CORONA, ANGELA
CORONA, ANGELA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase
2015-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias
1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity
2020-01-01 Desantis, Jenny; Massari, Serena; Corona, Angela; Astolfi, Andrea; Sabatini, Stefano; Manfroni, Giuseppe; Palazzotti, Deborah; Cecchetti, Violetta; Pannecouque, Christophe; Tramontano, Enzo; Tabarrini, Oriana
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication
2020-01-01 Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication
2014-01-01 Corona, Angela; Meleddu, R.; Esposito, E.; Distinto, S.; Bianco, G.; Maccioni, E.; Tramontano, E. .
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function
2011-01-01 Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias
5-arylaminouracil derivatives as potential dual-action agents
2015-01-01 Matyugina, Es; Novikov, Ms; Babkov, Da; Valuev Elliston, Vt; Vanpouille, C; Zicari, S; Corona, Angela; Tramontano, Enzo; Margolis, Lb; Khandazhinskaya, Al; Kochetkov, Sn
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives
2014-01-01 Corona, Angela; Cosconati, S; Tierry, S; Pescatore, L; Di Leva F., S; Subra, F.; Delelis, O; Esposito, Francesca; Costi, R; Novellino, E; Di Santo, R; Tramontano, E.
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β
2015-01-01 Cannas, V; Daino, Gl; Corona, Angela; Esposito, Francesca; Tramontano, Enzo
A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity
2016-01-01 Palomba, M.; Rossi, L.; Sancineto, L.; Tramontano, E.; Corona, A.; Bagnoli, L.; Santi, C.; Pannecouque, C.; Tabarrini, O.; Marini, F
Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase
2013-01-01 Corona, Angela; Masaoka, T; Tocco, Graziella; Tramontano, Enzo; Le Grice, Sfj
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases
2011-01-01 Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo
An efficient route to novel uracil-based drug-like molecules
2015-01-01 Babkov, Da; Chizhov, Ao; Khandazhinskaya, Al; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; SELEY RADTKE, Kl; Novikov, Ms
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors
2014-01-01 Carcelli, M; Rogolino, D; Sechi, M; Rispoli, G; Fisicaro, E; Compari, C; Grandi, Nicole; Corona, Angela; Tramontano, Enzo; Pannecouque, C; Naesens, L.
Antityrosinase activity of Euphorbia characias extracts
2015-01-01 Pintus, Francesca; Spano', Delia; Corona, Angela; Medda, Rosaria
Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules
2018-01-01 Fanunza, Elisa; Frau, Aldo; Corona, Angela; Tramontano, Enzo
Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase
2014-01-01 Costi, R; Métifiot, M; Chung, S; CUZZUCOLI CRUCITTI, G; Maddali, K; Pescatori, L; Messore, A; Madia, Vn; Pupo, G; Scipione, L; Tortorella, S; DI LEVA, Fs; Cosconati, S; Marinelli, L; Novellino, E; LE GRICE, Sf; Corona, Angela; Pommier, Y; Marchand, C; DI SANTO, R.
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors
2016-01-01 Schneider, Anna; Corona, Angela; Spöring, Imke; Jordan, Mareike; Buchholz, Bernd; Maccioni, Elias; Di Santo, Roberto; Bodem, Jochen; Tramontano, Enzo; Wöhrl, Birgitta M.
Biological activities of aerial parts extracts of Euphorbia characias
2016-01-01 Pisano, MARIA BARBARA; Cosentino, Sofia; Viale, Silvia; Spano', Delia; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Montoro, P; Tuberoso, CARLO IGNAZIO GIOVANNI; Medda, Rosaria; Pintus, Francesca
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023-01-01 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development?
2014-01-01 Corona, Angela; Esposito, Francesca; Tramontano, Enzo
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| (3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase | 1-gen-2015 | Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| 1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity | 1-gen-2020 | Desantis, Jenny; Massari, Serena; Corona, Angela; Astolfi, Andrea; Sabatini, Stefano; Manfroni, Giuseppe; Palazzotti, Deborah; Cecchetti, Violetta; Pannecouque, Christophe; Tramontano, Enzo; Tabarrini, Oriana | MOLECULES | - |
| 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication | 1-gen-2020 | Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo | MOLECULES | - |
| 2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication | 1-gen-2014 | Corona, Angela; Meleddu, R.; Esposito, E.; Distinto, S.; Bianco, G.; Maccioni, E.; Tramontano, E. . | - | - |
| 3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function | 1-gen-2011 | Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| 5-arylaminouracil derivatives as potential dual-action agents | 1-gen-2015 | Matyugina, Es; Novikov, Ms; Babkov, Da; Valuev Elliston, Vt; Vanpouille, C; Zicari, S; Corona, Angela; Tramontano, Enzo; Margolis, Lb; Khandazhinskaya, Al; Kochetkov, Sn | ACTA NATURAE | - |
| A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives | 1-gen-2014 | Corona, Angela; Cosconati, S; Tierry, S; Pescatore, L; Di Leva F., S; Subra, F.; Delelis, O; Esposito, Francesca; Costi, R; Novellino, E; Di Santo, R; Tramontano, E. | - | - |
| A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β | 1-gen-2015 | Cannas, V; Daino, Gl; Corona, Angela; Esposito, Francesca; Tramontano, Enzo | THE JOURNAL OF INFECTIOUS DISEASES | - |
| A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity | 1-gen-2016 | Palomba, M.; Rossi, L.; Sancineto, L.; Tramontano, E.; Corona, A.; Bagnoli, L.; Santi, C.; Pannecouque, C.; Tabarrini, O.; Marini, F | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
| Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase | 1-gen-2013 | Corona, Angela; Masaoka, T; Tocco, Graziella; Tramontano, Enzo; Le Grice, Sfj | FUTURE MEDICINAL CHEMISTRY | - |
| Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases | 1-gen-2011 | Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo | THE FEBS JOURNAL | - |
| An efficient route to novel uracil-based drug-like molecules | 1-gen-2015 | Babkov, Da; Chizhov, Ao; Khandazhinskaya, Al; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; SELEY RADTKE, Kl; Novikov, Ms | SYNTHESIS | - |
| Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors | 1-gen-2014 | Carcelli, M; Rogolino, D; Sechi, M; Rispoli, G; Fisicaro, E; Compari, C; Grandi, Nicole; Corona, Angela; Tramontano, Enzo; Pannecouque, C; Naesens, L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Antityrosinase activity of Euphorbia characias extracts | 1-gen-2015 | Pintus, Francesca; Spano', Delia; Corona, Angela; Medda, Rosaria | PEERJ | - |
| Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules | 1-gen-2018 | Fanunza, Elisa; Frau, Aldo; Corona, Angela; Tramontano, Enzo | ANNUAL REPORTS IN MEDICINAL CHEMISTRY | - |
| Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase | 1-gen-2014 | Costi, R; Métifiot, M; Chung, S; CUZZUCOLI CRUCITTI, G; Maddali, K; Pescatori, L; Messore, A; Madia, Vn; Pupo, G; Scipione, L; Tortorella, S; DI LEVA, Fs; Cosconati, S; Marinelli, L; Novellino, E; LE GRICE, Sf; Corona, Angela; Pommier, Y; Marchand, C; DI SANTO, R. | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors | 1-gen-2016 | Schneider, Anna; Corona, Angela; Spöring, Imke; Jordan, Mareike; Buchholz, Bernd; Maccioni, Elias; Di Santo, Roberto; Bodem, Jochen; Tramontano, Enzo; Wöhrl, Birgitta M. | NUCLEIC ACIDS RESEARCH | - |
| Biological activities of aerial parts extracts of Euphorbia characias | 1-gen-2016 | Pisano, MARIA BARBARA; Cosentino, Sofia; Viale, Silvia; Spano', Delia; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Montoro, P; Tuberoso, CARLO IGNAZIO GIOVANNI; Medda, Rosaria; Pintus, Francesca | BIOMED RESEARCH INTERNATIONAL | - |
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1-gen-2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? | 1-gen-2014 | Corona, Angela; Esposito, Francesca; Tramontano, Enzo | FUTURE VIROLOGY | - |