, Tariq A; Ben Said, Ridha; Daoud, Ismail; Rahali, Seyfeddine; Tramontano, Enzo; Schobert, Rainer; Amdouni, Noureddine; Biersack, Bernhard
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023-01-01 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action
2023-01-01 Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M
Editorial: Viruses, innate immunity, and antiviral strategies: from basic research to clinical applications
2023-01-01 Fanunza, Elisa; Corona, Angela
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
2023-01-01 Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action
2023-01-01 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France)
2023-01-01 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
2023-01-01 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E.
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function
2023-01-01 Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca
Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication
2023-01-01 Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B.
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities
2022-01-01 Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production
2022-01-01 Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route
2022-01-01 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration
2022-01-01 Richetta, Clémence; Subra, Frédéric; Malet, Isabelle; Leh, Hervé; Charpentier, Charlotte; Corona, Angela; Collin, Gilles; Descamps, Diane; Deprez, Eric; Parissi, Vincent; Calvez, Vincent; Tramontano, Enzo; Marcelin, Anne-Geneviève; Delelis, Olivier
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
2022-01-01 Romeo, Isabella; Ambrosio, Francesca Alessandra; Costa, Giosuè; Corona, Angela; Alkhatib, Mohammad; Salpini, Romina; Lemme, Saverio; Vergni, Davide; Svicher, Valentina; Santoro, Maria Mercedes; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Artese, Anna; Alcaro, Stefano
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort
2022-01-01 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex | 1-gen-2024 | Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea | VIRUS RESEARCH | - |
| Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication | 1-gen-2023 | Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus | 1-gen-2023 | Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
| Visible Light-Mediated Inactivation of H1N1 Virus UsingPolymer-Based Heterojunction Photocatalyst | 1-gen-2023 | Porcu, Stefania; Maloccu, Stefania; Corona, Angela; Hazra, Moulika; David, TULLIA CARLA; Chiriu, Daniele; Carbonaro, CARLO MARIA; Tramontano, Enzo; Ricci, PIER CARLO | POLYMERS | - |
| Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds | 1-gen-2023 | Al Nasr, Ibrahim S; Corona, Angela; Koko, Waleed S; Khan, Tariq A; Ben Said, Ridha; Daoud, Ismail; Rahali, Seyfeddine; Tramontano, Enzo; Schobert, Rainer; Amdouni, Noureddine; Biersack, Bernhard | BIOORGANIC & MEDICINAL CHEMISTRY | - |
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1-gen-2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action | 1-gen-2023 | Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M | ANTIVIRAL RESEARCH | - |
| Editorial: Viruses, innate immunity, and antiviral strategies: from basic research to clinical applications | 1-gen-2023 | Fanunza, Elisa; Corona, Angela | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach | 1-gen-2023 | Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - |
| DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action | 1-gen-2023 | Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello | VIRUSES | - |
| HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) | 1-gen-2023 | Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca | PHARMACEUTICALS | - |
| 5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action | 1-gen-2023 | Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function | 1-gen-2023 | Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca | VIRUS RESEARCH | - |
| Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication | 1-gen-2023 | Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B. | VIRUSES | - |
| Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities | 1-gen-2022 | Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production | 1-gen-2022 | Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route | 1-gen-2022 | Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration | 1-gen-2022 | Richetta, Clémence; Subra, Frédéric; Malet, Isabelle; Leh, Hervé; Charpentier, Charlotte; Corona, Angela; Collin, Gilles; Descamps, Diane; Deprez, Eric; Parissi, Vincent; Calvez, Vincent; Tramontano, Enzo; Marcelin, Anne-Geneviève; Delelis, Olivier | JOURNAL OF VIROLOGY | - |
| Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach | 1-gen-2022 | Romeo, Isabella; Ambrosio, Francesca Alessandra; Costa, Giosuè; Corona, Angela; Alkhatib, Mohammad; Salpini, Romina; Lemme, Saverio; Vergni, Davide; Svicher, Valentina; Santoro, Maria Mercedes; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Artese, Anna; Alcaro, Stefano | MOLECULES | - |
| Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort | 1-gen-2022 | Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter | SCIENTIFIC DATA | - |
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