Programmable framework for automatic tuning of software applications

A target application is automatically tuned. A list of solutions for identified performance bottlenecks in a target application is retrieved from a storage device. A plurality of modules is executed to compute specific parameters for solutions contained in the list of solutions. A list of modification commands associated with specific parameters computed by the plurality of modules is generated. The list of modification commands associated with the specific parameters is appended to a command sequence list. The list of modification commands is implemented in the target application. Specific source code regions corresponding to the identified performance bottlenecks in the target application are automatically tuned using the implemented list of modification commands. Then, the tuned target application is stored in the storage device.