DISTINTO, SIMONA

DISTINTO, SIMONA  

DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE  

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Risultati 1 - 20 di 134 (tempo di esecuzione: 0.066 secondi).
Titolo Data di pubblicazione Autore(i) Rivista Editore
1-acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 1-gen-2008 Vigo, S.; Alcaro, S.; Bolasco, A.; Cardia, C.; Distinto, Simona; Maccioni, Elias; Orallo, F.; Ortuso, F.; Sanna, M. L.; Secci, D.; Yanez, M. - -
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 1-gen-2008 Sanna, M. L.; Alcaro, S.; Bolasco, A.; Cardia, C.; Cirilli, R.; Distinto, Simona; Maccioni, Elias; Orallo, F.; Ortuso, F.; Secci, D.; Vigo, S.; Yanez, M. - -
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 1-gen-2013 Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; DE LOGU, Alessandro; Matyus, P.; Maccioni, Elias - -
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 1-gen-2021 Oliveira, D.; Borges, A.; Ruiz, R. M.; Negrin, Z. R.; Distinto, S.; Borges, F.; Simoes, M. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES -
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1-gen-2014 Corona, Angela; Meleddu, R.; Esposito, E.; Distinto, S.; Bianco, G.; Maccioni, E.; Tramontano, E. . - -
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 1-gen-2011 Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias - -
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 1-gen-2011 Maccioni, Elias; Alcaro, S.; Cirilli, R.; Vigo, S.; Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; Meleddu, Rita; Yanez, M.; Costa, G.; Casu, Laura; Matyus, P.; Distinto, Simona JOURNAL OF MEDICINAL CHEMISTRY -
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 1-gen-2015 Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
9-fluorenones as new scaffolds for G-quadruplex DNA 1-gen-2012 Meleddu, R.; Distinto, Simona; Parrotta, L.; Maccioni, Elias; Musetti, C.; Sissi, C; Sanna, M. L.; Alcaro, S. - -
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1-gen-2011 Esposito, Francesca; Distinto, Simona; J., Kirchmair; C. M., Cardia; Maccioni, Elias; S., Alcaro; L., Zinzula; E., Tramontano - -
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1-gen-2010 Esposito, F.; Kharlamova, T.; Distinto, S.; Zinzula, L.; Cheng, Y-C.; Dutschman, G.; Floris, G.; Markt, P.; Tramontano, E. - -
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1-gen-2010 Esposito, F; Kharlamova, T.; Distinto, S.; Zinzula, L.; Floris, G.; Sanna Randaccio, L.; Deutschman, G.; Cheng, Y-C.; Tramontano, E. - -
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1-gen-2011 Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo THE FEBS JOURNAL -
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 1-gen-2011 Meleddu, Rita; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Distinto, Simona; Sanna, M. L.; Cardia, C.; Alcaro, S.; Maccioni, Elias - -
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 1-gen-2008 Distinto, Simona; Maccioni, Elias; Alcaro, S.; Orallo, F.; Wolber, G.; Cardia, M. C.; Secci, D.; Bolasco, A.; Ortuso, F.; Sanna, M. L.; Vigo, S.; Yanez, M.; Kirchmair, J.; Markt, P.; Chimenti, F. - -
CoMFA studies of non-covalent monoamine oxidase inhibitors 1-gen-2007 Distinto, Simona; Maccioni, Elias; Cardia, M. C.; Sanna, M. L.; Alcaro, S.; Ortuso, F.; Artese, A.; Chimenti, F.; Secci, D.; Bolasco, A.; Orallo, F.; Kirchmair, J.; Langer, T. - -
COMP 266-The performance of 3-D shape-based virtual screening is not necessarily related to the quality of the query conformation 1-gen-2008 Kirchmair, J.; Distinto, Simona; Markt, P.; Schuster, D.; Spitzer, G. M.; Liedl, K. R.; Wolber, G. ABSTRACTS OF PAPERS - AMERICAN CHEMICAL SOCIETY -
COMP389-Successful application of a combined 3D pharmacophore, 3D shape, and electrostatic similarity virtual screening workflow to discover novel PPAR agonists 1-gen-2008 Markt, P.; Petersen, R. K.; Flindt, E. N.; Krjstiansen, K.; Kirchmair, J.; Spitzer, G.; Distinto, Simona; Schuster, D.; Wolber, G.; Laggner, C.; Langer, T. - -
Computational and experimental study of non-covalent monoamine oxidase inhibitors 1-gen-2007 Distinto, Simona; Maccioni, Elias; Cardia, M. C.; Sanna, M. L.; Alcaro, S.; Ortuso, F.; Chimenti, F.; Secci, D.; Bolasco, A.; Orallo, F.; Langer, T. - -
Computational approaches for discovery and optimization of G-quadruplex binders 1-gen-2009 Distinto, Simona; Alcaro, S.; Artese, A.; Costa, G.; Ortuso, F.; Parrotta, L. - -