COLUMBANO, AMEDEO
COLUMBANO, AMEDEO
DIPARTIMENTO DI SCIENZE BIOMEDICHE
Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes
2024-01-01 Kowalik, M. A.; Taguchi, K.; Serra, M.; Caddeo, A.; Puliga, E.; Bacci, M.; Koshiba, S.; Inoue, J.; Hishinuma, E.; Morandi, A.; Giordano, S.; Perra, A.; Yamamoto, M.; Columbano, A.
Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis
2023-01-01 Caddeo, A.; Serra, M.; Sedda, F.; Bacci, A.; Manera, C.; Rapposelli, S.; Columbano, A.; Perra, A.; Kowalik, M. A.
Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development
2022-01-01 Serra, Marina; Di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Cafarello, Sarah Trusso; Lanza, Martina; Sanchez-Martin, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego Francesco; Mazzone, Massimiliano; Columbano, Amedeo
Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia
2022-01-01 Pal, Rajesh; Kowalik, MARTA ANNA; Serra, Marina; Migliore, Cristina; Giordano, Silvia; Columbano, Amedeo; Perra, Andrea
INHIBITORY EFFECT OF LDHA KNOCK-OUT ON METABOLIC REPROGRAMMING IN C-MYC/H-RAS DRIVEN HEPATOCELLULAR CARCINOMA
2022-01-01 Serra, Marina; di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Trusso Cafarello, Sarah; Lanza, Martina; Sanchez-Martin, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego; Mazzone, Massimiliano; Columbano, Amedeo
Metabolic alterations of HCC are dependent upon different oncogene activation
2022-01-01 Serra, Marina; di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Trusso Cafarello, Sarah; Lanza, Martina; Sanchez-Martina, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego; Mazzone, Massimiliano; Columbano, Amedeo
mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma
2022-01-01 Serra, Marina; Pal, Rajesh; Puliga, Elisabetta; Sulas, Pia; Cabras, Lavinia; Cusano, Roberto; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo; Kowalik, Marta Anna
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC
2022-01-01 Mattu, Sandra; Zavattari, Patrizia; Kowalik, Marta Anna; Serra, Marina; Sulas, Pia; Pal, Rajesh; Puliga, Elisabetta; Sutti, Salvatore; Foglia, Beatrice; Parola, Maurizio; Albano, Emanuele; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo
Oncogene-dependent HCC metabolic reprogramming
2022-01-01 Serra, Marina; Di Matteo, M.; Serneels, J.; Pal, R.; Trusso Cafarello, S.; Lanza, M.; Sanchez-Martin, C.; Evert, M.; Castegna, A.; Calvisi, D. F.; Mazzone, Massimiliano; Columbano, Amedeo
INIBITORY EFFECT OF LDHA KNOCK-DOWN ON METABOLIC REPROGRAMMING AND C-MYC/H-RAS DRIVEN HEPATOCELLULAR CARCINOMA
2021-01-01 Serra, Marina; di Matteo, Mario; Mazzone, Massimiliano; Columbano, Amedeo
METABOLIC REPROGRAMMING IN A C-MYC/H-RAS TRANSGENIC MOUSE MODEL OF HEPATOCELLULAR CARCINOMA
2021-01-01 Serra, Marina; di Matteo, Mario; Mazzone, Massimiliano; Columbano, Amedeo
Novel thyroid hormone receptor beta agonist TG68 safely induces hepatic fat loss reduction in a NASH mouse model
2021-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Tg68, a novel thyroid hormone receptor‐β agonist for the treatment of NAFLD
2021-01-01 Caddeo, A.; Kowalik, M. A.; Serra, M.; Runfola, M.; Bacci, A.; Rapposelli, S.; Columbano, A.; Perra, A.
Animal models: A useful tool to unveil metabolic changes in hepatocellular carcinoma
2020-01-01 Serra, M.; Columbano, A.; Perra, A.; Kowalik, M. A.
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
2020-01-01 Runfola, M.; Sestito, S.; Bellusci, L.; La Pietra, V.; D'Amore, V. M.; Kowalik, M. A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S.
Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis
2020-01-01 Orrù, Claudia; Perra, Andrea; Kowalik, Marta Anna; Rizzolio, Sabrina; Puliga, Elisabetta; Cabras, Lavinia; Giordano, Silvia; Columbano, Amedeo
Nrf2 in neoplastic and non-neoplastic liver diseases
2020-01-01 Orru, C.; Giordano, S.; Columbano, A.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes | 1-gen-2024 | Kowalik, M. A.; Taguchi, K.; Serra, M.; Caddeo, A.; Puliga, E.; Bacci, M.; Koshiba, S.; Inoue, J.; Hishinuma, E.; Morandi, A.; Giordano, S.; Perra, A.; Yamamoto, M.; Columbano, A. | HEPATOLOGY | - |
| Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis | 1-gen-2023 | Caddeo, A.; Serra, M.; Sedda, F.; Bacci, A.; Manera, C.; Rapposelli, S.; Columbano, A.; Perra, A.; Kowalik, M. A. | FRONTIERS IN ONCOLOGY | - |
| Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development | 1-gen-2022 | Serra, Marina; Di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Cafarello, Sarah Trusso; Lanza, Martina; Sanchez-Martin, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego Francesco; Mazzone, Massimiliano; Columbano, Amedeo | CMGH | - |
| Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia | 1-gen-2022 | Pal, Rajesh; Kowalik, MARTA ANNA; Serra, Marina; Migliore, Cristina; Giordano, Silvia; Columbano, Amedeo; Perra, Andrea | CELL PROLIFERATION | - |
| INHIBITORY EFFECT OF LDHA KNOCK-OUT ON METABOLIC REPROGRAMMING IN C-MYC/H-RAS DRIVEN HEPATOCELLULAR CARCINOMA | 1-gen-2022 | Serra, Marina; di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Trusso Cafarello, Sarah; Lanza, Martina; Sanchez-Martin, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego; Mazzone, Massimiliano; Columbano, Amedeo | - | - |
| Metabolic alterations of HCC are dependent upon different oncogene activation | 1-gen-2022 | Serra, Marina; di Matteo, Mario; Serneels, Jens; Pal, Rajesh; Trusso Cafarello, Sarah; Lanza, Martina; Sanchez-Martina, Carlos; Evert, Matthias; Castegna, Alessandra; Calvisi, Diego; Mazzone, Massimiliano; Columbano, Amedeo | - | - |
| mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma | 1-gen-2022 | Serra, Marina; Pal, Rajesh; Puliga, Elisabetta; Sulas, Pia; Cabras, Lavinia; Cusano, Roberto; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo; Kowalik, Marta Anna | FRONTIERS IN ONCOLOGY | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC | 1-gen-2022 | Mattu, Sandra; Zavattari, Patrizia; Kowalik, Marta Anna; Serra, Marina; Sulas, Pia; Pal, Rajesh; Puliga, Elisabetta; Sutti, Salvatore; Foglia, Beatrice; Parola, Maurizio; Albano, Emanuele; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo | CMGH | - |
| Oncogene-dependent HCC metabolic reprogramming | 1-gen-2022 | Serra, Marina; Di Matteo, M.; Serneels, J.; Pal, R.; Trusso Cafarello, S.; Lanza, M.; Sanchez-Martin, C.; Evert, M.; Castegna, A.; Calvisi, D. F.; Mazzone, Massimiliano; Columbano, Amedeo | - | - |
| INIBITORY EFFECT OF LDHA KNOCK-DOWN ON METABOLIC REPROGRAMMING AND C-MYC/H-RAS DRIVEN HEPATOCELLULAR CARCINOMA | 1-gen-2021 | Serra, Marina; di Matteo, Mario; Mazzone, Massimiliano; Columbano, Amedeo | - | - |
| METABOLIC REPROGRAMMING IN A C-MYC/H-RAS TRANSGENIC MOUSE MODEL OF HEPATOCELLULAR CARCINOMA | 1-gen-2021 | Serra, Marina; di Matteo, Mario; Mazzone, Massimiliano; Columbano, Amedeo | - | - |
| Novel thyroid hormone receptor beta agonist TG68 safely induces hepatic fat loss reduction in a NASH mouse model | 1-gen-2021 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Tg68, a novel thyroid hormone receptor‐β agonist for the treatment of NAFLD | 1-gen-2021 | Caddeo, A.; Kowalik, M. A.; Serra, M.; Runfola, M.; Bacci, A.; Rapposelli, S.; Columbano, A.; Perra, A. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Animal models: A useful tool to unveil metabolic changes in hepatocellular carcinoma | 1-gen-2020 | Serra, M.; Columbano, A.; Perra, A.; Kowalik, M. A. | CANCERS | - |
| Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis | 1-gen-2020 | Runfola, M.; Sestito, S.; Bellusci, L.; La Pietra, V.; D'Amore, V. M.; Kowalik, M. A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis | 1-gen-2020 | Orrù, Claudia; Perra, Andrea; Kowalik, Marta Anna; Rizzolio, Sabrina; Puliga, Elisabetta; Cabras, Lavinia; Giordano, Silvia; Columbano, Amedeo | CANCERS | - |
| Nrf2 in neoplastic and non-neoplastic liver diseases | 1-gen-2020 | Orru, C.; Giordano, S.; Columbano, A. | CANCERS | - |