Ultradian rhythmicity has been showed in many behavioural parameters in animals as well as in humans. We investigated the existence of a Basic Rest-Activity Cycle (BRAC) rhythm in amplitude fluctuations of mice's Visual Evoked Potential (VEP) primary component, usually matched to the human N1-P2. Two imbred strains of mice, C57BL/6 and DBA/2J, were used to verify the influence of genetics on biological rhythm as well. Relevant literature reportes a different level of plasticity for the two strains we considered. C57 strain is considered less plastic respect to DBA strain. Results revealed the existence of an evident rhythm in the parameter under study. This rhythm shows similar period within each strain, but significatively different periods between strains. Observed periods are near to specie-specific reported BRAC cycle. Genetic Hypothesis is suggested to explain differences between strains in expression of ultradian rhythm.
ULTRADIAN RHYTHMS IN THE N1-P2 AMPLITUDE OF THE VISUAL EVOKED POTENTIAL IN TWO IMBRED STRAINS OF MICE: DBA/2J AND C57BL/6
CONTE, STELLA;
1995-01-01
Abstract
Ultradian rhythmicity has been showed in many behavioural parameters in animals as well as in humans. We investigated the existence of a Basic Rest-Activity Cycle (BRAC) rhythm in amplitude fluctuations of mice's Visual Evoked Potential (VEP) primary component, usually matched to the human N1-P2. Two imbred strains of mice, C57BL/6 and DBA/2J, were used to verify the influence of genetics on biological rhythm as well. Relevant literature reportes a different level of plasticity for the two strains we considered. C57 strain is considered less plastic respect to DBA strain. Results revealed the existence of an evident rhythm in the parameter under study. This rhythm shows similar period within each strain, but significatively different periods between strains. Observed periods are near to specie-specific reported BRAC cycle. Genetic Hypothesis is suggested to explain differences between strains in expression of ultradian rhythm.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.