ZINZULA, LUCA
ZINZULA, LUCA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function
2023-01-01 Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production
2022-01-01 Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay
2018-01-01 Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo
Insights into Ebola VP35 oligomerization from molecular simulations
2018-01-01 DI PALMA, Francesco; Ramaswamy, VENKATA KRISHNAN; Daino, Gianluca; Frau, Aldo; Corona, Angela; Zinzula, Luca; Tramontano, Enzo; Ruggerone, Paolo; Vargiu, ATTILIO VITTORIO
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein
2018-01-01 Ramaswamy, VENKATA KRISHNAN; DI PALMA, Francesco; Vargiu, Attilio V.; Corona, Angela; Piano, Dario; Ruggerone, Paolo; Zinzula, Luca; Tramontano, Enzo
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach
2013-01-01 Costi, R; Métifiot, M; Esposito, Francesca; Cuzzucoli Crucitti, G; Pescatori, L; Messore, A; Scipione, L; Tortorella, S; Zinzula, Luca; Novellino, E; Pommier, Y; Tramontano, Enzo; Marchand, C; Di Santo, R.
Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit
2013-01-01 Zinzula, Luca; Tramontano, Enzo
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35
2012-01-01 Zinzula, Luca; Esposito, Francesca; Pala, D; Tramontano, Enzo
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach
2012-01-01 Distinto, Simona; Esposito, Francesca; Kirchmair, J; Cardia, MARIA CRISTINA; Gaspari, M; Maccioni, Elias; Alcaro, S; Markt, P; Wolber, G; Zinzula, Luca; Tramontano, Enzo
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function
2012-01-01 Esposito, Francesca; Corona, Angela; Zinzula, Luca; Kharlamova, Tatyana; Tramontano, Enzo
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases
2011-01-01 Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo
Bycatch of large elasmobranchs in the traditional tuna traps (tonnare) of Sardinia from 1990 to 2009
2011-01-01 Storai, T; Zinzula, Luca; Repetto, S; Zuffa, M; Morgan, A; Mandelman, J.
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35
2011-01-01 Zinzula, Luca; Esposito, Francesca; Pala, D; Tramontano, Enzo
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities
2011-01-01 Tramontano, Enzo; Kharlamova, T; Zinzula, Luca; Esposito, Francesca
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach
2011-01-01 Distinto, S; Esposito, Francesca; Kirchmair, J; Cardia, Cm; Maccioni, Elias; Alcaro, S; Zinzula, Luca; Tramontano, Enzo
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds
2011-01-01 Esposito, Francesca; Zinzula, Luca; Maxia, Andrea; Tramontano, Enzo; Sanna, Cinzia
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs
2010-01-01 Esposito, F.; Kharlamova, T.; Distinto, S.; Zinzula, L.; Cheng, Y-C.; Dutschman, G.; Floris, G.; Markt, P.; Tramontano, E.
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs
2010-01-01 Esposito, F; Kharlamova, T.; Distinto, S.; Zinzula, L.; Floris, G.; Sanna Randaccio, L.; Deutschman, G.; Cheng, Y-C.; Tramontano, E.
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata
2009-01-01 Bicchi, C; Rubiolo, P; Ballero, Mauro; Sanna, Cinzia; Matteodo, M; Esposito, Francesca; Zinzula, Luca; Tramontano, Enzo
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives
2009-01-01 Kharlamova, T; Esposito, Francesca; Zinzula, Luca; Floris, G; Cheng, Yc; Dutschman, Ge; Tramontano, Enzo
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function | 1-gen-2023 | Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca | VIRUS RESEARCH | - |
| Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production | 1-gen-2022 | Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay | 1-gen-2018 | Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo | BIOCHEMISTRY | - |
| Insights into Ebola VP35 oligomerization from molecular simulations | 1-gen-2018 | DI PALMA, Francesco; Ramaswamy, VENKATA KRISHNAN; Daino, Gianluca; Frau, Aldo; Corona, Angela; Zinzula, Luca; Tramontano, Enzo; Ruggerone, Paolo; Vargiu, ATTILIO VITTORIO | ABSTRACTS OF PAPERS - AMERICAN CHEMICAL SOCIETY | AMER CHEMICAL SOC |
| Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein | 1-gen-2018 | Ramaswamy, VENKATA KRISHNAN; DI PALMA, Francesco; Vargiu, Attilio V.; Corona, Angela; Piano, Dario; Ruggerone, Paolo; Zinzula, Luca; Tramontano, Enzo | VIRUS RESEARCH | - |
| 6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach | 1-gen-2013 | Costi, R; Métifiot, M; Esposito, Francesca; Cuzzucoli Crucitti, G; Pescatori, L; Messore, A; Scipione, L; Tortorella, S; Zinzula, Luca; Novellino, E; Pommier, Y; Tramontano, Enzo; Marchand, C; Di Santo, R. | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit | 1-gen-2013 | Zinzula, Luca; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 | 1-gen-2012 | Zinzula, Luca; Esposito, Francesca; Pala, D; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach | 1-gen-2012 | Distinto, Simona; Esposito, Francesca; Kirchmair, J; Cardia, MARIA CRISTINA; Gaspari, M; Maccioni, Elias; Alcaro, S; Markt, P; Wolber, G; Zinzula, Luca; Tramontano, Enzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function | 1-gen-2012 | Esposito, Francesca; Corona, Angela; Zinzula, Luca; Kharlamova, Tatyana; Tramontano, Enzo | CHEMOTHERAPY | - |
| Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases | 1-gen-2011 | Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo | THE FEBS JOURNAL | - |
| Bycatch of large elasmobranchs in the traditional tuna traps (tonnare) of Sardinia from 1990 to 2009 | 1-gen-2011 | Storai, T; Zinzula, Luca; Repetto, S; Zuffa, M; Morgan, A; Mandelman, J. | FISHERIES RESEARCH | - |
| dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 | 1-gen-2011 | Zinzula, Luca; Esposito, Francesca; Pala, D; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities | 1-gen-2011 | Tramontano, Enzo; Kharlamova, T; Zinzula, Luca; Esposito, Francesca | JOURNAL OF CHEMOTHERAPY | - |
| Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach | 1-gen-2011 | Distinto, S; Esposito, Francesca; Kirchmair, J; Cardia, Cm; Maccioni, Elias; Alcaro, S; Zinzula, Luca; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds | 1-gen-2011 | Esposito, Francesca; Zinzula, Luca; Maxia, Andrea; Tramontano, Enzo; Sanna, Cinzia | NATURAL PRODUCT RESEARCH | - |
| Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs | 1-gen-2010 | Esposito, F.; Kharlamova, T.; Distinto, S.; Zinzula, L.; Cheng, Y-C.; Dutschman, G.; Floris, G.; Markt, P.; Tramontano, E. | - | - |
| Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs | 1-gen-2010 | Esposito, F; Kharlamova, T.; Distinto, S.; Zinzula, L.; Floris, G.; Sanna Randaccio, L.; Deutschman, G.; Cheng, Y-C.; Tramontano, E. | - | - |
| HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata | 1-gen-2009 | Bicchi, C; Rubiolo, P; Ballero, Mauro; Sanna, Cinzia; Matteodo, M; Esposito, Francesca; Zinzula, Luca; Tramontano, Enzo | PLANTA MEDICA | - |
| Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives | 1-gen-2009 | Kharlamova, T; Esposito, Francesca; Zinzula, Luca; Floris, G; Cheng, Yc; Dutschman, Ge; Tramontano, Enzo | MEDICINAL CHEMISTRY | - |