ESPOSITO, FRANCESCA
ESPOSITO, FRANCESCA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase
2015-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication
2020-01-01 Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function
2011-01-01 Meleddu, Rita; Corona, Angela; Distinto, Simona; Esposito, Francesca; Sanna, M. L.; Cardia, C.; Tramontano, Enzo; Maccioni, Elias
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
2023-01-01 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E.
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach
2013-01-01 Costi, R; Métifiot, M; Esposito, Francesca; Cuzzucoli Crucitti, G; Pescatori, L; Messore, A; Scipione, L; Tortorella, S; Zinzula, Luca; Novellino, E; Pommier, Y; Tramontano, Enzo; Marchand, C; Di Santo, R.
6-[1-(4-fluorophenyl)methyl-1H-pyrrol-2-y1)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro
2005-01-01 Tramontano, Enzo; Esposito, Francesca; Badas, R; DI SANTO, R; Costi, R; La, Colla
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives
2014-01-01 Corona, Angela; Cosconati, S; Tierry, S; Pescatore, L; Di Leva F., S; Subra, F.; Delelis, O; Esposito, Francesca; Costi, R; Novellino, E; Di Santo, R; Tramontano, E.
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase.
2011-01-01 Esposito, Francesca; Distinto, Simona; J., Kirchmair; C. M., Cardia; Maccioni, Elias; S., Alcaro; L., Zinzula; E., Tramontano
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75
2014-01-01 Esposito, Francesca; Tramontano, Enzo
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β
2015-01-01 Cannas, V; Daino, Gl; Corona, Angela; Esposito, Francesca; Tramontano, Enzo
A novel assay for the screening of antiviral agents targeted to viral proteins involved in dsRNA binding-mediated inhibition of innate immunity
2012-01-01 Luca, Zinzula; Esposito, Francesca; Daniela, Pala; Enzo, Tramontano
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs
2010-01-01 Esposito, F.; Kharlamova, T.; Distinto, S.; Zinzula, L.; Cheng, Y-C.; Dutschman, G.; Floris, G.; Markt, P.; Tramontano, E.
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs
2010-01-01 Esposito, F; Kharlamova, T.; Distinto, S.; Zinzula, L.; Floris, G.; Sanna Randaccio, L.; Deutschman, G.; Cheng, Y-C.; Tramontano, E.
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases
2011-01-01 Esposito, Francesca; Kharlamova, T; Distinto, Simona; Zinzula, Luca; Cheng Y., C; Dutschman, G; Floris, G; Markt, P; Corona, Angela; Tramontano, Enzo
An efficient route to novel uracil-based drug-like molecules
2015-01-01 Babkov, Da; Chizhov, Ao; Khandazhinskaya, Al; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; SELEY RADTKE, Kl; Novikov, Ms
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum.
2012-01-01 Sanna, Cinzia; Esposito, Francesca; Del Vecchio, C; Mandas, D; Ballero, Mauro; Bianco, A; Parolin, C; Tramontano, Enzo
ANTIBACTERIAL COATING
2021-01-01 Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio
Antiviral drug discovery: HIV-1 RNase H, the next hit target
2007-01-01 Esposito, Francesca; Zinzula, L.; Tramontano, Enzo
Biochemical characterization of the dsRNA binding by wild and mutant Ebola virus innate immunity suppressor VP35 protein.
2011-01-01 Luca, Zinzula; Esposito, Francesca; Daniela, Pala; Enzo, Tramontano
Biological activities of aerial parts extracts of Euphorbia characias
2016-01-01 Pisano, MARIA BARBARA; Cosentino, Sofia; Viale, Silvia; Spano', Delia; Corona, Angela; Esposito, Francesca; Tramontano, Enzo; Montoro, P; Tuberoso, CARLO IGNAZIO GIOVANNI; Medda, Rosaria; Pintus, Francesca