SABA, PIERLUIGI
SABA, PIERLUIGI
DIPARTIMENTO DI SCIENZE BIOMEDICHE
Combined α2- and D2-receptor blockade activates noradrenergic and dopaminergic neurons, but extracellular dopamine in the prefrontal cortex is determined by uptake and release from noradrenergic terminals
2023-01-01 Sagheddu, Claudia; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi
The potent α2-adrenoceptor antagonist RS 79948 also inhibits dopamine D2 -receptors: Comparison with atipamezole and raclopride
2022-01-01 Frau, Roberto; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Sagheddu, Claudia; Siddi, Carlotta; Santoni, Michele; Carli, Marco; Gessa, Gian Luigi
Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats
2021-01-01 Traccis, Francesco; Serra, Valeria; Sagheddu, Claudia; Congiu, Mauro; Saba, Pierluigi; Giua, Gabriele; Devoto, Paola; Frau, Roberto; Cheer, Joseph Francois; Melis, Miriam
Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex
2020-01-01 Devoto, Paola; Sagheddu, Claudia; Santoni, Michele; Flore, Giovanna; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi
Noradrenergic terminals are the primary source of α2-adrenoceptor mediated dopamine release in the medial prefrontal cortex
2019-01-01 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Scheggi, Simona; Mulas, Giovanna; Gambarana, Carla; Spiga, Saturnino; Gessa, Gian Luigi
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
2019-01-01 Frau, Roberto; Miczán, Vivien; Traccis, Francesco; Aroni, Sonia; Pongor, Csaba I; Saba, Pierluigi; Serra, Valeria; Sagheddu, Claudia; Fanni, Silvia; Congiu, Mauro; Devoto, Paola; Cheer, JOSEPH FRANCOIS RENE; Katona, Istvan; Melis, Miriam
Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex
2018-01-01 Antinori, Silvia; Fattore, Liana; Saba, Pierluigi; Fratta, Walter; Gessa, Gian Luigi; Devoto, Paola
Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation
2016-01-01 Devoto, Paola; Fattore, L; Antinori, Silvia; Saba, Pierluigi; Frau, Roberto; Fratta, Walter; Gessa, Gl
The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating
2016-01-01 Frau, Roberto; Mosher, Lj; Bini, Valentina; Pillolla, Giuliano; Pes, Romina; Saba, Pierluigi; Fanni, Silvia; Devoto, Paola; Bortolato, M.
Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex
2015-01-01 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Frau, Roberto; Gessa, Gian L.
Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation
2014-01-01 Frau, Roberto; Bini, V; Pes, Romina; Pillolla, Giuliano; Saba, Pierluigi; Devoto, Paola; Bortolato, M.
The dopamine beta-hydroxylase inhibitor nepicastat increases dopamine release and potentiates psychostimulant-induced dopamine release in the prefrontal cortex
2014-01-01 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Bini, Valentina; Gessa, Gl
Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex
2012-01-01 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Cadeddu, Roberto; Gessa, Gl
Inhibition of 5 alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
2012-01-01 Devoto, Paola; Frau, Roberto; Bini, V; Pillolla, Giuliano; Saba, Pierluigi; Flore, Giovanna; Corona, M; Marrosu, Francesco; Bortolato, M.
Isolation rearing-induced reduction of brain 5 alpha-reductase expression: Relevance to dopaminergic impairments
2011-01-01 Bortolato, M; Devoto, Paola; Roncada, P; Frau, Roberto; Flore, G; Saba, Pierluigi; Pistritto, G; Soggiu, A; Pisanu, S; Zappala, A; Ristaldi, Ms; Tattoli, M; Cuomo, V; Marrosu, Francesco; Barbaccia, Ml
Inhibition of 5-alpha reductase elicits antipsychotic-like effects via post-synaptic mechanisms in nucleus accumbens and prefrontal cortex
2010-01-01 Frau, Roberto; Bini, V; Pillola, G; Saba, Pierluigi; Bortolato, M; Devoto, Paola
Effects of post-weaning social isolation on 5-alpha reductase: Relevance to dopaminergic pathway
2009-01-01 Bortolato, M; Frau, Roberto; Bini, V; Flore, G; Paba, S; Saba, Pierluigi; Marrosu, Francesco; Ristaldi, Ms; Roncada, P; Devoto, Paola
Gating deficits in isolation-reared rats are correlated with alterations in protein expression in nucleus accumbens
2009-01-01 Roncada, P; Bortolato, M; Frau, Roberto; Saba, Pierluigi; Flore, G; Soggiu, A; Pisanu, S; Amoresano, A; Carpentieri, A; Devoto, Paola
6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex
2008-01-01 Devoto, Paola; Flore, G; Saba, Pierluigi; Castelli, MARIA PAOLA; Piras, Ap; Luesu, William; Viaggi, Mc; Ennas, MARIA GRAZIA; Gessa, Gl
Altered expression level of nucleus accumbens proteins in isolation-reared rats
2008-01-01 Devoto, Paola; Saba, Pierluigi; Bortolato, M; Frau, Roberto; Flore, G; Soggiu, A; Pisanu, S; Amoresano, A; Carpentieri, A; Roncada, P.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Combined α2- and D2-receptor blockade activates noradrenergic and dopaminergic neurons, but extracellular dopamine in the prefrontal cortex is determined by uptake and release from noradrenergic terminals | 1-gen-2023 | Sagheddu, Claudia; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi | FRONTIERS IN PHARMACOLOGY | - |
| The potent α2-adrenoceptor antagonist RS 79948 also inhibits dopamine D2 -receptors: Comparison with atipamezole and raclopride | 1-gen-2022 | Frau, Roberto; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Sagheddu, Claudia; Siddi, Carlotta; Santoni, Michele; Carli, Marco; Gessa, Gian Luigi | NEUROPHARMACOLOGY | - |
| Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats | 1-gen-2021 | Traccis, Francesco; Serra, Valeria; Sagheddu, Claudia; Congiu, Mauro; Saba, Pierluigi; Giua, Gabriele; Devoto, Paola; Frau, Roberto; Cheer, Joseph Francois; Melis, Miriam | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex | 1-gen-2020 | Devoto, Paola; Sagheddu, Claudia; Santoni, Michele; Flore, Giovanna; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi | FRONTIERS IN PHARMACOLOGY | - |
| Noradrenergic terminals are the primary source of α2-adrenoceptor mediated dopamine release in the medial prefrontal cortex | 1-gen-2019 | Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Scheggi, Simona; Mulas, Giovanna; Gambarana, Carla; Spiga, Saturnino; Gessa, Gian Luigi | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | - |
| Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone | 1-gen-2019 | Frau, Roberto; Miczán, Vivien; Traccis, Francesco; Aroni, Sonia; Pongor, Csaba I; Saba, Pierluigi; Serra, Valeria; Sagheddu, Claudia; Fanni, Silvia; Congiu, Mauro; Devoto, Paola; Cheer, JOSEPH FRANCOIS RENE; Katona, Istvan; Melis, Miriam | NATURE NEUROSCIENCE | - |
| Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex | 1-gen-2018 | Antinori, Silvia; Fattore, Liana; Saba, Pierluigi; Fratta, Walter; Gessa, Gian Luigi; Devoto, Paola | ADDICTION BIOLOGY | - |
| Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation | 1-gen-2016 | Devoto, Paola; Fattore, L; Antinori, Silvia; Saba, Pierluigi; Frau, Roberto; Fratta, Walter; Gessa, Gl | ADDICTION BIOLOGY | - |
| The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating | 1-gen-2016 | Frau, Roberto; Mosher, Lj; Bini, Valentina; Pillolla, Giuliano; Pes, Romina; Saba, Pierluigi; Fanni, Silvia; Devoto, Paola; Bortolato, M. | PSYCHONEUROENDOCRINOLOGY | - |
| Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex | 1-gen-2015 | Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Frau, Roberto; Gessa, Gian L. | BRAIN AND BEHAVIOR | - |
| Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation | 1-gen-2014 | Frau, Roberto; Bini, V; Pes, Romina; Pillolla, Giuliano; Saba, Pierluigi; Devoto, Paola; Bortolato, M. | PSYCHONEUROENDOCRINOLOGY | - |
| The dopamine beta-hydroxylase inhibitor nepicastat increases dopamine release and potentiates psychostimulant-induced dopamine release in the prefrontal cortex | 1-gen-2014 | Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Bini, Valentina; Gessa, Gl | ADDICTION BIOLOGY | - |
| Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex | 1-gen-2012 | Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Cadeddu, Roberto; Gessa, Gl | PSYCHOPHARMACOLOGY | - |
| Inhibition of 5 alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation | 1-gen-2012 | Devoto, Paola; Frau, Roberto; Bini, V; Pillolla, Giuliano; Saba, Pierluigi; Flore, Giovanna; Corona, M; Marrosu, Francesco; Bortolato, M. | PSYCHONEUROENDOCRINOLOGY | - |
| Isolation rearing-induced reduction of brain 5 alpha-reductase expression: Relevance to dopaminergic impairments | 1-gen-2011 | Bortolato, M; Devoto, Paola; Roncada, P; Frau, Roberto; Flore, G; Saba, Pierluigi; Pistritto, G; Soggiu, A; Pisanu, S; Zappala, A; Ristaldi, Ms; Tattoli, M; Cuomo, V; Marrosu, Francesco; Barbaccia, Ml | NEUROPHARMACOLOGY | - |
| Inhibition of 5-alpha reductase elicits antipsychotic-like effects via post-synaptic mechanisms in nucleus accumbens and prefrontal cortex | 1-gen-2010 | Frau, Roberto; Bini, V; Pillola, G; Saba, Pierluigi; Bortolato, M; Devoto, Paola | - | 40th Annual Meeting of Society of Neuroscience |
| Effects of post-weaning social isolation on 5-alpha reductase: Relevance to dopaminergic pathway | 1-gen-2009 | Bortolato, M; Frau, Roberto; Bini, V; Flore, G; Paba, S; Saba, Pierluigi; Marrosu, Francesco; Ristaldi, Ms; Roncada, P; Devoto, Paola | SOCIETY FOR NEUROSCIENCE | - |
| Gating deficits in isolation-reared rats are correlated with alterations in protein expression in nucleus accumbens | 1-gen-2009 | Roncada, P; Bortolato, M; Frau, Roberto; Saba, Pierluigi; Flore, G; Soggiu, A; Pisanu, S; Amoresano, A; Carpentieri, A; Devoto, Paola | JOURNAL OF NEUROCHEMISTRY | - |
| 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex | 1-gen-2008 | Devoto, Paola; Flore, G; Saba, Pierluigi; Castelli, MARIA PAOLA; Piras, Ap; Luesu, William; Viaggi, Mc; Ennas, MARIA GRAZIA; Gessa, Gl | JOURNAL OF NEUROSCIENCE RESEARCH | - |
| Altered expression level of nucleus accumbens proteins in isolation-reared rats | 1-gen-2008 | Devoto, Paola; Saba, Pierluigi; Bortolato, M; Frau, Roberto; Flore, G; Soggiu, A; Pisanu, S; Amoresano, A; Carpentieri, A; Roncada, P. | SOCIETY FOR NEUROSCIENCE | SFN |