The Omics and Pregnancy-Induced Complications: Gestational Diabetes and Metabolomics

Metabolomics is one of the newest "omics" sciences that provides a picture of the metabolism of an individual in both physiological and pathological conditions and during treatment administration. This is achieved through the analysis of metabolites present in biological fluids and tissue samples. This technology may help elucidate the yet-unknown pathophysiological mechanism of diseases and would allow improving diagnosis, treatment, and quality of life of patients. In the past years, there was an increase in the application of metabolomics in gynecology, neonatology, and pregnancy-induced complications such as gestational diabetes mellitus. In this paragraph, the authors reviewed the literature concerning the application of metabolomics in the investigation of gestational diabetes, summarized the most relevant findings, and hypothesized possible future utilizations of these discoveries in clinical practice.