DETTORI, LAURA
DETTORI, LAURA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Cyclization-Inspired Structural Optimization: Designing Potent Non-nucleoside Reverse Transcriptase Inhibitors with Enhanced Safety and Selectivity
2026-01-01 Zhang, Y. -X.; Pannecouque, C.; Clercq, E. D.; Tramontano, E.; Corona, A.; Dettori, L.; Tran, P. -T.; Li, X. -D.; Su, S.; Wang, S.; Chen, F. -E.
Rational structure-based design and optimization of next-generation biphenyl-piperidine-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors
2026-01-01 Zhang, Kun; Zhao, Li-Min; Xing, Tianhao; Bu, Yueyue; Wang, Qingyun; Pannecouque, Christophe; De Clercq, Erik; Corona, Angela; Dettori, Laura; Tramontano, Enzo; Wang, Shuai; Chen, Fen-Er
Scaffold hopping yields novel furo[3,2-d]pyrimidine NNRTIs with optimized antiviral potency, enhanced selectivity, and reduced hERG liability
2026-01-01 Zhang, Y. -X.; Pannecouque, C.; De Clercq, E.; Tramontano, E.; Corona, A.; Dettori, L.; Tran, P. -T.; Li, X. -D.; Su, S.; Wang, S.; Chen, F. -E.
Design, Synthesis and Biological Evaluation of 3-Hydrazonoindolin-2-one Derivatives as Novel HIV-1 RNase H Inhibitors
2025-01-01 Zhang, Yiying; Wang, Rao; Bu, Yueyue; Corona, Angela; Dettori, Laura; Tramontano, Enzo; Pannecouque, Christophe; De Clercq, Erik; Wang, Shuai; Meng, Ge; Chen, Fen-Er
Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability
2025-01-01 Zhang, K.; Xing, T.; Ding, L.; Pannecouque, C.; De Clercq, E.; Corona, A.; Dettori, L.; Tramontano, E.; Wang, S.; Chen, F. -E.
Structure-Based Discovery of Novel Diarylpyrimidines as Potent and Selective Non-Nucleoside Reverse Transcriptase Inhibitors: From CH(CN)-Biphenyl-Diarylpyrimidines to C=NNH2-Biphenyl-Diarylpyrimidines
2025-01-01 Chen, Xiao-Mei; Pannecouque, Christophe; De Clercq, Erik; Lian, Yu-Xuan; Corona, Angela; Dettori, Laura; Tramontano, Enzo; Wang, Shuai; Chen, Fen-Er
Association of VDR Polymorphisms with Muscle Mass Development in Elite Young Soccer Players: A Pilot Study
2024-01-01 Flore, Laura; Robledo, Renato; Dettori, Laura; Scorcu, Marco; Francalacci, Paolo; Tocco, Filippo; Massidda, Myosotis; Calò, Carla Maria