BIANCO, GIULIA
BIANCO, GIULIA
DIPARTIMENTO DI SCIENZE DELLA VITA E DELL'AMBIENTE
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay
2018-01-01 Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors
2018-01-01 Melis, Claudia; Distinto, Simona; Bianco, Giulia; Meleddu, Rita; Cottiglia, Filippo; Fois, Benedetta; Taverna, Domenico; Angius, Rossella; Alcaro, Stefano; Ortuso, Francesco; Gaspari, Marco; Angeli, Andrea; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T.; Maccioni, Elias
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides
2018-01-01 Meleddu, Rita; Distinto, Simona; Cottiglia, Filippo; Angius, Rossella; Gaspari, Marco; Taverna, Domenico; Melis, Claudia; Angeli, Andrea; Bianco, Giulia; Deplano, Serenella; Fois, Benedetta; Del Prete, Sonia; Capasso, Clemente; Alcaro, Stefano; Ortuso, Francesco; Yanez, Matilde; Supuran Claudiu, T.; Maccioni, Elias
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions
2017-01-01 Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase
2017-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Tramontano, Enzo; Bianco, Giulia; Melis, Claudia; Cottiglia, Filippo; Maccioni, Elias
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors
2017-01-01 Melis, Claudia; Meleddu, Rita; Angeli, Andrea; Distinto, Simona; Bianco, Giulia; Capasso, Clemente; Cottiglia, Filippo; Angius, Rossella; Supuran, Claudiu T.; Maccioni, Elias
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms
2017-01-01 Bianco, Giulia; Meleddu, Rita; Distinto, Simona; Cottiglia, Filippo; Gaspari, Marco; Melis, Claudia; Corona, Angela; Angius, Rossella; Angeli, Andrea; Taverna, Domenico; Alcaro, Stefano; Leitans, Janis; Kazaks, Andris; Tars, Kaspars; Supuran, Claudiu T.; Maccioni, Elias
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders
2017-01-01 Fois, Benedetta; Bianco, Giulia; Sonar, Vijay P.; Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Melis, Claudia; Marras, Luisa; Pompei, Raffaello; Floris, Costantino; Caboni, Pierluigi; Cottiglia, Filippo
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B
2017-01-01 Meleddu, Rita; Distinto, Simona; Cirilli, Roberto; Alcaro, Stefano; Yanez, Matilde; Sanna, MARIA LUISA; Corona, Angela; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Maccioni, Elias
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold
2016-01-01 Distinto, Simona; Meleddu, Rita; Yanez, Matilde; Cirilli, Roberto; Bianco, Giulia; Sanna, MARIA LUISA; Arridu, Antonella; Cossu, Pietro; Cottiglia, Filippo; Faggi, Cristina; Ortuso, Francesco; Alcaro, Stefano; Maccioni, Elias
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida
2016-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Maccioni, Elias; Arridu, Antonella; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Sanna, Adriana; DE LOGU, Alessandro
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6
2016-01-01 Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Masaoka, T; Maccioni, Elias; Menéndez Arias, L; Alcaro, S; Le Grice, Sfj; Tramontano, Enzo
Structure-based approaches applied to the study of pharmaceutical relevant targets
2016-03-24
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase
2015-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII
2015-01-01 Meleddu, Rita; Maccioni, Elias; Distinto, Simona; Bianco, Giulia; Melis, Claudia; Alcaro, Stefano; Cottiglia, Filippo; Ceruso, Mariangela; Supuran, Claudiu T.
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents
2013-01-01 Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; DE LOGU, Alessandro; Matyus, P.; Maccioni, Elias
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents
2013-01-01 Meleddu, R.; Distinto, S; Sissi, C.; Musetti, C.; Arridu, A.; Bianco, Giulia; Parrotta, L.; Ortuso, F.; Alcaro, S.; Maccioni, Elias
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library
2013-01-01 Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; Bogdan, D.; Matyus, P.; Maccioni, Elias
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT
2013-01-01 Bianco, Giulia; Distinto, Simona; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias
MD protocol validation for the study of MAOB-inhibitor complexes
2013-01-01 Bianco, Giulia; Cossu, P.; Distinto, Simona; Meleddu, R.; Arridu, A.; Ortuso, F.; Alcaro, S.; Maccioni, Elias
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay | 1-gen-2018 | Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo | BIOCHEMISTRY | - |
| Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors | 1-gen-2018 | Melis, Claudia; Distinto, Simona; Bianco, Giulia; Meleddu, Rita; Cottiglia, Filippo; Fois, Benedetta; Taverna, Domenico; Angius, Rossella; Alcaro, Stefano; Ortuso, Francesco; Gaspari, Marco; Angeli, Andrea; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T.; Maccioni, Elias | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides | 1-gen-2018 | Meleddu, Rita; Distinto, Simona; Cottiglia, Filippo; Angius, Rossella; Gaspari, Marco; Taverna, Domenico; Melis, Claudia; Angeli, Andrea; Bianco, Giulia; Deplano, Serenella; Fois, Benedetta; Del Prete, Sonia; Capasso, Clemente; Alcaro, Stefano; Ortuso, Francesco; Yanez, Matilde; Supuran Claudiu, T.; Maccioni, Elias | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions | 1-gen-2017 | Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo | PATHOGENS AND DISEASE | - |
| Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase | 1-gen-2017 | Meleddu, Rita; Distinto, Simona; Corona, Angela; Tramontano, Enzo; Bianco, Giulia; Melis, Claudia; Cottiglia, Filippo; Maccioni, Elias | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors | 1-gen-2017 | Melis, Claudia; Meleddu, Rita; Angeli, Andrea; Distinto, Simona; Bianco, Giulia; Capasso, Clemente; Cottiglia, Filippo; Angius, Rossella; Supuran, Claudiu T.; Maccioni, Elias | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms | 1-gen-2017 | Bianco, Giulia; Meleddu, Rita; Distinto, Simona; Cottiglia, Filippo; Gaspari, Marco; Melis, Claudia; Corona, Angela; Angius, Rossella; Angeli, Andrea; Taverna, Domenico; Alcaro, Stefano; Leitans, Janis; Kazaks, Andris; Tars, Kaspars; Supuran, Claudiu T.; Maccioni, Elias | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders | 1-gen-2017 | Fois, Benedetta; Bianco, Giulia; Sonar, Vijay P.; Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Melis, Claudia; Marras, Luisa; Pompei, Raffaello; Floris, Costantino; Caboni, Pierluigi; Cottiglia, Filippo | JOURNAL OF NATURAL PRODUCTS | - |
| Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B | 1-gen-2017 | Meleddu, Rita; Distinto, Simona; Cirilli, Roberto; Alcaro, Stefano; Yanez, Matilde; Sanna, MARIA LUISA; Corona, Angela; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Maccioni, Elias | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold | 1-gen-2016 | Distinto, Simona; Meleddu, Rita; Yanez, Matilde; Cirilli, Roberto; Bianco, Giulia; Sanna, MARIA LUISA; Arridu, Antonella; Cossu, Pietro; Cottiglia, Filippo; Faggi, Cristina; Ortuso, Francesco; Alcaro, Stefano; Maccioni, Elias | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida | 1-gen-2016 | Meleddu, Rita; Distinto, Simona; Corona, Angela; Maccioni, Elias; Arridu, Antonella; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Sanna, Adriana; DE LOGU, Alessandro | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 | 1-gen-2016 | Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Masaoka, T; Maccioni, Elias; Menéndez Arias, L; Alcaro, S; Le Grice, Sfj; Tramontano, Enzo | PLOS ONE | - |
| Structure-based approaches applied to the study of pharmaceutical relevant targets | 24-mar-2016 | - | - | Università degli Studi di Cagliari |
| (3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase | 1-gen-2015 | Meleddu, Rita; Distinto, Simona; Corona, Angela; Bianco, Giulia; Cannas, Valeria; Esposito, Francesca; Artese, A; Alcaro, S; Matyus, P; Bogdan, D; Cottiglia, Filippo; Tramontano, Enzo; Maccioni, Elias | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII | 1-gen-2015 | Meleddu, Rita; Maccioni, Elias; Distinto, Simona; Bianco, Giulia; Melis, Claudia; Alcaro, Stefano; Cottiglia, Filippo; Ceruso, Mariangela; Supuran, Claudiu T. | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| 2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents | 1-gen-2013 | Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; DE LOGU, Alessandro; Matyus, P.; Maccioni, Elias | - | - |
| Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents | 1-gen-2013 | Meleddu, R.; Distinto, S; Sissi, C.; Musetti, C.; Arridu, A.; Bianco, Giulia; Parrotta, L.; Ortuso, F.; Alcaro, S.; Maccioni, Elias | - | - |
| In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library | 1-gen-2013 | Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; Bogdan, D.; Matyus, P.; Maccioni, Elias | - | - |
| Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT | 1-gen-2013 | Bianco, Giulia; Distinto, Simona; Meleddu, R.; Cannas, C.; Del Vecchio, C.; Cottiglia, Filippo; Alcaro, S.; Parolin, C.; Tramontano, Enzo; Maccioni, Elias | - | - |
| MD protocol validation for the study of MAOB-inhibitor complexes | 1-gen-2013 | Bianco, Giulia; Cossu, P.; Distinto, Simona; Meleddu, R.; Arridu, A.; Ortuso, F.; Alcaro, S.; Maccioni, Elias | - | - |