Theoretical Considerations for the Design of Magnetic Scaffolds for Bone Tumor Hyperthermia

The effectiveness and the quality of the hyperthermia treatment of bone tumors using magnetic implants can be improved. To date, several biocompatible biomaterials loaded with magnetic nanoparticles have been manufactured and characterized. However, the intrinsic parameters of the so-called magnetic scaffolds are not tuned to perform an optimum hyperthermia treatment. This work, for the firs time, deals with the theoretical modeling of bone tumor hyperthermia using magnetic scaffolds. The goal is to investigate the heating abilities of a synthetic, virtual set of potential implants. The analysis is oriented in identifying the most essential features and relevant parameters for providing unique, useful feedbacks, form an electromagnetic engineering point of view, to material scientists and clinicians.