MOI, DAVIDE
MOI, DAVIDE
Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors
2024-01-01 Moi, Davide; Vittorio, Serena; Angeli, Andrea; Supuran, Claudiu T.; Onnis, Valentina
Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 Mpro
2023-01-01 Citarella, Andrea; Moi, Davide; Pedrini, Martina; Pérez-Peña, Helena; Pieraccini, Stefano; Stagno, Claudio; Micale, Nicola; Schirmeister, Tanja; Sibille, Giulia; Gribaudo, Giorgio; Silvani, Alessandra; Passarella, Daniele; Giannini, Clelia
Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors
2023-01-01 Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses
2023-01-01 Citarella, Andrea; Moi, Davide; Pedrini, Martina; Pérez-Peña, Helena; Pieraccini, Stefano; Dimasi, Alessandro; Stagno, Claudio; Micale, Nicola; Schirmeister, Tanja; Sibille, Giulia; Gribaudo, Giorgio; Silvani, Alessandra; Giannini, Clelia; Passarella, Daniele
Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity
2023-01-01 Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Continuous-Flow Synthesis of Arylthio-Cyclopropyl Carbonyl Compounds
2022-01-01 Moi, Davide; Cabua, Maria Chiara; Velichko, Viktoria; Cocco, Andrea; Chiappone, Annalisa; Mocci, Rita; Porcu, Stefania; Piras, Monica; Bianco, Stefano; Pesciaioli, Fabio; Secci, Francesco
Dual Targeting Strategies on Histone Deacetylase 6 (HDAC6) and Heat Shock Protein 90 (Hsp90)
2022-01-01 Bonanni, Davide; Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bergamini, Elisa; Rastelli, Giulio
Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives
2022-01-01 Dettori, Tinuccia; Sanna, Giuseppina; Cocco, Andrea; Serreli, Gabriele; Deiana, Monica; Palmas, Vanessa; Onnis, Valentina; Pilia, Luca; Melis, Nicola; Moi, Davide; Caria, Paola; Secci, Francesco
Synthesis of potent and selective HDAC6 inhibitors led to unexpected opening of a quinazoline ring
2022-01-01 Moi, Davide; Citarella, Andrea; Bonanni, Davide; Pinzi, Luca; Passarella, Daniele; Silvani, Alessandra; Giannini, Clelia; Rastelli, Giulio
Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications
2021-01-01 Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bonanni, Davide; Rastelli, Giulio
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group
2021-01-01 Linciano, Pasquale; Pinzi, Luca; Belluti, Silvia; Chianese, Ugo; Benedetti, Rosaria; Moi, Davide; Altucci, Lucia; Franchini, Silvia; Imbriano, Carol; Sorbi, Claudia; Rastelli, Giulio
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors
2020-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Monopharmacology, polypharmacology and PROTAC approaches in drug discovery: investigation of enzyme inhibitors and antioxidant compounds
2020-02-06
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors
2020-01-01 Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones
2019-01-01 Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated
2019-01-01 Géraldy, Magalie; Morgen, Michael; Sehr, Peter; Steimbach, Raphael; Moi, Davide; Ridinger, Johannes; Oehme, Ina; Witt, Olaf; Malz, Mona; Nogueira, Mauro S; Koch, Oliver; Gunkel, Nikolas; Miller, Aubry K
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation
2019-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors
2019-01-01 Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors | 1-gen-2024 | Moi, Davide; Vittorio, Serena; Angeli, Andrea; Supuran, Claudiu T.; Onnis, Valentina | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 Mpro | 1-gen-2023 | Citarella, Andrea; Moi, Davide; Pedrini, Martina; Pérez-Peña, Helena; Pieraccini, Stefano; Stagno, Claudio; Micale, Nicola; Schirmeister, Tanja; Sibille, Giulia; Gribaudo, Giorgio; Silvani, Alessandra; Passarella, Daniele; Giannini, Clelia | MOLECULES | - |
| Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors | 1-gen-2023 | Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses | 1-gen-2023 | Citarella, Andrea; Moi, Davide; Pedrini, Martina; Pérez-Peña, Helena; Pieraccini, Stefano; Dimasi, Alessandro; Stagno, Claudio; Micale, Nicola; Schirmeister, Tanja; Sibille, Giulia; Gribaudo, Giorgio; Silvani, Alessandra; Giannini, Clelia; Passarella, Daniele | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
| Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity | 1-gen-2023 | Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| Continuous-Flow Synthesis of Arylthio-Cyclopropyl Carbonyl Compounds | 1-gen-2022 | Moi, Davide; Cabua, Maria Chiara; Velichko, Viktoria; Cocco, Andrea; Chiappone, Annalisa; Mocci, Rita; Porcu, Stefania; Piras, Monica; Bianco, Stefano; Pesciaioli, Fabio; Secci, Francesco | MOLECULES | - |
| Dual Targeting Strategies on Histone Deacetylase 6 (HDAC6) and Heat Shock Protein 90 (Hsp90) | 1-gen-2022 | Bonanni, Davide; Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bergamini, Elisa; Rastelli, Giulio | CURRENT MEDICINAL CHEMISTRY | - |
| Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives | 1-gen-2022 | Dettori, Tinuccia; Sanna, Giuseppina; Cocco, Andrea; Serreli, Gabriele; Deiana, Monica; Palmas, Vanessa; Onnis, Valentina; Pilia, Luca; Melis, Nicola; Moi, Davide; Caria, Paola; Secci, Francesco | MOLECULES | - |
| Synthesis of potent and selective HDAC6 inhibitors led to unexpected opening of a quinazoline ring | 1-gen-2022 | Moi, Davide; Citarella, Andrea; Bonanni, Davide; Pinzi, Luca; Passarella, Daniele; Silvani, Alessandra; Giannini, Clelia; Rastelli, Giulio | RSC ADVANCES | - |
| Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications | 1-gen-2021 | Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bonanni, Davide; Rastelli, Giulio | ACS OMEGA | - |
| Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group | 1-gen-2021 | Linciano, Pasquale; Pinzi, Luca; Belluti, Silvia; Chianese, Ugo; Benedetti, Rosaria; Moi, Davide; Altucci, Lucia; Franchini, Silvia; Imbriano, Carol; Sorbi, Claudia; Rastelli, Giulio | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors | 1-gen-2020 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives | 1-gen-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | PHARMACEUTICALS | - |
| Monopharmacology, polypharmacology and PROTAC approaches in drug discovery: investigation of enzyme inhibitors and antioxidant compounds | 6-feb-2020 | - | - | Università degli Studi di Cagliari |
| Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 1-gen-2020 | Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles | 1-gen-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones | 1-gen-2019 | Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated | 1-gen-2019 | Géraldy, Magalie; Morgen, Michael; Sehr, Peter; Steimbach, Raphael; Moi, Davide; Ridinger, Johannes; Oehme, Ina; Witt, Olaf; Malz, Mona; Nogueira, Mauro S; Koch, Oliver; Gunkel, Nikolas; Miller, Aubry K | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation | 1-gen-2019 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors | 1-gen-2019 | Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |