Nome |
# |
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay, file e2f56ed8-3c40-3eaf-e053-3a05fe0a5d97
|
924
|
Insights into Ebola Virus VP35 and VP24 Interferon inhibitory functions and their initial exploitation as drug targets, file e2f56ed8-266c-3eaf-e053-3a05fe0a5d97
|
710
|
Ribonuclease H, an unexploited target for antiviral intervention against HIV and hepatitis B virus, file e2f56ed8-c678-3eaf-e053-3a05fe0a5d97
|
671
|
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions, file e2f56ed7-ec87-3eaf-e053-3a05fe0a5d97
|
607
|
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors, file e2f56ed7-b882-3eaf-e053-3a05fe0a5d97
|
551
|
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques, file e2f56ed7-d7cc-3eaf-e053-3a05fe0a5d97
|
543
|
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops, file e2f56ed7-ade3-3eaf-e053-3a05fe0a5d97
|
458
|
1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity, file e2f56ed9-1aa1-3eaf-e053-3a05fe0a5d97
|
393
|
Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity, file e2f56ed8-9ede-3eaf-e053-3a05fe0a5d97
|
373
|
Meeting report: 32nd International Conference on Antiviral Research, file e2f56ed8-d698-3eaf-e053-3a05fe0a5d97
|
349
|
HERV envelope proteins: Physiological role and pathogenic potential in cancer and autoimmunity, file e2f56ed7-8c73-3eaf-e053-3a05fe0a5d97
|
327
|
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci, file e2f56ed9-2188-3eaf-e053-3a05fe0a5d97
|
297
|
Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses, file e2f56ed7-bdc3-3eaf-e053-3a05fe0a5d97
|
231
|
HERV-W group evolutionary history in non-human primates: Characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini, file e2f56ed7-246f-3eaf-e053-3a05fe0a5d97
|
229
|
RNA-seq transcriptome analysis reveals long terminal repeat retrotransposon modulation in human peripheral blood mononuclear cells after in vivo lipopolysaccharide injection, file e2f56ed9-62b2-3eaf-e053-3a05fe0a5d97
|
215
|
Classification and characterization of human endogenous retroviruses; mosaic forms are common, file e2f56ed4-ed4a-3eaf-e053-3a05fe0a5d97
|
208
|
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives, file e2f56ed4-ea17-3eaf-e053-3a05fe0a5d97
|
203
|
The S-layer protein DR_2577 binds deinoxanthin and under desiccation conditions protects against UV-radiation in Deinococcus radiodurans, file e2f56ed4-f56e-3eaf-e053-3a05fe0a5d97
|
200
|
Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS), file e2f56ed8-4e8e-3eaf-e053-3a05fe0a5d97
|
195
|
Ebola virus VP35 blocks stress granule assembly, file e2f56ed6-748a-3eaf-e053-3a05fe0a5d97
|
192
|
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives, file e2f56ed4-eab0-3eaf-e053-3a05fe0a5d97
|
180
|
Contribution of type W human endogenous retroviruses to the human genome: Characterization of HERV-W proviral insertions and processed pseudogenes, file e2f56ed5-9386-3eaf-e053-3a05fe0a5d97
|
180
|
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans, file e2f56ed4-760f-3eaf-e053-3a05fe0a5d97
|
179
|
5-arylaminouracil derivatives as potential dual-action agents, file e2f56ed5-34b0-3eaf-e053-3a05fe0a5d97
|
175
|
Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology, file e2f56ed6-9e7e-3eaf-e053-3a05fe0a5d97
|
174
|
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors, file e2f56ed5-36fb-3eaf-e053-3a05fe0a5d97
|
172
|
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors, file e2f56eda-c47e-3eaf-e053-3a05fe0a5d97
|
152
|
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6, file e2f56ed5-3c4f-3eaf-e053-3a05fe0a5d97
|
139
|
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase, file e2f56ed6-c1d3-3eaf-e053-3a05fe0a5d97
|
138
|
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase, file e2f56ed5-3595-3eaf-e053-3a05fe0a5d97
|
137
|
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication, file e2f56ed7-819e-3eaf-e053-3a05fe0a5d97
|
137
|
Natural and Nature-Derived Products Targeting Human Coronaviruses, file e2f56ed9-a738-3eaf-e053-3a05fe0a5d97
|
134
|
The emerging field of human endogenous retroviruses: Understanding their physiological role and contribution to diseases, file e2f56ed8-8698-3eaf-e053-3a05fe0a5d97
|
131
|
Broad-range potential of Asphodelus microcarpus leaves extract for drug development, file e2f56ed6-b31d-3eaf-e053-3a05fe0a5d97
|
130
|
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain, file e2f56ed6-5d51-3eaf-e053-3a05fe0a5d97
|
125
|
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion, file e2f56ed7-0941-3eaf-e053-3a05fe0a5d97
|
124
|
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication, file e2f56eda-a012-3eaf-e053-3a05fe0a5d97
|
123
|
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition, file e2f56ed8-9801-3eaf-e053-3a05fe0a5d97
|
122
|
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function, file e2f56ed9-4627-3eaf-e053-3a05fe0a5d97
|
118
|
Contribution of human retroviruses to disease development-A focus on the HIV- And HERV-cancer relationships and treatment strategies, file e2f56ed9-7c32-3eaf-e053-3a05fe0a5d97
|
118
|
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities, file e2f56ed5-4495-3eaf-e053-3a05fe0a5d97
|
117
|
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase, file e2f56ed9-b9fe-3eaf-e053-3a05fe0a5d97
|
111
|
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H, file e2f56ed9-70ec-3eaf-e053-3a05fe0a5d97
|
107
|
Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport, file e2f56ed3-8921-3eaf-e053-3a05fe0a5d97
|
105
|
High-Throughput Sequencing is a Crucial Tool to Investigate the Contribution of Human Endogenous Retroviruses (HERVs) to Human Biology and Development, file e2f56ed8-ee52-3eaf-e053-3a05fe0a5d97
|
105
|
Development and validation of a novel dual luciferase reporter gene assay to quantify Ebola virus VP24 inhibition of IFN signaling, file e2f56ed7-63db-3eaf-e053-3a05fe0a5d97
|
103
|
Biological activities of aerial parts extracts of Euphorbia characias, file e2f56ed5-7e31-3eaf-e053-3a05fe0a5d97
|
99
|
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata, file e2f56eda-2734-3eaf-e053-3a05fe0a5d97
|
94
|
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture, file e2f56ed9-9ba0-3eaf-e053-3a05fe0a5d97
|
92
|
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication, file e2f56ed8-ef23-3eaf-e053-3a05fe0a5d97
|
81
|
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity, file 365c76e3-371b-4c83-bad3-3733586012f5
|
80
|
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach, file c3cdaef4-4af2-44e2-b75e-815b1f4465a6
|
80
|
null, file e2f56ed9-8083-3eaf-e053-3a05fe0a5d97
|
79
|
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2, file e2f56ed9-fed3-3eaf-e053-3a05fe0a5d97
|
78
|
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities, file e2f56eda-4279-3eaf-e053-3a05fe0a5d97
|
72
|
Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds, file 88a34b18-0a5d-4596-a9d1-c82ceba21930
|
70
|
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase, file 6ab46032-462e-47f0-bffe-1cded7d2e748
|
67
|
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route, file def774fa-3ac8-40e7-abdc-0714228d24cb
|
65
|
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants, file e2f56ed9-05dc-3eaf-e053-3a05fe0a5d97
|
64
|
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions, file e2f56eda-222c-3eaf-e053-3a05fe0a5d97
|
60
|
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome, file 58f98b2b-da53-4457-ae3d-74789477efe7
|
58
|
HIV-1 Reverse Transcriptase still remains a new drug target: Structure, Function, Classical inhibitors and new inhibitors with innovative mechanism of action, file e2f56ed3-9855-3eaf-e053-3a05fe0a5d97
|
58
|
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase, file e04e01a7-d295-4712-b05a-1faf6cc4ad84
|
54
|
Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS), file e2f56ed8-4e8f-3eaf-e053-3a05fe0a5d97
|
54
|
Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates, file e2f56ed9-5d3c-3eaf-e053-3a05fe0a5d97
|
49
|
A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the Copper Age, file e2f56ed9-a371-3eaf-e053-3a05fe0a5d97
|
45
|
INMI1 Zika Virus NS4B Antagonizes the Interferon Signaling by Suppressing STAT1 Phosphorylation, file e2f56eda-7b5e-3eaf-e053-3a05fe0a5d97
|
45
|
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity, file e2f56eda-d9b8-3eaf-e053-3a05fe0a5d97
|
44
|
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors, file e2f56ed8-1f4f-3eaf-e053-3a05fe0a5d97
|
40
|
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923, file e2f56ed9-74e6-3eaf-e053-3a05fe0a5d97
|
40
|
Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action, file 509260bf-755c-42b4-8509-6236de2ae627
|
38
|
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain, file e2f56eda-ac16-3eaf-e053-3a05fe0a5d97
|
33
|
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination, file 0effbeee-38bd-4178-bd9e-0014730ca7c7
|
31
|
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function, file e2f56eda-0989-3eaf-e053-3a05fe0a5d97
|
30
|
Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors, file e2f56eda-7bfb-3eaf-e053-3a05fe0a5d97
|
30
|
Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages, file 8ea6c875-65a5-4d5b-8fd3-6b4ecfa04232
|
28
|
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function, file 8b81be09-576f-49ee-b25c-38ea85693939
|
27
|
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses, file 6b855124-992c-4c43-8ef2-855a76f51167
|
25
|
HERV‐K(HML7) integrations in the human genome: Comprehensive characterization and comparative analysis in non‐human primates, file e2f56eda-7bf7-3eaf-e053-3a05fe0a5d97
|
23
|
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions, file e2f56ed6-c3c4-3eaf-e053-3a05fe0a5d97
|
18
|
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase, file e2f56ed6-52ca-3eaf-e053-3a05fe0a5d97
|
17
|
Garcinol from Garcinia indica inhibits HIV-1 reverse transcriptase-associated ribonuclease H, file e2f56eda-0a0d-3eaf-e053-3a05fe0a5d97
|
17
|
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration, file 42c90c31-fd18-4f74-ab31-201875a566b9
|
16
|
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action, file 8362faad-16eb-4d5f-8845-2fa29ef1697b
|
14
|
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H, file e2f56eda-681a-3eaf-e053-3a05fe0a5d97
|
14
|
Retrotransposons as drivers of Mammalian brain evolution, file e2f56eda-7548-3eaf-e053-3a05fe0a5d97
|
14
|
The Methanolic Extract of Perilla frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry, file e2f56eda-3487-3eaf-e053-3a05fe0a5d97
|
13
|
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase, file e2f56ed3-8eb6-3eaf-e053-3a05fe0a5d97
|
12
|
1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity, file e2f56ed9-4969-3eaf-e053-3a05fe0a5d97
|
12
|
Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity, file e2f56eda-7d54-3eaf-e053-3a05fe0a5d97
|
12
|
Comparing the responses of countries
and National Health Systems
to the COVID-19 pandemic:
a critical analysis with a case-report series, file 8593ac91-8e25-4f2a-9edd-ee03aef561dd
|
11
|
Natural and Nature-Derived Products Targeting Human Coronaviruses, file e2f56ed9-a739-3eaf-e053-3a05fe0a5d97
|
11
|
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach, file aeba8af2-0f72-445e-9b31-6b55bae30301
|
10
|
A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity, file e2f56ed5-36f6-3eaf-e053-3a05fe0a5d97
|
10
|
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors, file e2f56ed3-b9f3-3eaf-e053-3a05fe0a5d97
|
9
|
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity, file e2f56ed8-bbb0-3eaf-e053-3a05fe0a5d97
|
9
|
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action, file 25d17fb2-9959-4c53-b5aa-50635e005829
|
8
|
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France), file acd42975-a84f-43d0-a7d6-2b0d54b2b3a4
|
8
|
Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes, file e2f56eda-602c-3eaf-e053-3a05fe0a5d97
|
8
|
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds, file e2f56eda-7f6d-3eaf-e053-3a05fe0a5d97
|
8
|
Totale |
13.496 |