| Nome |
# |
|
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions, file e2f56ed7-ec87-3eaf-e053-3a05fe0a5d97
|
607
|
|
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties, file e2f56ed3-d7ec-3eaf-e053-3a05fe0a5d97
|
520
|
|
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones, file e2f56ed5-0382-3eaf-e053-3a05fe0a5d97
|
503
|
|
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles, file e2f56ed8-91d6-3eaf-e053-3a05fe0a5d97
|
493
|
|
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity, file e2f56ed7-e151-3eaf-e053-3a05fe0a5d97
|
472
|
|
Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor, file e2f56ed4-31f5-3eaf-e053-3a05fe0a5d97
|
461
|
|
Critical role for prokineticin 2 in CNS autoimmunity, file e2f56ed3-8981-3eaf-e053-3a05fe0a5d97
|
449
|
|
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors, file e2f56ed8-4f7b-3eaf-e053-3a05fe0a5d97
|
418
|
|
Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment, file e2f56ed9-4fc7-3eaf-e053-3a05fe0a5d97
|
371
|
|
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen, file e2f56ed8-fdac-3eaf-e053-3a05fe0a5d97
|
262
|
|
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors, file e2f56ed8-99b7-3eaf-e053-3a05fe0a5d97
|
217
|
|
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy, file e2f56ed7-10b6-3eaf-e053-3a05fe0a5d97
|
210
|
|
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones, file e2f56ed8-4299-3eaf-e053-3a05fe0a5d97
|
210
|
|
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation, file e2f56ed8-6c8d-3eaf-e053-3a05fe0a5d97
|
210
|
|
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents, file e2f56ed8-e56d-3eaf-e053-3a05fe0a5d97
|
202
|
|
Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode, file e2f56ed4-7baa-3eaf-e053-3a05fe0a5d97
|
195
|
|
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context, file e2f56ed3-e642-3eaf-e053-3a05fe0a5d97
|
180
|
|
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen, file e2f56ed9-1018-3eaf-e053-3a05fe0a5d97
|
180
|
|
Synthesis, characterization, HSA/DNA interactions and antitumor activity of new [Ru(η6-p-cymene)Cl2(L)] complexes, file e2f56ed9-a89e-3eaf-e053-3a05fe0a5d97
|
151
|
|
Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes, file e2f56ed4-bd85-3eaf-e053-3a05fe0a5d97
|
145
|
|
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives, file e2f56ed8-f11e-3eaf-e053-3a05fe0a5d97
|
138
|
|
Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel, file e2f56ed3-dab5-3eaf-e053-3a05fe0a5d97
|
118
|
|
Cholinium-Based Ionic Liquids from Hydroxycinnamic Acids as New Promising Bioactive Agents: A Combined Experimental and Theoretical Investigation, file e2f56eda-013b-3eaf-e053-3a05fe0a5d97
|
101
|
|
Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide, file e2f56ed3-e30f-3eaf-e053-3a05fe0a5d97
|
95
|
|
Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore, file e2f56ed8-2f1a-3eaf-e053-3a05fe0a5d97
|
92
|
|
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors, file e2f56ed9-4a5d-3eaf-e053-3a05fe0a5d97
|
85
|
|
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication, file e2f56ed8-ef23-3eaf-e053-3a05fe0a5d97
|
80
|
|
Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy, file e2f56ed8-5ba6-3eaf-e053-3a05fe0a5d97
|
66
|
|
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization, file e2f56ed3-c92c-3eaf-e053-3a05fe0a5d97
|
65
|
|
Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain, file e2f56ed3-e21f-3eaf-e053-3a05fe0a5d97
|
54
|
|
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents, file e2f56eda-1db5-3eaf-e053-3a05fe0a5d97
|
44
|
|
Novel Anti-proliferative Agents, file 7c82b1fd-50e9-43d3-9f9e-46dfbd332839
|
32
|
|
Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets, file e2f56eda-55dc-3eaf-e053-3a05fe0a5d97
|
23
|
|
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition, file 7de6dee0-7242-4066-bccb-2b49019175da
|
20
|
|
Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives, file daaf794b-1d29-4f08-b99a-a1829dce56e3
|
20
|
|
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions, file e2f56ed6-c3c4-3eaf-e053-3a05fe0a5d97
|
18
|
|
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo, file e2f56ed6-d800-3eaf-e053-3a05fe0a5d97
|
16
|
|
PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development, file e2f56ed3-fa25-3eaf-e053-3a05fe0a5d97
|
15
|
|
TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives, file e2f56ed3-f9fa-3eaf-e053-3a05fe0a5d97
|
14
|
|
null, file e2f56ed8-7b75-3eaf-e053-3a05fe0a5d97
|
14
|
|
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation, file e2f56eda-b6b4-3eaf-e053-3a05fe0a5d97
|
14
|
|
Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity, file 68231487-480f-44c1-be80-3b68e7e5d26a
|
13
|
|
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors, file e2f56eda-1b46-3eaf-e053-3a05fe0a5d97
|
11
|
|
Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors, file 280f0652-38a2-4c34-a7db-94405a57a4f8
|
10
|
|
Novel propanamides as fatty acid amide hydrolase inhibitors, file e2f56ed6-88c5-3eaf-e053-3a05fe0a5d97
|
10
|
|
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity, file e2f56ed4-0534-3eaf-e053-3a05fe0a5d97
|
9
|
|
Special Issue “Novel Anti-Proliferative Agents”, file a48f8291-9857-477f-bbf1-4ba5c311334d
|
7
|
|
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions, file e2f56ed6-be95-3eaf-e053-3a05fe0a5d97
|
7
|
|
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo, file e2f56ed6-feeb-3eaf-e053-3a05fe0a5d97
|
7
|
|
Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain, file e2f56ed3-aec4-3eaf-e053-3a05fe0a5d97
|
6
|
|
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones, file e2f56ed8-57f7-3eaf-e053-3a05fe0a5d97
|
6
|
|
Interaction and reactivity of synthetic aminoisoflavones with metal-free and metalassociated amyloid-beta, file e2f56ed3-fcbe-3eaf-e053-3a05fe0a5d97
|
5
|
|
Novel propanamides as fatty acid amide hydrolase inhibitors, file e2f56ed6-8a4d-3eaf-e053-3a05fe0a5d97
|
5
|
|
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors, file e2f56ed8-d1ff-3eaf-e053-3a05fe0a5d97
|
5
|
|
Synthesis and evaluation of antitumoral activity of ester and amide derivatives of 2-arylamino-6- trifluoromethyl-3-pyridinecarboxylic acids, file e2f56ed3-a53d-3eaf-e053-3a05fe0a5d97
|
4
|
|
null, file e2f56ed3-bb34-3eaf-e053-3a05fe0a5d97
|
4
|
|
Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore, file e2f56ed3-bcc2-3eaf-e053-3a05fe0a5d97
|
4
|
|
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity, file e2f56ed3-e387-3eaf-e053-3a05fe0a5d97
|
4
|
|
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis, file e2f56ed4-9375-3eaf-e053-3a05fe0a5d97
|
4
|
|
Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations, file e2f56ed4-c80f-3eaf-e053-3a05fe0a5d97
|
4
|
|
Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita, file e2f56ed5-234a-3eaf-e053-3a05fe0a5d97
|
4
|
|
null, file e2f56ed7-326c-3eaf-e053-3a05fe0a5d97
|
4
|
|
null, file e2f56ed8-c1f5-3eaf-e053-3a05fe0a5d97
|
4
|
|
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents, file e2f56ed9-cac1-3eaf-e053-3a05fe0a5d97
|
4
|
|
2-Acylhydrazino-5-arylpyrrole derivatives: Synthesis and antifungal activity evaluation, file e2f56ed3-a63d-3eaf-e053-3a05fe0a5d97
|
3
|
|
Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues, file e2f56ed3-bb75-3eaf-e053-3a05fe0a5d97
|
3
|
|
Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel, file e2f56ed3-e003-3eaf-e053-3a05fe0a5d97
|
3
|
|
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity, file e2f56ed3-e388-3eaf-e053-3a05fe0a5d97
|
3
|
|
An important role for prokineticin 2 in autoimmune CNS demyelination, file e2f56ed4-49ca-3eaf-e053-3a05fe0a5d97
|
3
|
|
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis, file e2f56ed4-8f9a-3eaf-e053-3a05fe0a5d97
|
3
|
|
Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain, file e2f56ed6-4523-3eaf-e053-3a05fe0a5d97
|
3
|
|
Palladium(II) and platinum(II), (IV) complexes of 2-aminopyrimidine derivatives, file e2f56ed6-92c0-3eaf-e053-3a05fe0a5d97
|
3
|
|
null, file e2f56ed6-9b98-3eaf-e053-3a05fe0a5d97
|
3
|
|
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors, file e2f56ed9-2aa2-3eaf-e053-3a05fe0a5d97
|
3
|
|
Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors, file 3479af59-02ff-4405-a91b-06ffc81df009
|
2
|
|
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors, file 82615408-bb6e-402c-ac17-7cae78635680
|
2
|
|
Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model, file 8547de6e-ab83-4092-b4cb-ef0ffa256fbf
|
2
|
|
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors, file c25cfbe5-0c40-404c-8b76-a2c9bf2444ca
|
2
|
|
Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors, file d0fae39a-ae2f-40c7-9555-10c55d4d8cd9
|
2
|
|
Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin, file d70f56c8-0419-4050-a5bb-02f9e5310ab9
|
2
|
|
Synthesis and in vitro antitumor activity of new 4,5-dihydropyrazole derivatives, file e2f56ed3-a236-3eaf-e053-3a05fe0a5d97
|
2
|
|
A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists, file e2f56ed3-a794-3eaf-e053-3a05fe0a5d97
|
2
|
|
Synthesis and biological evaluation of novel acylhydrazone derivatives as potential antitumor agents, file e2f56ed3-b438-3eaf-e053-3a05fe0a5d97
|
2
|
|
Synthesis of new N-(2-(trifluoromethyl)pyridin-4-yl)anthranilic acid derivatives and their evaluation as anticancer agents, file e2f56ed3-bcba-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed3-bcf8-3eaf-e053-3a05fe0a5d97
|
2
|
|
Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide, file e2f56ed3-bd0a-3eaf-e053-3a05fe0a5d97
|
2
|
|
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties, file e2f56ed3-bdb7-3eaf-e053-3a05fe0a5d97
|
2
|
|
Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen, file e2f56ed3-d7a8-3eaf-e053-3a05fe0a5d97
|
2
|
|
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins, file e2f56ed3-e72a-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed4-49f1-3eaf-e053-3a05fe0a5d97
|
2
|
|
Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives, file e2f56ed4-ee3f-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-92f4-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-939a-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-95de-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-96e9-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-97ec-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-97f2-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-9854-3eaf-e053-3a05fe0a5d97
|
2
|
|
Reaction of enaminonitriles with isocyanates. Synthesis of new 2-oxo- and 6-oxopyrimidines, file e2f56ed6-9a0d-3eaf-e053-3a05fe0a5d97
|
2
|
|
null, file e2f56ed6-9af1-3eaf-e053-3a05fe0a5d97
|
2
|
| Totale |
7.803 |