TRAMONTANO, ENZO
TRAMONTANO, ENZO
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Cognitive Impairment and Risk of Depressive Episodes from a Bipolar Spectrum Perspective: A Case-Control Study in Older Adults during the COVID-19 Lockdown
2024-01-01 Primavera, Diego; Bert, Fabrizio; Romano, Ferdinando; Giuseppe La Torre, ; AVILES GONZALEZ, CESAR IVAN; Perra, Alessandra; Pedro Fragoso Castilla, ; Martha Esther Guerra Muñoz, ; Tramontano, Enzo; Machado, Sergio; Nardi, Ae; Sancassiani, Federica; Carta, Mg
Design, synthesis and biological evaluation of Thiazolo[3, 2-a]Pyrimidine derivatives as novel RNase H inhibitors
2024-01-01 Zhao, K. -X.; Zhang, Y. -Y.; Wang, J. -S.; Wang, S.; Corona, A.; Maloccu, S.; Tramontano, E.; Pannecouque, C.; De Clercq, E.; Meng, G.; Wang, L.; Chen, F. -E.
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
2024-01-01 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea
Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity
2024-01-01 Paulis, A.; Onali, A.; Vidalain, P. O.; Lotteau, V.; Jaquemin, C.; Corona, A.; Distinto, S.; Delogu, G. L.; Tramontano, E.
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors
2024-01-01 Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And
Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy
2024-01-01 Zhu, X. -D.; Corona, A.; Maloccu, S.; Tramontano, E.; Wang, S.; Pannecouque, C.; De Clercq, E.; Meng, G.; Chen, F. -E.
The impact of insularity on SARS-CoV-2 diffusion: Recapitulating three years of COVID-19 pandemic in the island of Sardinia
2024-01-01 Grandi, N.; Cusano, R.; Piras, G.; Fiamma, M.; Monne, M. I.; Fancello, T.; Milia, J.; Orru, S.; Scognamiglio, S.; Serra, C.; Mameli, G.; Uzzau, S.; Orru, G.; Palmas, A. D.; Rubino, S.; Tramontano, E.
The Stability of Social and Behavioral Rhythms and Unexpected Low Rate of Relevant Depressive Symptoms in Old Adults during the COVID-19 Pandemic
2024-01-01 Sancassiani, Federica; Cossu, Giulia; Cantone, Elisa; Romano, Ferdinando; Perra, Alessandra; Urban, Antonio; Pinna, Samantha; Del Giacco, Stefano; Littera, Roberto; Firinu, Davide; Chessa, Luchino; Tramontano, Enzo; Nardi, Antonio Egidio; Carta, Mauro Giovanni
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
2023-01-01 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E.
Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication
2023-01-01 Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B.
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023-01-01 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
Comparing the responses of countries and National Health Systems to the COVID-19 pandemic: a critical analysis with a case-report series
2023-01-01 Carta, M. G.; Orru, G.; Littera, R.; Firinu, D.; Chessa, L.; Cossu, G.; Primavera, D.; DEL GIACCO, S.; Tramontano, E.; Manocchio, N.; Buonomo, C.; Scano, A.
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action
2023-01-01 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello
Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
2023-01-01 Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F.
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication
2023-01-01 Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo
Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action
2023-01-01 Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France)
2023-01-01 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca
Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages
2023-01-01 Grandi, Nicole; Erbì, Maria Chiara; Scognamiglio, Sante; Tramontano, Enzo
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
2023-01-01 Scognamiglio, Sante; Grandi, Nicole; Pessiu, Eleonora; Tramontano, Enzo
Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus
2023-01-01 Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Cognitive Impairment and Risk of Depressive Episodes from a Bipolar Spectrum Perspective: A Case-Control Study in Older Adults during the COVID-19 Lockdown | 1-gen-2024 | Primavera, Diego; Bert, Fabrizio; Romano, Ferdinando; Giuseppe La Torre, ; AVILES GONZALEZ, CESAR IVAN; Perra, Alessandra; Pedro Fragoso Castilla, ; Martha Esther Guerra Muñoz, ; Tramontano, Enzo; Machado, Sergio; Nardi, Ae; Sancassiani, Federica; Carta, Mg | PSYCHIATRY INTERNATIONAL | - |
| Design, synthesis and biological evaluation of Thiazolo[3, 2-a]Pyrimidine derivatives as novel RNase H inhibitors | 1-gen-2024 | Zhao, K. -X.; Zhang, Y. -Y.; Wang, J. -S.; Wang, S.; Corona, A.; Maloccu, S.; Tramontano, E.; Pannecouque, C.; De Clercq, E.; Meng, G.; Wang, L.; Chen, F. -E. | BIOORGANIC CHEMISTRY | - |
| Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex | 1-gen-2024 | Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea | VIRUS RESEARCH | - |
| Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity | 1-gen-2024 | Paulis, A.; Onali, A.; Vidalain, P. O.; Lotteau, V.; Jaquemin, C.; Corona, A.; Distinto, S.; Delogu, G. L.; Tramontano, E. | VIRUS RESEARCH | - |
| New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors | 1-gen-2024 | Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And | PHARMACEUTICALS | - |
| Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy | 1-gen-2024 | Zhu, X. -D.; Corona, A.; Maloccu, S.; Tramontano, E.; Wang, S.; Pannecouque, C.; De Clercq, E.; Meng, G.; Chen, F. -E. | MOLECULES | - |
| The impact of insularity on SARS-CoV-2 diffusion: Recapitulating three years of COVID-19 pandemic in the island of Sardinia | 1-gen-2024 | Grandi, N.; Cusano, R.; Piras, G.; Fiamma, M.; Monne, M. I.; Fancello, T.; Milia, J.; Orru, S.; Scognamiglio, S.; Serra, C.; Mameli, G.; Uzzau, S.; Orru, G.; Palmas, A. D.; Rubino, S.; Tramontano, E. | JOURNAL OF INFECTION AND PUBLIC HEALTH | - |
| The Stability of Social and Behavioral Rhythms and Unexpected Low Rate of Relevant Depressive Symptoms in Old Adults during the COVID-19 Pandemic | 1-gen-2024 | Sancassiani, Federica; Cossu, Giulia; Cantone, Elisa; Romano, Ferdinando; Perra, Alessandra; Urban, Antonio; Pinna, Samantha; Del Giacco, Stefano; Littera, Roberto; Firinu, Davide; Chessa, Luchino; Tramontano, Enzo; Nardi, Antonio Egidio; Carta, Mauro Giovanni | JOURNAL OF CLINICAL MEDICINE | - |
| 5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action | 1-gen-2023 | Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication | 1-gen-2023 | Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B. | VIRUSES | - |
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1-gen-2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Comparing the responses of countries and National Health Systems to the COVID-19 pandemic: a critical analysis with a case-report series | 1-gen-2023 | Carta, M. G.; Orru, G.; Littera, R.; Firinu, D.; Chessa, L.; Cossu, G.; Primavera, D.; DEL GIACCO, S.; Tramontano, E.; Manocchio, N.; Buonomo, C.; Scano, A. | EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | - |
| DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action | 1-gen-2023 | Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello | VIRUSES | - |
| Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity | 1-gen-2023 | Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F. | MOLECULES | - |
| Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication | 1-gen-2023 | Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action | 1-gen-2023 | Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M | ANTIVIRAL RESEARCH | - |
| HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) | 1-gen-2023 | Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca | PHARMACEUTICALS | - |
| Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages | 1-gen-2023 | Grandi, Nicole; Erbì, Maria Chiara; Scognamiglio, Sante; Tramontano, Enzo | MICROBIOLOGY SPECTRUM | - |
| Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome | 1-gen-2023 | Scognamiglio, Sante; Grandi, Nicole; Pessiu, Eleonora; Tramontano, Enzo | VIRUS RESEARCH | - |
| Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus | 1-gen-2023 | Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |