Sfoglia per Autore
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors
2013-01-01 Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Corona, Angela; Alcaro, S; Tramontano, Enzo
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT
2013-01-01 Bianco, Giulia; Distinto, Simona; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action
2013-01-01 Distinto, Simona; Bianco, Giulia; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor
2013-01-01 Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Maccioni, Elias; Le Grice, S.; Tramontano, Enzo
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT.
2013-01-01 Esposito, Francesca; Meleddu, R; Cannas, V; Distinto, Simona; Del Vecchio, C; Biano, G; Corona, Angela; Cottiglia, Filippo; Alcaro, S; Parolin, C; Maccioni, Elias; Tramontano, Enzo
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors
2012-01-01 Corona, Angela; Meleddu, R.; Esposito, Francesca; Sanna, M. L.; Distinto, Simona; Maccioni, Elias; Tramontano, Enzo
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions
2012-01-01 Tramontano, Enzo; Meleddu, R.; Corona, Angela; Distinto, Simona; Esposito, Francesca; Cannas, V.; Alcaro, S.; Costa, G.; Ortuso, F.; Maccioni, Elias
9-fluorenones as new scaffolds for G-quadruplex DNA
2012-01-01 Meleddu, R.; Distinto, Simona; Parrotta, L.; Maccioni, Elias; Musetti, C.; Sissi, C; Sanna, M. L.; Alcaro, S.
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders
2012-01-01 Alcaro, S.; Maccioni, Elias; Distinto, Simona; Parrotta, L.; Meleddu, R.; Artese, A.; Moraca, F.; Musetti, C.; Sissi, C.
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach
2012-01-01 Distinto, Simona; Esposito, Francesca; Kirchmair, J; Cardia, MARIA CRISTINA; Gaspari, M; Maccioni, Elias; Alcaro, S; Markt, P; Wolber, G; Zinzula, Luca; Tramontano, Enzo
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B
2012-01-01 Distinto, Simona; Yáñez, M; Alcaro, S; Cardia, MARIA CRISTINA; Gaspari, M; Sanna, MARIA LUISA; Meleddu, Rita; Ortuso, F; Kirchmair, J; Markt, P; Bolasco, A; Wolber, G; Secci, D; Maccioni, Elias
Discovery and optimization of pyrazoline derivatives as promising monoamine oxidase inhibitors
2012-01-01 Secci, Daniela; Carradori, Simone; Bolasco, Adriana; Bizzarri, Bruna; D'Ascenzio, Melissa; Maccioni, Elias
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS
2012-01-01 Corona, Angela; Meleddu, R.; Esposito, Francesca; Distinto, S.; Maccioni, Elias; Tramontano, S. Le Griceand E.
From classic to innovative approaches in HIV-1 infection treatment
2012-01-01 Maccioni, Elias; Distinto, Simona; Alcaro, S.; Meleddu, R.; Esposito, Francesca; Corona, Angela; Sanna, M. L.; Tramontano, Enzo
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors
2011-01-01 Meleddu, R.; Corona, Angela; Distinto, Simona; Sanna, M. L.; Esposito, Francesca; Cardia, M. C.; Tramontano, Enzo; Maccioni, Elias
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function
2011-01-01 Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias
Identification of HIV-1 reverse trascriptase dual inhibitors by a combined shape-, 2D fingerprint and pharmacophore-based virtual screening approch
2011-01-01 Distinto, S.; Esposito, E.; Kirchmair, J.; Cardia, MARIA CRISTINA; Maccioni, Elias; Alcaro, S.; Zinzula, L; Tramontano, Enzo
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1
2011-01-01 Meleddu, R.; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase
2011-01-01 Meleddu, Rita; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Distinto, Simona; Sanna, M. L.; Cardia, C.; Alcaro, S.; Maccioni, Elias
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey
2011-01-01 Dunkel, P; Balogh, B; Meleddu, Rita; Maccioni, Elias; Gyires, K; Mátyus, P.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors | 1-gen-2013 | Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Corona, Angela; Alcaro, S; Tramontano, Enzo | CURRENT PHARMACEUTICAL DESIGN | - |
| Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT | 1-gen-2013 | Bianco, Giulia; Distinto, Simona; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action | 1-gen-2013 | Distinto, Simona; Bianco, Giulia; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor | 1-gen-2013 | Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Maccioni, Elias; Le Grice, S.; Tramontano, Enzo | RETROVIROLOGY | BioMed Central Ltd |
| Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. | 1-gen-2013 | Esposito, Francesca; Meleddu, R; Cannas, V; Distinto, Simona; Del Vecchio, C; Biano, G; Corona, Angela; Cottiglia, Filippo; Alcaro, S; Parolin, C; Maccioni, Elias; Tramontano, Enzo | - | - |
| Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors | 1-gen-2012 | Corona, Angela; Meleddu, R.; Esposito, Francesca; Sanna, M. L.; Distinto, Simona; Maccioni, Elias; Tramontano, Enzo | - | - |
| Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions | 1-gen-2012 | Tramontano, Enzo; Meleddu, R.; Corona, Angela; Distinto, Simona; Esposito, Francesca; Cannas, V.; Alcaro, S.; Costa, G.; Ortuso, F.; Maccioni, Elias | - | - |
| 9-fluorenones as new scaffolds for G-quadruplex DNA | 1-gen-2012 | Meleddu, R.; Distinto, Simona; Parrotta, L.; Maccioni, Elias; Musetti, C.; Sissi, C; Sanna, M. L.; Alcaro, S. | - | - |
| Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders | 1-gen-2012 | Alcaro, S.; Maccioni, Elias; Distinto, Simona; Parrotta, L.; Meleddu, R.; Artese, A.; Moraca, F.; Musetti, C.; Sissi, C. | - | - |
| Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach | 1-gen-2012 | Distinto, Simona; Esposito, Francesca; Kirchmair, J; Cardia, MARIA CRISTINA; Gaspari, M; Maccioni, Elias; Alcaro, S; Markt, P; Wolber, G; Zinzula, Luca; Tramontano, Enzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B | 1-gen-2012 | Distinto, Simona; Yáñez, M; Alcaro, S; Cardia, MARIA CRISTINA; Gaspari, M; Sanna, MARIA LUISA; Meleddu, Rita; Ortuso, F; Kirchmair, J; Markt, P; Bolasco, A; Wolber, G; Secci, D; Maccioni, Elias | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Discovery and optimization of pyrazoline derivatives as promising monoamine oxidase inhibitors | 1-gen-2012 | Secci, Daniela; Carradori, Simone; Bolasco, Adriana; Bizzarri, Bruna; D'Ascenzio, Melissa; Maccioni, Elias | CURRENT TOPICS IN MEDICINAL CHEMISTRY | - |
| SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS | 1-gen-2012 | Corona, Angela; Meleddu, R.; Esposito, Francesca; Distinto, S.; Maccioni, Elias; Tramontano, S. Le Griceand E. | - | - |
| From classic to innovative approaches in HIV-1 infection treatment | 1-gen-2012 | Maccioni, Elias; Distinto, Simona; Alcaro, S.; Meleddu, R.; Esposito, Francesca; Corona, Angela; Sanna, M. L.; Tramontano, Enzo | - | - |
| Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors | 1-gen-2011 | Meleddu, R.; Corona, Angela; Distinto, Simona; Sanna, M. L.; Esposito, Francesca; Cardia, M. C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| 3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function | 1-gen-2011 | Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| Identification of HIV-1 reverse trascriptase dual inhibitors by a combined shape-, 2D fingerprint and pharmacophore-based virtual screening approch | 1-gen-2011 | Distinto, S.; Esposito, E.; Kirchmair, J.; Cardia, MARIA CRISTINA; Maccioni, Elias; Alcaro, S.; Zinzula, L; Tramontano, Enzo | - | - |
| Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 | 1-gen-2011 | Meleddu, R.; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase | 1-gen-2011 | Meleddu, Rita; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Distinto, Simona; Sanna, M. L.; Cardia, C.; Alcaro, S.; Maccioni, Elias | - | - |
| Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey | 1-gen-2011 | Dunkel, P; Balogh, B; Meleddu, Rita; Maccioni, Elias; Gyires, K; Mátyus, P. | EXPERT OPINION ON THERAPEUTIC PATENTS | - |
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