Modelling of Magnetic Scaffolds for RF Hyperthermia of Deep-Seated Tumors

Deep seated tumors are neoplasms grown in challenging sites that call for innovative interventional strategies. Thanks to the development of magnetic nanocomposite biomaterials, multifunctional electromagnetic-responsive thermoseeds, called magnetic scaffolds, can be used as hyperthermia agents to control the local recurrence rate of deep-seated cancers through radiofrequency (RF) heating. To achieve an effective and high-quality treatment, the planning through multiphysics simulations is mandatory. A computational framework for solving the coupled electromagnetic and thermal phenomena ruling the RF heating of magnetic scaffolds will be presented and used to study different biomaterials, physiopathological scenarios and applications.