DEMURU, LAURA
DEMURU, LAURA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
A combination of MD-derived pharmacophores and structure-based strategy identifies dual allosteric inhibitors of NS2B-NS3 proteases in Zika and West Nile viruses
2026-01-01 Lupia, Antonio; Nieddu, Salvatore; Demuru, Laura; Sanna, Erica; Onali, Alessia; Emmolo, Roberta; Malune, Paolo; Distinto, Simona; Atzeni, Giulia; Paulis, Annalaura; Meleddu, Rita; Cottiglia, Filippo; Esposito, Francesca; Corona, Angela; Bryant, Sharon D.; Maccioni, Elias; Tramontano, Enzo
Structure-based virtual screening leads to the discovery of a 4,5-dihydropyrazole derivative as the first dual inhibitor of West Nile virus NS3 helicase and protease
2026-01-01 Lupia, Antonio; Emmolo, Roberta; Atzeni, Giulia; Sanna, Erica; Nieddu, Salvatore; Onali, Alessia; Demuru, Laura; Paulis, Annalaura; Distinto, Simona; Corona, Angela; Esposito, Francesca; Meleddu, Rita; Cottiglia, Filippo; Bryant, Sharon D.; Maccioni, Elias; Tramontano, Enzo
Identifying potential allosteric inhibitors of ZIKV NS3pro through a combined computational and biochemical approach
2025-01-01 Demuru, L.; Lupia, A.; Nieddu, S.; Emmolo, R.; Paulis, A.; Esposito, F.; Distinto, S.; Bryant, S. D.; Onali, A.; Sanna, E.; Atzeni, G.; Cottiglia, F.; Grandi, N.; Corona, A.; Tramontano, E.; Maccioni, E.; Meleddu, R.
Synthesis and Evaluation of Thiazolidinone-Isatin Hybrids for Selective Inhibition of Cancer-Related Carbonic Anhydrases
2025-01-01 Onali, A.; Sanna, E.; Lupia, A.; Secci, D.; Atzeni, G.; Demuru, L.; Angeli, A.; Cottiglia, F.; Meleddu, R.; Emmolo, R.; Corona, A.; Maccioni, E.; Supuran, C. T.; Distinto, S.
Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B
2024-01-01 Meleddu, Rita; Fais, Antonella; Era, Benedetta; Floris, Sonia; Distinto, Simona; Lupia, Antonio; Cottiglia, Filippo; Onali, Alessia; Sanna, Erica; Secci, Daniela; Atzeni, Giulia; Demuru, Laura; Caboni, Pierluigi; Valenti, Donatella; Maccioni, Elias
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| A combination of MD-derived pharmacophores and structure-based strategy identifies dual allosteric inhibitors of NS2B-NS3 proteases in Zika and West Nile viruses | 1-gen-2026 | Lupia, Antonio; Nieddu, Salvatore; Demuru, Laura; Sanna, Erica; Onali, Alessia; Emmolo, Roberta; Malune, Paolo; Distinto, Simona; Atzeni, Giulia; Paulis, Annalaura; Meleddu, Rita; Cottiglia, Filippo; Esposito, Francesca; Corona, Angela; Bryant, Sharon D.; Maccioni, Elias; Tramontano, Enzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Structure-based virtual screening leads to the discovery of a 4,5-dihydropyrazole derivative as the first dual inhibitor of West Nile virus NS3 helicase and protease | 1-gen-2026 | Lupia, Antonio; Emmolo, Roberta; Atzeni, Giulia; Sanna, Erica; Nieddu, Salvatore; Onali, Alessia; Demuru, Laura; Paulis, Annalaura; Distinto, Simona; Corona, Angela; Esposito, Francesca; Meleddu, Rita; Cottiglia, Filippo; Bryant, Sharon D.; Maccioni, Elias; Tramontano, Enzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Identifying potential allosteric inhibitors of ZIKV NS3pro through a combined computational and biochemical approach | 1-gen-2025 | Demuru, L.; Lupia, A.; Nieddu, S.; Emmolo, R.; Paulis, A.; Esposito, F.; Distinto, S.; Bryant, S. D.; Onali, A.; Sanna, E.; Atzeni, G.; Cottiglia, F.; Grandi, N.; Corona, A.; Tramontano, E.; Maccioni, E.; Meleddu, R. | - | - |
| Synthesis and Evaluation of Thiazolidinone-Isatin Hybrids for Selective Inhibition of Cancer-Related Carbonic Anhydrases | 1-gen-2025 | Onali, A.; Sanna, E.; Lupia, A.; Secci, D.; Atzeni, G.; Demuru, L.; Angeli, A.; Cottiglia, F.; Meleddu, R.; Emmolo, R.; Corona, A.; Maccioni, E.; Supuran, C. T.; Distinto, S. | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B | 1-gen-2024 | Meleddu, Rita; Fais, Antonella; Era, Benedetta; Floris, Sonia; Distinto, Simona; Lupia, Antonio; Cottiglia, Filippo; Onali, Alessia; Sanna, Erica; Secci, Daniela; Atzeni, Giulia; Demuru, Laura; Caboni, Pierluigi; Valenti, Donatella; Maccioni, Elias | ACS MEDICINAL CHEMISTRY LETTERS | - |