DEPLANO, ALESSANDRO
DEPLANO, ALESSANDRO
A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists
2014-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Negri, L; Lattanzi, R; Balboni, Gianfranco
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors
2020-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors
2019-01-01 Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina
Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor
2015-01-01 Gouveia Figueira, S; Karlsson, J; Deplano, Alessandro; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; Congiu, Cenzo; Onnis, Valentina; Fowler, Cj
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions
2017-01-01 Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones
2016-01-01 Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J.
Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents
2014-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Demurtas, M; Balboni, Gianfranco
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents
2021-01-01 Deplano, Alessandro; Karlsson, Jessica; Moraca, Federica; Svensson, Mona; Cristiano, Claudia; Morgillo, Carmine Marco; Fowler, Christopher J.; Russo, Roberto; Catalanotti, Bruno; Onnis, Valentina
DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS
2016-01-01 Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique; Onnis, Valentina
Design, synthesis and pharmacological investigation on new FAAH inhibitors
2014-01-01 Onnis, Valentina; Congiu, Cenzo; Deplano, Alessandro; Demurtas, M; Cipriano, M; Fowler C., J; Morgillo C., M; Catalanotti, B.
Design, synthesis and SAR of small molecules acting on pain pathways
2016-03-24
Development and Validation of Molecular Overlays Derived from Three-Dimensional Hydrophobic Similarity with PharmScreen
2018-01-01 Vázquez, J.; Deplano, A.; Herrero, A.; Ginex, T.; Gibert, E.; Rabal, O.; Oyarzabal, J.; Herrero, E.; Luque, F. J.
Dihydroquinazoline and Triazinedione Derivatives as Prok1 and Prok2 receptor antagonists in HEK-293 transfected cells
2015-01-01 Balboni, Gianfranco; Congiu, Cenzo; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Sbai, Oualid; Rondard, Philippe; Onnis, Valentina
DIHYDROQUINAZOLINE BENZYLAMIDES AS ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE INHIBITORS
2016-01-01 Onnis, Valentina; Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Catto, Marco; Pisani, Leonardo; Carotti, Angelo
Discovery of a novel class of profen derivatives as FAAH inhibitors: MD and QM/MM studies of the binding mode and 3D SAR
2016-01-01 Morgillo, Cm; Deplano, Alessandro; Karlsson, J; Cipriano, M; Björklund, E; Fowler, Cj; Onnis, Valentina; Luque, Fj; Catalanotti, B.
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen
2020-01-01 Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization
2014-01-01 Lattanzi, R; Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Francioso, A; Ambrosio, C; Casella, I; Costa, T; Caltabiano, G; Matsoukas M., T; Balboni, Gianfranco; Negri, L.
Homology modeling of a Class A GPCR in the inactive conformation: A quantitative analysis of the correlation between model/template sequence identity and model accuracy
2016-01-01 Costanzi, Stefano; Skorski, Matthew; Deplano, Alessandro; Habermehl, Brett; Mendoza, Mary; Wang, Keyun; Biederman, Michelle; Dawson, Jessica; Gaoa, Jia
Hydrophobic similarity between molecules: Application to three-dimensional molecular overlays with PharmScreen
2018-01-01 Vazquez, Javier; Deplano, Alessandro; Herrero, Albert; Gibert, Enric; Ginex, Tiziana; Rabal, Obdulia; Oyarzabal, Julen; Herrero, Enric; Luque, F Javier
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis
2015-01-01 Eloh, Kodjo; Demurtas, Monica; Deplano, Alessandro; Ngoutane Mfopa, A; Murgia, Antonio; Maxia, Andrea; Onnis, Valentina; Caboni, Pierluigi
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists | 1-gen-2014 | Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Negri, L; Lattanzi, R; Balboni, Gianfranco | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors | 1-gen-2020 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors | 1-gen-2019 | Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor | 1-gen-2015 | Gouveia Figueira, S; Karlsson, J; Deplano, Alessandro; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; Congiu, Cenzo; Onnis, Valentina; Fowler, Cj | PLOS ONE | - |
| Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions | 1-gen-2017 | Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo | PATHOGENS AND DISEASE | - |
| Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones | 1-gen-2016 | Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J. | MOLECULES | - |
| Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents | 1-gen-2014 | Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Demurtas, M; Balboni, Gianfranco | CHEMMEDCHEM | - |
| Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents | 1-gen-2021 | Deplano, Alessandro; Karlsson, Jessica; Moraca, Federica; Svensson, Mona; Cristiano, Claudia; Morgillo, Carmine Marco; Fowler, Christopher J.; Russo, Roberto; Catalanotti, Bruno; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS | 1-gen-2016 | Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique; Onnis, Valentina | - | - |
| Design, synthesis and pharmacological investigation on new FAAH inhibitors | 1-gen-2014 | Onnis, Valentina; Congiu, Cenzo; Deplano, Alessandro; Demurtas, M; Cipriano, M; Fowler C., J; Morgillo C., M; Catalanotti, B. | CHEMMEDCHEM | - |
| Design, synthesis and SAR of small molecules acting on pain pathways | 24-mar-2016 | - | - | Università degli Studi di Cagliari |
| Development and Validation of Molecular Overlays Derived from Three-Dimensional Hydrophobic Similarity with PharmScreen | 1-gen-2018 | Vázquez, J.; Deplano, A.; Herrero, A.; Ginex, T.; Gibert, E.; Rabal, O.; Oyarzabal, J.; Herrero, E.; Luque, F. J. | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - |
| Dihydroquinazoline and Triazinedione Derivatives as Prok1 and Prok2 receptor antagonists in HEK-293 transfected cells | 1-gen-2015 | Balboni, Gianfranco; Congiu, Cenzo; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Sbai, Oualid; Rondard, Philippe; Onnis, Valentina | - | - |
| DIHYDROQUINAZOLINE BENZYLAMIDES AS ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE INHIBITORS | 1-gen-2016 | Onnis, Valentina; Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Catto, Marco; Pisani, Leonardo; Carotti, Angelo | - | - |
| Discovery of a novel class of profen derivatives as FAAH inhibitors: MD and QM/MM studies of the binding mode and 3D SAR | 1-gen-2016 | Morgillo, Cm; Deplano, Alessandro; Karlsson, J; Cipriano, M; Björklund, E; Fowler, Cj; Onnis, Valentina; Luque, Fj; Catalanotti, B. | - | - |
| Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen | 1-gen-2020 | Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization | 1-gen-2014 | Lattanzi, R; Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Francioso, A; Ambrosio, C; Casella, I; Costa, T; Caltabiano, G; Matsoukas M., T; Balboni, Gianfranco; Negri, L. | INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | - |
| Homology modeling of a Class A GPCR in the inactive conformation: A quantitative analysis of the correlation between model/template sequence identity and model accuracy | 1-gen-2016 | Costanzi, Stefano; Skorski, Matthew; Deplano, Alessandro; Habermehl, Brett; Mendoza, Mary; Wang, Keyun; Biederman, Michelle; Dawson, Jessica; Gaoa, Jia | JOURNAL OF MOLECULAR GRAPHICS & MODELLING | - |
| Hydrophobic similarity between molecules: Application to three-dimensional molecular overlays with PharmScreen | 1-gen-2018 | Vazquez, Javier; Deplano, Alessandro; Herrero, Albert; Gibert, Enric; Ginex, Tiziana; Rabal, Obdulia; Oyarzabal, Julen; Herrero, Enric; Luque, F Javier | - | American Chemical Society |
| In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis | 1-gen-2015 | Eloh, Kodjo; Demurtas, Monica; Deplano, Alessandro; Ngoutane Mfopa, A; Murgia, Antonio; Maxia, Andrea; Onnis, Valentina; Caboni, Pierluigi | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |