The aim of this study was to analyse the correlation between blood lead (PbB) and hair lead (PbH) in Sardinian children. Th e sample consisted of 330 children (126 boys and 204 girls) from three Sardinian towns with diff erent environmental backgrounds: Portoscuso, Sant’Antioco, and Sestu. Th e boys of Portoscuso have the highest median value of PbB (10.86 μg/dL), followed by the girls of Portoscuso (7.24 μg/dL); they are followed, but with much lower values, by the boys of Sant'Antioco (4.22 μg/dL) and Sestu (4.06 μg/dL), and lastly by the girls of Sant'Antioco (3.50 μg/dL) and Sestu (3.39 μg/dL). Th ere is a similar pattern for the PbH values: the Portoscuso boys have the highest median value (10.00 μg/g), followed by the Portoscuso girls (7.21 μg/g), Sant'Antioco boys (5.44 μg/g), Sant’Antioco girls (4.69 μg/g) and fi nally the Sestu boys (3.79 μg/g) and girls (1.56 μg/g). Th e values of the Bravais-Pearson coeffi cient of correlation between logPbB and logPbH are statistically signifi cant both for the total sample (r=0.4351; p≤0.001) and for the sexes considered separately (r=0.3989, p≤0.001, for males; r=0.3801, p≤0.001, for females). It should be noted that a high percentage of unexplained variance persists in the total sample (81.07%) and in males (84.09%) and females (85.55%) separately. Th e pattern among samples with diff erent environmental backgrounds and the signifi cant correlations between the logPbB and logPbH values suggest that hair can be used as a suitable biomarker of lead exposure.

Correlation between blood and hair lead levels in boys and girls of Sardinia (Italy)

SANNA, EMANUELE;VALLASCAS, ELISABETTA;
2007-01-01

Abstract

The aim of this study was to analyse the correlation between blood lead (PbB) and hair lead (PbH) in Sardinian children. Th e sample consisted of 330 children (126 boys and 204 girls) from three Sardinian towns with diff erent environmental backgrounds: Portoscuso, Sant’Antioco, and Sestu. Th e boys of Portoscuso have the highest median value of PbB (10.86 μg/dL), followed by the girls of Portoscuso (7.24 μg/dL); they are followed, but with much lower values, by the boys of Sant'Antioco (4.22 μg/dL) and Sestu (4.06 μg/dL), and lastly by the girls of Sant'Antioco (3.50 μg/dL) and Sestu (3.39 μg/dL). Th ere is a similar pattern for the PbH values: the Portoscuso boys have the highest median value (10.00 μg/g), followed by the Portoscuso girls (7.21 μg/g), Sant'Antioco boys (5.44 μg/g), Sant’Antioco girls (4.69 μg/g) and fi nally the Sestu boys (3.79 μg/g) and girls (1.56 μg/g). Th e values of the Bravais-Pearson coeffi cient of correlation between logPbB and logPbH are statistically signifi cant both for the total sample (r=0.4351; p≤0.001) and for the sexes considered separately (r=0.3989, p≤0.001, for males; r=0.3801, p≤0.001, for females). It should be noted that a high percentage of unexplained variance persists in the total sample (81.07%) and in males (84.09%) and females (85.55%) separately. Th e pattern among samples with diff erent environmental backgrounds and the signifi cant correlations between the logPbB and logPbH values suggest that hair can be used as a suitable biomarker of lead exposure.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/106985
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