CORONA, ANGELA
CORONA, ANGELA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Design, synthesis and biological evaluation of Thiazolo[3, 2-a]Pyrimidine derivatives as novel RNase H inhibitors
2024-01-01 Zhao, K. -X.; Zhang, Y. -Y.; Wang, J. -S.; Wang, S.; Corona, A.; Maloccu, S.; Tramontano, E.; Pannecouque, C.; De Clercq, E.; Meng, G.; Wang, L.; Chen, F. -E.
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
2024-01-01 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea
Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity
2024-01-01 Paulis, A.; Onali, A.; Vidalain, P. O.; Lotteau, V.; Jaquemin, C.; Corona, A.; Distinto, S.; Delogu, G. L.; Tramontano, E.
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors
2024-01-01 Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And
Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy
2024-01-01 Zhu, X. -D.; Corona, A.; Maloccu, S.; Tramontano, E.; Wang, S.; Pannecouque, C.; De Clercq, E.; Meng, G.; Chen, F. -E.
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
2023-01-01 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E.
Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication
2023-01-01 Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B.
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023-01-01 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action
2023-01-01 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication
2023-01-01 Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo
Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action
2023-01-01 Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M
Editorial: Viruses, innate immunity, and antiviral strategies: from basic research to clinical applications
2023-01-01 Fanunza, Elisa; Corona, Angela
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France)
2023-01-01 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca
Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus
2023-01-01 Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function
2023-01-01 Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
2023-01-01 Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And
Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds
2023-01-01 Al Nasr, Ibrahim S; Corona, Angela; Koko, Waleed S; Khan, Tariq A; Ben Said, Ridha; Daoud, Ismail; Rahali, Seyfeddine; Tramontano, Enzo; Schobert, Rainer; Amdouni, Noureddine; Biersack, Bernhard
Visible Light-Mediated Inactivation of H1N1 Virus UsingPolymer-Based Heterojunction Photocatalyst
2023-01-01 Porcu, Stefania; Maloccu, Stefania; Corona, Angela; Hazra, Moulika; David, TULLIA CARLA; Chiriu, Daniele; Carbonaro, CARLO MARIA; Tramontano, Enzo; Ricci, PIER CARLO
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production
2022-01-01 Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort
2022-01-01 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Design, synthesis and biological evaluation of Thiazolo[3, 2-a]Pyrimidine derivatives as novel RNase H inhibitors | 1-gen-2024 | Zhao, K. -X.; Zhang, Y. -Y.; Wang, J. -S.; Wang, S.; Corona, A.; Maloccu, S.; Tramontano, E.; Pannecouque, C.; De Clercq, E.; Meng, G.; Wang, L.; Chen, F. -E. | BIOORGANIC CHEMISTRY | - |
| Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex | 1-gen-2024 | Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea | VIRUS RESEARCH | - |
| Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity | 1-gen-2024 | Paulis, A.; Onali, A.; Vidalain, P. O.; Lotteau, V.; Jaquemin, C.; Corona, A.; Distinto, S.; Delogu, G. L.; Tramontano, E. | VIRUS RESEARCH | - |
| New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors | 1-gen-2024 | Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And | PHARMACEUTICALS | - |
| Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy | 1-gen-2024 | Zhu, X. -D.; Corona, A.; Maloccu, S.; Tramontano, E.; Wang, S.; Pannecouque, C.; De Clercq, E.; Meng, G.; Chen, F. -E. | MOLECULES | - |
| 5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action | 1-gen-2023 | Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication | 1-gen-2023 | Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B. | VIRUSES | - |
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1-gen-2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action | 1-gen-2023 | Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello | VIRUSES | - |
| Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication | 1-gen-2023 | Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action | 1-gen-2023 | Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M | ANTIVIRAL RESEARCH | - |
| Editorial: Viruses, innate immunity, and antiviral strategies: from basic research to clinical applications | 1-gen-2023 | Fanunza, Elisa; Corona, Angela | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) | 1-gen-2023 | Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca | PHARMACEUTICALS | - |
| Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus | 1-gen-2023 | Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
| Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function | 1-gen-2023 | Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca | VIRUS RESEARCH | - |
| Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach | 1-gen-2023 | Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - |
| Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds | 1-gen-2023 | Al Nasr, Ibrahim S; Corona, Angela; Koko, Waleed S; Khan, Tariq A; Ben Said, Ridha; Daoud, Ismail; Rahali, Seyfeddine; Tramontano, Enzo; Schobert, Rainer; Amdouni, Noureddine; Biersack, Bernhard | BIOORGANIC & MEDICINAL CHEMISTRY | - |
| Visible Light-Mediated Inactivation of H1N1 Virus UsingPolymer-Based Heterojunction Photocatalyst | 1-gen-2023 | Porcu, Stefania; Maloccu, Stefania; Corona, Angela; Hazra, Moulika; David, TULLIA CARLA; Chiriu, Daniele; Carbonaro, CARLO MARIA; Tramontano, Enzo; Ricci, PIER CARLO | POLYMERS | - |
| Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production | 1-gen-2022 | Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort | 1-gen-2022 | Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter | SCIENTIFIC DATA | - |