FEIGUIN, FABIAN MARCELO
FEIGUIN, FABIAN MARCELO
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration
2023-01-01 Marzullo, Marta; Romano, Giulia; Pellacani, Claudia; Riccardi, Federico; Ciapponi, Laura; Feiguin, Fabian
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology
2022-01-01 Cappelli, Sara; Spalloni, Alida; Feiguin, FABIAN MARCELO; Visani, Giulia; Šušnjar, Urša; Leigh Brown, Anna; ALS Consortium, Nygc; de Bardi, Marco; Borsellino, Giovanna; Secrier, Maria; Phatnani, Hemali; Romano, Maurizio; Fratta, Pietro; Longone, Patrizia; Buratti., Emanuele
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology
2022-01-01 Cappelli, Sara; Spalloni, Alida; Visani, Giulia; Šušnjar, Urša; Brown, Anna-Leigh; Phatnani, Hemali; Kwan, Justin; Sareen, Dhruv; Broach, James R; Simmons, Zachary; Arcila-Londono, Ximena; Lee, Edward B; Van Deerlin, Vivianna M; Shneider, Neil A; Fraenkel, Ernest; Ostrow, Lyle W; Baas, Frank; Zaitlen, Noah; Berry, James D; Malaspina, Andrea; Fratta, Pietro; Cox, Gregory A; Thompson, Leslie M; Finkbeiner, Steve; Dardiotis, Efthimios; Miller, Timothy M; Chandran, Siddharthan; Pal, Suvankar; Hornstein, Eran; Macgowan, Daniel J; Heiman-Patterson, Terry; Hammell, Molly G; Patsopoulos, Nikolaos. A; Butovsky, Oleg; Dubnau, Joshua; Nath, Avindra; Bowser, Robert; Harms, Matt; Aronica, Eleonora; Poss, Mary; Phillips-Cremins, Jennifer; Crary, John; Atassi, Nazem; Lange, Dale J; Adams, Darius J; Stefanis, Leonidas; Gotkine, Marc; Baloh, Robert H; Babu, Suma; Raj, Towfique; Paganoni, Sabrina; Shalem, Ophir; Smith, Colin; Zhang, Bin; Harris, Brent; Broce, Iris; Drory, Vivian; Ravits, John; Mcmillan, Corey; Menon, Vilas; De Bardi, Marco; Borsellino, Giovanna; Secrier, Maria; Phatnani, Hemali; Romano, Maurizio; Fratta, Pietro; Longone, Patrizia; Buratti, Emanuele; Feiguin, Fabian
Immuno-electrophysiology on neuromuscular junctions of drosophila third instar larva
2021-01-01 Klima, R.; Romano, G.; Gbadamosi, M.; Megighian, A.; Feiguin, F.
Immunoprecipitation for Protein-Protein Interactions and for RNA Enrichment in Drosophila melanogaster
2021-01-01 Romano, G.; Klima, R.; Feiguin, F.
TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS
2021-01-01 Romano, G.; Holodkov, N.; Klima, R.; Feiguin, F.
Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance
2021-01-01 Cragnaz, L.; Spinelli, G.; De Conti, L.; Bureau, E. A.; Brownlees, J.; Feiguin, F.; Romano, V.; Skoko, N.; Klima, R.; Kettleborough, C. A.; Baralle, F. E.; Baralle, M.
TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity
2020-01-01 Romano, G.; Klima, R.; Feiguin, F.
TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles
2020-01-01 Strah, N.; Romano, G.; Introna, C.; Klima, R.; Marzullo, M.; Ciapponi, L.; Megighian, A.; Nizzardo, M.; Feiguin, F.
Downregulation of glutamic acid decarboxylase in Drosophila TDP- 43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses
2018-01-01 Romano, G.; Holodkov, N.; Klima, R.; Grilli, F.; Guarnaccia, C.; Nizzardo, M.; Rizzo, F.; Garcia, R.; Feiguin, F.
Loss of ISWI function in Drosophila nuclear bodies drives cytoplasmic redistribution of Drosophila TDP-43
2018-01-01 Lo Piccolo, L.; Bonaccorso, R.; Attardi, A.; Li Greci, L.; Romano, G.; Sollazzo, M.; Giurato, G.; Ingrassia, A. M. R.; Feiguin, F.; Corona, D. F. V.; Onorati, M. C.
RhoGAPp190: a potential player in tbph-mediated neurodegeneration in Drosophila
2018-01-01 Langellotti, S.; Romano, G.; Feiguin, F.; Baralle, F. E.; Romano, M.
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells
2017-01-01 Appocher, C.; Mohagheghi, F.; Cappelli, S.; Stuani, C.; Romano, M.; Feiguin, F.; Buratti, E.
WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models
2017-01-01 Di Giorgio, M. L.; Esposito, A.; Maccallini, P.; Micheli, E.; Bavasso, F.; Gallotta, I.; Verni, F.; Feiguin, F.; Cacchione, S.; Mccabe, B. D.; Di Schiavi, E.; Raffa, G. D.
A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects
2016-01-01 Langellotti, S.; Romano, V.; Romano, G.; Klima, R.; Feiguin, F.; Cragnaz, L.; Romano, M.; Baralle, F. E.
TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5′UTR
2016-01-01 Romano, M.; Feiguin, F.; Buratti, E.
An age-related reduction of brain TBPH/TDP-43 levels precedes the onset of locomotion defects in a Drosophila ALS model
2015-01-01 Cragnaz, L.; Klima, R.; De Conti, L.; Romano, G.; Feiguin, F.; Buratti, E.; Baralle, M.; Baralle, F. E.
Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms
2015-01-01 Romano, G.; Appocher, C.; Scorzeto, M.; Klima, R.; Baralle, F. E.; Megighian, A.; Feiguin, F.
Aggregate formation prevents dTDP-43 neurotoxicity in the Drosophila melanogaster eye
2014-01-01 Cragnaz, L.; Klima, R.; Skoko, N.; Budini, M.; Feiguin, F.; Baralle, F. E.
Chronological requirements of TDP-43 function in synaptic organization and locomotive control
2014-01-01 Romano, G.; Klima, R.; Buratti, E.; Verstreken, P.; Baralle, F. E.; Feiguin, F.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration | 1-gen-2023 | Marzullo, Marta; Romano, Giulia; Pellacani, Claudia; Riccardi, Federico; Ciapponi, Laura; Feiguin, Fabian | CELL DEATH DISCOVERY | - |
| NOS1AP is a novel molecular target and critical factor in TDP-43 pathology | 1-gen-2022 | Cappelli, Sara; Spalloni, Alida; Feiguin, FABIAN MARCELO; Visani, Giulia; Šušnjar, Urša; Leigh Brown, Anna; ALS Consortium, Nygc; de Bardi, Marco; Borsellino, Giovanna; Secrier, Maria; Phatnani, Hemali; Romano, Maurizio; Fratta, Pietro; Longone, Patrizia; Buratti., Emanuele | BRAIN COMMUNICATIONS | - |
| NOS1AP is a novel molecular target and critical factor in TDP-43 pathology | 1-gen-2022 | Cappelli, Sara; Spalloni, Alida; Visani, Giulia; Šušnjar, Urša; Brown, Anna-Leigh; Phatnani, Hemali; Kwan, Justin; Sareen, Dhruv; Broach, James R; Simmons, Zachary; Arcila-Londono, Ximena; Lee, Edward B; Van Deerlin, Vivianna M; Shneider, Neil A; Fraenkel, Ernest; Ostrow, Lyle W; Baas, Frank; Zaitlen, Noah; Berry, James D; Malaspina, Andrea; Fratta, Pietro; Cox, Gregory A; Thompson, Leslie M; Finkbeiner, Steve; Dardiotis, Efthimios; Miller, Timothy M; Chandran, Siddharthan; Pal, Suvankar; Hornstein, Eran; Macgowan, Daniel J; Heiman-Patterson, Terry; Hammell, Molly G; Patsopoulos, Nikolaos. A; Butovsky, Oleg; Dubnau, Joshua; Nath, Avindra; Bowser, Robert; Harms, Matt; Aronica, Eleonora; Poss, Mary; Phillips-Cremins, Jennifer; Crary, John; Atassi, Nazem; Lange, Dale J; Adams, Darius J; Stefanis, Leonidas; Gotkine, Marc; Baloh, Robert H; Babu, Suma; Raj, Towfique; Paganoni, Sabrina; Shalem, Ophir; Smith, Colin; Zhang, Bin; Harris, Brent; Broce, Iris; Drory, Vivian; Ravits, John; Mcmillan, Corey; Menon, Vilas; De Bardi, Marco; Borsellino, Giovanna; Secrier, Maria; Phatnani, Hemali; Romano, Maurizio; Fratta, Pietro; Longone, Patrizia; Buratti, Emanuele; Feiguin, Fabian | BRAIN COMMUNICATIONS | - |
| Immuno-electrophysiology on neuromuscular junctions of drosophila third instar larva | 1-gen-2021 | Klima, R.; Romano, G.; Gbadamosi, M.; Megighian, A.; Feiguin, F. | BIO-PROTOCOL | - |
| Immunoprecipitation for Protein-Protein Interactions and for RNA Enrichment in Drosophila melanogaster | 1-gen-2021 | Romano, G.; Klima, R.; Feiguin, F. | BIO-PROTOCOL | - |
| TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS | 1-gen-2021 | Romano, G.; Holodkov, N.; Klima, R.; Feiguin, F. | SCIENTIFIC REPORTS | - |
| Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance | 1-gen-2021 | Cragnaz, L.; Spinelli, G.; De Conti, L.; Bureau, E. A.; Brownlees, J.; Feiguin, F.; Romano, V.; Skoko, N.; Klima, R.; Kettleborough, C. A.; Baralle, F. E.; Baralle, M. | NEUROBIOLOGY OF DISEASE | - |
| TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity | 1-gen-2020 | Romano, G.; Klima, R.; Feiguin, F. | BMC BIOLOGY | - |
| TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles | 1-gen-2020 | Strah, N.; Romano, G.; Introna, C.; Klima, R.; Marzullo, M.; Ciapponi, L.; Megighian, A.; Nizzardo, M.; Feiguin, F. | BMC BIOLOGY | - |
| Downregulation of glutamic acid decarboxylase in Drosophila TDP- 43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses | 1-gen-2018 | Romano, G.; Holodkov, N.; Klima, R.; Grilli, F.; Guarnaccia, C.; Nizzardo, M.; Rizzo, F.; Garcia, R.; Feiguin, F. | SCIENTIFIC REPORTS | - |
| Loss of ISWI function in Drosophila nuclear bodies drives cytoplasmic redistribution of Drosophila TDP-43 | 1-gen-2018 | Lo Piccolo, L.; Bonaccorso, R.; Attardi, A.; Li Greci, L.; Romano, G.; Sollazzo, M.; Giurato, G.; Ingrassia, A. M. R.; Feiguin, F.; Corona, D. F. V.; Onorati, M. C. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| RhoGAPp190: a potential player in tbph-mediated neurodegeneration in Drosophila | 1-gen-2018 | Langellotti, S.; Romano, G.; Feiguin, F.; Baralle, F. E.; Romano, M. | PLOS ONE | - |
| Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells | 1-gen-2017 | Appocher, C.; Mohagheghi, F.; Cappelli, S.; Stuani, C.; Romano, M.; Feiguin, F.; Buratti, E. | NUCLEIC ACIDS RESEARCH | - |
| WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models | 1-gen-2017 | Di Giorgio, M. L.; Esposito, A.; Maccallini, P.; Micheli, E.; Bavasso, F.; Gallotta, I.; Verni, F.; Feiguin, F.; Cacchione, S.; Mccabe, B. D.; Di Schiavi, E.; Raffa, G. D. | NEUROBIOLOGY OF DISEASE | - |
| A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects | 1-gen-2016 | Langellotti, S.; Romano, V.; Romano, G.; Klima, R.; Feiguin, F.; Cragnaz, L.; Romano, M.; Baralle, F. E. | DISEASE MODELS & MECHANISMS | - |
| TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5′UTR | 1-gen-2016 | Romano, M.; Feiguin, F.; Buratti, E. | BRAIN RESEARCH | - |
| An age-related reduction of brain TBPH/TDP-43 levels precedes the onset of locomotion defects in a Drosophila ALS model | 1-gen-2015 | Cragnaz, L.; Klima, R.; De Conti, L.; Romano, G.; Feiguin, F.; Buratti, E.; Baralle, M.; Baralle, F. E. | NEUROSCIENCE | - |
| Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms | 1-gen-2015 | Romano, G.; Appocher, C.; Scorzeto, M.; Klima, R.; Baralle, F. E.; Megighian, A.; Feiguin, F. | HUMAN MOLECULAR GENETICS | - |
| Aggregate formation prevents dTDP-43 neurotoxicity in the Drosophila melanogaster eye | 1-gen-2014 | Cragnaz, L.; Klima, R.; Skoko, N.; Budini, M.; Feiguin, F.; Baralle, F. E. | NEUROBIOLOGY OF DISEASE | - |
| Chronological requirements of TDP-43 function in synaptic organization and locomotive control | 1-gen-2014 | Romano, G.; Klima, R.; Buratti, E.; Verstreken, P.; Baralle, F. E.; Feiguin, F. | NEUROBIOLOGY OF DISEASE | - |