ESPOSITO, FRANCESCA

ESPOSITO, FRANCESCA  

DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE  

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Titolo Data di pubblicazione Autore(i) Rivista Editore
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex 1-gen-2024 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea VIRUS RESEARCH -
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action 1-gen-2023 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY -
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 1-gen-2023 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1-gen-2023 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello VIRUSES -
Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity 1-gen-2023 Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F. MOLECULES -
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) 1-gen-2023 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca PHARMACEUTICALS -
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 1-gen-2023 Fumagalli, Valeria; Di Lucia, Pietro; Ravà, Micol; Marotta, Davide; Bono, Elisa; Grassi, Stefano; Donnici, Lorena; Cannalire, Rolando; Stefanelli, Irina; Ferraro, Anastasia; Esposito, Francesca; Pariani, Elena; Inverso, Donato; Montesano, Camilla; Delbue, Serena; Perlman, Stanley; Tramontano, Enzo; De Francesco, Raffaele; Summa, Vincenzo; Guidotti, Luca G; Iannacone, Matteo EMBO MOLECULAR MEDICINE -
Special Issue “Advances in Antiviral Agents against SARS-CoV-2 and Its Variants” 1-gen-2023 Esposito, Francesca VIRUSES -
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1-gen-2023 Biolatti, Matteo; Blangetti, Marco; Baggieri, Melissa; Marchi, Antonella; Gioacchini, Silvia; Bajetto, Greta; Arnodo, Davide; Bucci, Paola; Fioravanti, Raoul; Kojouri, Maedeh; Bersani, Matteo; D’Arrigo, Giulia; Siragusa, Lydia; Ghinato, Simone; De Andre, Marco; Gugliesi, Francesca; Albano, Camilla; Pasquero, Selina; Visentin, Ivan; D’Ugo, Emilio; Esposito, Francesca; Malune, Paolo; Tramontano, Enzo; Prandi, Cristina; Spyrakis, Francesca; Magurano, Fabio; Dell’Oste, Valentina ACS INFECTIOUS DISEASES -
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 1-gen-2023 Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And JOURNAL OF CHEMICAL INFORMATION AND MODELING -
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1-gen-2022 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter SCIENTIFIC DATA -
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 1-gen-2022 Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana ACS MEDICINAL CHEMISTRY LETTERS -
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 1-gen-2022 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1-gen-2022 Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE -
RiV4PoC: A high effective microbicidal coating for high-touch surfaces 1-gen-2022 Angius, Fabrizio; Scano, Alessandra; Esposito, Francesca; Ennas, Guido; Manzin, Aldo - -
ANTIBACTERIAL COATING 1-gen-2021 Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio - -
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata 1-gen-2021 Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida MOLECULES -
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1-gen-2021 Meleddu, Rita; Corona, Angela; Distinto, Simona; Cottiglia, Filippo; Deplano, Serenella; Sequeira, Lisa; Secci, Daniela; Onali, Alessia; Sanna, Erica; Esposito, Francesca; Cirone, Italo; Ortuso, Francesco; Alcaro, Stefano; Tramontano, Enzo; Mátyus, Péter; Maccioni, Elias MOLECULES -
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1-gen-2021 Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE -
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1-gen-2021 Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F. PLANTS -