Purpose:To provide a quantitative comparison between the macular retina thickness (MRT) and the Humphrey visual field (HVF) 10-2 SITA-standard strategy parameters in glaucomatous patients. Methods:Retrospective statistical analysis of spectral domain optical coherence tomography macular cube scans 512x128 (Cirrus HD-OCT 4000, Carl Zeiss Meditec, Inc. , Dublin, CA) compared with HVF mean deviation (MD) and pattern standard deviation (PSD) in sixty eyes of thirty-six glaucomatous subjects. Abnormal MRT on OCT was defined as an average macular thickness value of any one of four quadrants to be less than 5% of normative database. Results:Eighteen (30% ) glaucomatous eyes showed an abnormal MRT. In patients with reduced MRT the mean was 236,8 μm, whereas in patients with normal MRT the mean was 264,3 μm. In eleven eyes with MRT reduction the average MD was -10,56 dB, and PSD was greater than 2,5 dB in seven of these eleven eyes. In 61% of glaucomatous patients there was a correlation between MRT and MD. Conclusions:In glaucomatous patients, OCT macular retinal thickness analysis may help in detecting the existence of a visual field defect
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