Microwave hyperthermia as therapeutic modality in oncology can be the next breakthrough technology if translated properly to the clinical practice. For deep-seated tumors such as bone cancers, antennas and radiating sources fails in achieving therapeutic temperatures without overheating healthy tissues. In this framework, magnetic implant to be used as thermo-seeds exposed to a several kHz magnetic field were studied. So far, the possibility of using magneto-dielectric biocompatible implant for performing microwave hyperthermia was not studied. In this work, we propose a simplified mono-dimensional electromagnetic model to study the propagation in a multilayer structure by means of the wave-amplitude transmission method. The model is aimed at finding suitable properties of the bolus, to be used as matching medium, while determining a set of working frequency for performing an effective treatment using magnetic implants. Then, we investigate the temperature evolution to determine, preliminarily, the feasibility of this innovative treatment modality.

Preliminary Study of Bone Tumors Hyperthermia at Microwaves Using Magnetic Implants

Lodi, M. B.;Curreli, N.;Marongiu, E.;Mariani, L.;Fanti, A.;Mazzarella, G.
2022-01-01

Abstract

Microwave hyperthermia as therapeutic modality in oncology can be the next breakthrough technology if translated properly to the clinical practice. For deep-seated tumors such as bone cancers, antennas and radiating sources fails in achieving therapeutic temperatures without overheating healthy tissues. In this framework, magnetic implant to be used as thermo-seeds exposed to a several kHz magnetic field were studied. So far, the possibility of using magneto-dielectric biocompatible implant for performing microwave hyperthermia was not studied. In this work, we propose a simplified mono-dimensional electromagnetic model to study the propagation in a multilayer structure by means of the wave-amplitude transmission method. The model is aimed at finding suitable properties of the bolus, to be used as matching medium, while determining a set of working frequency for performing an effective treatment using magnetic implants. Then, we investigate the temperature evolution to determine, preliminarily, the feasibility of this innovative treatment modality.
2022
978-88-31299-04-6
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/344047
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