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From Fossils to Function: Exploring the Evolutionary And Functional Diversity Of HERV Envelope Proteins Across Primate Lineages

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections, passed down through the germline in a Mendelian manner. They are prevalent in vertebrates, making up about 8% of the human genome. The ERV genome typically includes four key protein-coding genes: gag, pro, pol, and env, flanked by long terminal repeats (LTRs). The env gene, responsible for virus entry into cells, has evolved under various selection pressures, leading to its significant role in the study of diseases ...

LA ACIDIFICAZIONE DEGLI OCEANI E IL DIRITTO INTERNAZIONALE

Ocean acidification is a global phenomenon caused by the absorption of atmospheric carbon dioxide (CO₂), leading to chemical alterations that severely impact marine ecosystems. Despite its ecological and socio-economic significance, there is no specific international legal regime that comprehensively addresses this issue. In this context, this thesis analyzes the regulation of ocean acidification within international law, examining the existing legal instruments and their relationship with th...

Intelligenza artificiale e amministrazione della Giustizia

This research investigates, also in light of the proclaimed need to improve the efficiency of civil justice and reduce the time of judicial processes, the margins of use of artificial intelligence systems within the judicial system, with regard both to the exercise of jurisdiction in the strict sense (i.e., the decision-making process) and to the administration of justice as a whole (i.e., the accessory judicial activities). Regarding the decisional activity of the judicial authority, the a...

Building Human Digital Twins through Natural Language Processing: From Conversations to Knowledge

Human Digital Twins (HDTs) are a revolutionary advancement in human-computer interaction, offering personalised digital representations of individual knowledge, behaviour, and preferences. These sophisticated systems face fundamental challenges in ensuring the reliable organisation and processing of extensive conversational data. This thesis presents an integrated framework that addresses these challenges through advanced topic modelling, natural language processing, and information verificat...

Development and Characterization of Flexible Double-Gate Organic Transistors for Sensing Applications

Organic electronics is the starting point of a new kind of technology that’s gained a lot of interest in the latest decades of the 20th century and continues now in the 21st century. The possibility to realize flexible devices in a large area gives this field of research a particular interest, since it opens the doors to a multitude of new possible applications. Particular interest has been given to the possible biological and biomedical aspects of such technology, thanks to the possibility ...

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