Sfoglia per Autore
Immune and glial cell alterations in the rat brain after repeated exposure to the synthetic cannabinoid JWH-018
2024-01-01 Pintori, Nicholas; Mostallino, Rafaela; Spano, Enrica; Orrù, Valeria; Piras, Maria Grazia; Castelli, Maria Paola; De Luca, Maria Antonietta
Regioselective synthesis of new EWG-Bearing 3-benzoyl-2-phenylbenzofurans by one-pot intramolecular acylation/thermal cyclization of phosphoranes and their CB1 antagonist activity
2024-01-01 Begala, Michela; Mancinelli, Michele; Mostallino, Rafaela; Castelli, MARIA PAOLA; Delogu, GIOVANNA LUCIA
Maternal immune activation impairs endocannabinoid signaling in the mesolimbic system of adolescent male offspring
2023-01-01 Santoni, Michele; Sagheddu, Claudia; Serra, Valeria; Mostallino, Rafaela; Paola Castelli, Maria; Pisano, Francesco; Scherma, Maria; Fadda, Paola; Muntoni, Anna Lisa; Zamberletti, Erica; Rubino, Tiziana; Melis, Miriam; Pistis, Marco
Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
2023-01-01 Margiani, Giulia; Castelli, Maria Paola; Pintori, Nicholas; Frau, Roberto; Ennas, Maria Grazia; Pagano Zottola, Antonio C.; Orrù, Valeria; Serra, Valentina; Fiorillo, Edoardo; Fadda, Paola; Marsicano, Giovanni; De Luca, Maria Antonietta
3‐[3‐(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone‐derived novel class of MOR‐antagonists
2022-01-01 Tocco, Graziella; Laus, Antonio; Vanejevs, Maksims; Ture, Anastasija; Mostallino, Rafaela; Pintori, Nicholas; De Luca, Maria Antonietta; Castelli, M. Paola; Di Chiara, Gaetano
Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
2022-01-01 Margiani, Giulia; Castelli, Maria Paola; Pintori, Nicholas; Frau, Roberto; Ennas, Maria Grazia; Orrù, Valeria; Serra, Valentina; Fiorillo, Edoardo; Fadda, Paola; Marsicano, Giovanni; De Luca, Maria Antonietta
Pharmacological characterization of novel synthetic opioids: Isotonitazene, metonitazene, and piperidylthiambutene as potent μ-opioid receptor agonists
2022-01-01 De Luca, Maria Antonietta; Tocco, Graziella; Mostallino, Rafaela; Laus, Antonio; Caria, Francesca; Musa, Aurora; Pintori, Nicholas; Ucha, Marcos; Poza, Celia; Ambrosio, Emilio; Di Chiara, Gaetano; Castelli, M Paola
Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopamine pathways, glial cells alteration and behavioural correlates
2021-01-01 Pintori, Nicholas; Castelli, Maria Paola; Miliano, Cristina; Simola, Nicola; Fadda, Paola; Fattore, Liana; Scherma, Maria; Ennas, Maria Grazia; Mostallino, Rafaela; Flore, Giovanna; De Felice, Marta; Sagheddu, Claudia; Pistis, Marco; Di Chiara, Gaetano; De Luca, Maria Antonietta
COR758, a negative allosteric modulator of GABAB receptors
2021-01-01 Porcu, A.; Mostallino, R.; Serra, V.; Melis, M.; Sogos, V.; Beggiato, S.; Ferraro, L.; Manetti, F.; Gianibbi, B.; Bettler, B.; Corelli, F.; Mugnaini, C.; Castelli, M. P.
Human neuronal cell lines as an in vitro toxicological tool for the evaluation of novel psychoactive substances
2021-01-01 Sogos, V.; Caria, P.; Porcedda, C.; Mostallino, R.; Piras, F.; Miliano, C.; De Luca, M. A.; Castelli, M. P.
Structure optimization of positive allosteric modulators of GABAB receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators
2020-01-01 Mugnaini, C.; Brizzi, A.; Mostallino, R.; Castelli, M. P.; Corelli, F.
Sex and gender differences in the effects of novel psychoactive substances
2020-01-01 Fattore, Liana; Marti, Matteo; Mostallino, Rafaela; Castelli, Maria Paola
The GABAB receptor positive allosteric modulator COR659: in vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives
2020-01-01 Ferlenghi, Francesca; Maccioni, Paola; Mugnaini, Claudia; Brizzi, Antonella; Fara, Federica; Mostallino, Rafaela; Castelli, Maria Paola; Colombo, Giancarlo; Mor, Marco; Vacondio, Federica; Corelli, Federico
Predisposition to alcohol drinking and alcohol consumption alter expression of calcitonin gene-related peptide, neuropeptide Y, and microglia in bed nucleus of stria terminalis in a subnucleus-specific manner
2019-01-01 Rossetti, Ilaria; Zambusi, Laura; Maccioni, Paola; Sau, Roberta; Provini, Luciano; Castelli, MARIA PAOLA; Gonciarz, Krzysztof; Colombo, Giancarlo; Morara, Stefano
Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe
2019-01-01 Miliano, Cristina; Marti, Matteo; Pintori, Nicholas; Castelli, Maria Paola; Tirri, Micaela; Arfè, Raffaella; De Luca, Maria Antonietta
Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa
2019-01-01 Collu, R.; Scherma, M.; Piscitelli, F.; Giunti, E.; Satta, V.; Castelli, M. P.; Verde, R.; Fratta, W.; Bisogno, T.; Fadda, P.
In vitro functional characterization of GET73 as possible negative allosteric modulator of metabotropic glutamate receptor 5
2018-01-01 Beggiato, Sarah; Borelli, Andrea C.; Tomasini, Maria C.; Castelli, MARIA PAOLA; Pintori, Nicholas; Cacciaglia, Roberto; Loche, Antonella; Ferraro, LUCA NICOLA
Limited access to a high fat diet alters endocannabinoid tone in female rats
2018-01-01 Satta, Valentina; Scherma, Maria; Piscitelli, Fabiana; Usai, Paolo; Castelli, M Paola; Bisogno, Tiziana; Fratta, Walter; Fadda, Paola
Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a G alpha(i/o) protein inhibitor
2018-01-01 Porcu, Alessandra; Melis, Miriam; Turecek, Rostislav; Ullrich, Celine; Mocci, Ignazia; Bettler, Bernhard; Luigi Gessa, Gian; Castelli, MARIA PAOLA
Suppressing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on chocolate self-administration and reinstatement of chocolate seeking in rats
2017-01-01 Lorrai, Irene; Maccioni, Paola; Carai, MAURO ANTONIO MARIA; Capra, Alessandro; Castelli, MARIA PAOLA; Riva, Antonella; Morazzoni, Paolo; Gessa, Gian Luigi; Colombo, Giancarlo
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Immune and glial cell alterations in the rat brain after repeated exposure to the synthetic cannabinoid JWH-018 | 1-gen-2024 | Pintori, Nicholas; Mostallino, Rafaela; Spano, Enrica; Orrù, Valeria; Piras, Maria Grazia; Castelli, Maria Paola; De Luca, Maria Antonietta | JOURNAL OF NEUROIMMUNOLOGY | - |
| Regioselective synthesis of new EWG-Bearing 3-benzoyl-2-phenylbenzofurans by one-pot intramolecular acylation/thermal cyclization of phosphoranes and their CB1 antagonist activity | 1-gen-2024 | Begala, Michela; Mancinelli, Michele; Mostallino, Rafaela; Castelli, MARIA PAOLA; Delogu, GIOVANNA LUCIA | TETRAHEDRON | - |
| Maternal immune activation impairs endocannabinoid signaling in the mesolimbic system of adolescent male offspring | 1-gen-2023 | Santoni, Michele; Sagheddu, Claudia; Serra, Valeria; Mostallino, Rafaela; Paola Castelli, Maria; Pisano, Francesco; Scherma, Maria; Fadda, Paola; Muntoni, Anna Lisa; Zamberletti, Erica; Rubino, Tiziana; Melis, Miriam; Pistis, Marco | BRAIN BEHAVIOR AND IMMUNITY | - |
| Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice | 1-gen-2023 | Margiani, Giulia; Castelli, Maria Paola; Pintori, Nicholas; Frau, Roberto; Ennas, Maria Grazia; Pagano Zottola, Antonio C.; Orrù, Valeria; Serra, Valentina; Fiorillo, Edoardo; Fadda, Paola; Marsicano, Giovanni; De Luca, Maria Antonietta | PSYCHOPHARMACOLOGY | - |
| 3‐[3‐(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone‐derived novel class of MOR‐antagonists | 1-gen-2022 | Tocco, Graziella; Laus, Antonio; Vanejevs, Maksims; Ture, Anastasija; Mostallino, Rafaela; Pintori, Nicholas; De Luca, Maria Antonietta; Castelli, M. Paola; Di Chiara, Gaetano | ARCHIV DER PHARMAZIE | - |
| Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice | 1-gen-2022 | Margiani, Giulia; Castelli, Maria Paola; Pintori, Nicholas; Frau, Roberto; Ennas, Maria Grazia; Orrù, Valeria; Serra, Valentina; Fiorillo, Edoardo; Fadda, Paola; Marsicano, Giovanni; De Luca, Maria Antonietta | PSYCHOPHARMACOLOGY | - |
| Pharmacological characterization of novel synthetic opioids: Isotonitazene, metonitazene, and piperidylthiambutene as potent μ-opioid receptor agonists | 1-gen-2022 | De Luca, Maria Antonietta; Tocco, Graziella; Mostallino, Rafaela; Laus, Antonio; Caria, Francesca; Musa, Aurora; Pintori, Nicholas; Ucha, Marcos; Poza, Celia; Ambrosio, Emilio; Di Chiara, Gaetano; Castelli, M Paola | NEUROPHARMACOLOGY | - |
| Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopamine pathways, glial cells alteration and behavioural correlates | 1-gen-2021 | Pintori, Nicholas; Castelli, Maria Paola; Miliano, Cristina; Simola, Nicola; Fadda, Paola; Fattore, Liana; Scherma, Maria; Ennas, Maria Grazia; Mostallino, Rafaela; Flore, Giovanna; De Felice, Marta; Sagheddu, Claudia; Pistis, Marco; Di Chiara, Gaetano; De Luca, Maria Antonietta | BRITISH JOURNAL OF PHARMACOLOGY | - |
| COR758, a negative allosteric modulator of GABAB receptors | 1-gen-2021 | Porcu, A.; Mostallino, R.; Serra, V.; Melis, M.; Sogos, V.; Beggiato, S.; Ferraro, L.; Manetti, F.; Gianibbi, B.; Bettler, B.; Corelli, F.; Mugnaini, C.; Castelli, M. P. | NEUROPHARMACOLOGY | - |
| Human neuronal cell lines as an in vitro toxicological tool for the evaluation of novel psychoactive substances | 1-gen-2021 | Sogos, V.; Caria, P.; Porcedda, C.; Mostallino, R.; Piras, F.; Miliano, C.; De Luca, M. A.; Castelli, M. P. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Structure optimization of positive allosteric modulators of GABAB receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators | 1-gen-2020 | Mugnaini, C.; Brizzi, A.; Mostallino, R.; Castelli, M. P.; Corelli, F. | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| Sex and gender differences in the effects of novel psychoactive substances | 1-gen-2020 | Fattore, Liana; Marti, Matteo; Mostallino, Rafaela; Castelli, Maria Paola | BRAIN SCIENCES | - |
| The GABAB receptor positive allosteric modulator COR659: in vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives | 1-gen-2020 | Ferlenghi, Francesca; Maccioni, Paola; Mugnaini, Claudia; Brizzi, Antonella; Fara, Federica; Mostallino, Rafaela; Castelli, Maria Paola; Colombo, Giancarlo; Mor, Marco; Vacondio, Federica; Corelli, Federico | EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | - |
| Predisposition to alcohol drinking and alcohol consumption alter expression of calcitonin gene-related peptide, neuropeptide Y, and microglia in bed nucleus of stria terminalis in a subnucleus-specific manner | 1-gen-2019 | Rossetti, Ilaria; Zambusi, Laura; Maccioni, Paola; Sau, Roberta; Provini, Luciano; Castelli, MARIA PAOLA; Gonciarz, Krzysztof; Colombo, Giancarlo; Morara, Stefano | FRONTIERS IN CELLULAR NEUROSCIENCE | - |
| Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe | 1-gen-2019 | Miliano, Cristina; Marti, Matteo; Pintori, Nicholas; Castelli, Maria Paola; Tirri, Micaela; Arfè, Raffaella; De Luca, Maria Antonietta | FRONTIERS IN PHARMACOLOGY | - |
| Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa | 1-gen-2019 | Collu, R.; Scherma, M.; Piscitelli, F.; Giunti, E.; Satta, V.; Castelli, M. P.; Verde, R.; Fratta, W.; Bisogno, T.; Fadda, P. | INTERNATIONAL JOURNAL OF EATING DISORDERS | - |
| In vitro functional characterization of GET73 as possible negative allosteric modulator of metabotropic glutamate receptor 5 | 1-gen-2018 | Beggiato, Sarah; Borelli, Andrea C.; Tomasini, Maria C.; Castelli, MARIA PAOLA; Pintori, Nicholas; Cacciaglia, Roberto; Loche, Antonella; Ferraro, LUCA NICOLA | FRONTIERS IN PHARMACOLOGY | - |
| Limited access to a high fat diet alters endocannabinoid tone in female rats | 1-gen-2018 | Satta, Valentina; Scherma, Maria; Piscitelli, Fabiana; Usai, Paolo; Castelli, M Paola; Bisogno, Tiziana; Fratta, Walter; Fadda, Paola | FRONTIERS IN NEUROSCIENCE | - |
| Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a G alpha(i/o) protein inhibitor | 1-gen-2018 | Porcu, Alessandra; Melis, Miriam; Turecek, Rostislav; Ullrich, Celine; Mocci, Ignazia; Bettler, Bernhard; Luigi Gessa, Gian; Castelli, MARIA PAOLA | NEUROPHARMACOLOGY | - |
| Suppressing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on chocolate self-administration and reinstatement of chocolate seeking in rats | 1-gen-2017 | Lorrai, Irene; Maccioni, Paola; Carai, MAURO ANTONIO MARIA; Capra, Alessandro; Castelli, MARIA PAOLA; Riva, Antonella; Morazzoni, Paolo; Gessa, Gian Luigi; Colombo, Giancarlo | NEUROSCIENCE LETTERS | - |
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