Therapeutical compositions, having enhanced anti-HIV activity consisting of 2', 3'-didesoxy- adenosine and of substances inhibiting the adenosine-deaminase selected from the group consisting of 9-(erythro-2-hydroxy-3-nonyl) adenine (EHNA), 3-deaza-EHNA, coformycin, desoxycoformycin, 1-deaza-EHNA, 1, 3-dideaza-EHNA and 7-deaza-EHNA.
Therapeutical compositions having anti-HIV activity consisting of 2', 3'-didesoxyadenosine and substances inhibiting adenosine deaminase.
PANI, ALESSANDRA
1992-01-01
Abstract
Therapeutical compositions, having enhanced anti-HIV activity consisting of 2', 3'-didesoxy- adenosine and of substances inhibiting the adenosine-deaminase selected from the group consisting of 9-(erythro-2-hydroxy-3-nonyl) adenine (EHNA), 3-deaza-EHNA, coformycin, desoxycoformycin, 1-deaza-EHNA, 1, 3-dideaza-EHNA and 7-deaza-EHNA.
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