In the present study, the bezafibrate levels were measured in serum of rats treated with lead nitrate using a high performance liquid chromatography (HPLC) method. The results have shown that the peak corresponding to bezafibrate in the chromatogram is reduced in serum of rats treated with bezafibrate plus lead, indicating that lead treatment accelerates the metabolism of bezafibrate in rats. (C) 1998 Elsevier Science S.A. All rights reserved.
Determination of bezafibrate concentration by high performance liquid-chromatography in serum of rats treated with lead nitrate
FADDA, ANNA MARIA;
1998-01-01
Abstract
In the present study, the bezafibrate levels were measured in serum of rats treated with lead nitrate using a high performance liquid chromatography (HPLC) method. The results have shown that the peak corresponding to bezafibrate in the chromatogram is reduced in serum of rats treated with bezafibrate plus lead, indicating that lead treatment accelerates the metabolism of bezafibrate in rats. (C) 1998 Elsevier Science S.A. All rights reserved.
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