Sfoglia per Autore
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort
2022-01-01 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production
2022-01-01 Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
2022-01-01 Romeo, Isabella; Ambrosio, Francesca Alessandra; Costa, Giosuè; Corona, Angela; Alkhatib, Mohammad; Salpini, Romina; Lemme, Saverio; Vergni, Davide; Svicher, Valentina; Santoro, Maria Mercedes; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Artese, Anna; Alcaro, Stefano
Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
2022-01-01 Chabukswar, S.; Grandi, N.; Tramontano, E.
Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes
2022-01-01 Grandi, N.; Paglietti, B.; Cusano, R.; Ibba, G.; Lai, V.; Piu, C.; Angioj, F.; Serra, C.; Kelvin, D. J.; Tramontano, E.; Rubino, S.
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route
2022-01-01 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities
2022-01-01 Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration
2022-01-01 Richetta, Clémence; Subra, Frédéric; Malet, Isabelle; Leh, Hervé; Charpentier, Charlotte; Corona, Angela; Collin, Gilles; Descamps, Diane; Deprez, Eric; Parissi, Vincent; Calvez, Vincent; Tramontano, Enzo; Marcelin, Anne-Geneviève; Delelis, Olivier
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity
2022-01-01 Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana
ANTIBACTERIAL COATING
2021-01-01 Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2
2021-01-01 Fanunza, Elisa; Carletti, Fabrizio; Quartu, Marina; Grandi, Nicole; Ermellino, Laura; Milia, Jessica; Corona, Angela; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Tramontano, Enzo
Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l
2021-01-01 Costanzi, E.; Kuzikov, M.; Esposito, F.; Albani, S.; Demitri, N.; Giabbai, B.; Camasta, M.; Tramontano, E.; Rossetti, G.; Zaliani, A.; Storici, P.
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata
2021-01-01 Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida
Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity
2021-01-01 Pisano, M. P.; Grandi, N.; Tramontano, E.
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase
2021-01-01 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto
Inhibitors of Ebolavirus targeting innate immune evasion
2021-01-01 Paulis, A. L.; Corona, A.; Tramontano, E.
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds
2021-01-01 Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F.
Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships
2021-01-01 Grandi, N.; Tramontano, E.; Berkhout, B.
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen
2021-01-01 Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea
Early Diffusion of SARS-CoV-2 Infection in the Inner Area of the Italian Sardinia Island
2021-01-01 Piras, Giovanna; Grandi, Nicole; Monne, Maria; Asproni, Rosanna; Fancello, Tatiana; Fiamma, Maura; Mameli, Giuseppe; Casu, Gavino; lo Maglio, Iana; Palmas, Angelo D.; Tramontano, Enzo
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort | 1-gen-2022 | Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter | SCIENTIFIC DATA | - |
| Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production | 1-gen-2022 | Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach | 1-gen-2022 | Romeo, Isabella; Ambrosio, Francesca Alessandra; Costa, Giosuè; Corona, Angela; Alkhatib, Mohammad; Salpini, Romina; Lemme, Saverio; Vergni, Davide; Svicher, Valentina; Santoro, Maria Mercedes; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Artese, Anna; Alcaro, Stefano | MOLECULES | - |
| Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants | 1-gen-2022 | Chabukswar, S.; Grandi, N.; Tramontano, E. | FRONTIERS IN MICROBIOLOGY | - |
| Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes | 1-gen-2022 | Grandi, N.; Paglietti, B.; Cusano, R.; Ibba, G.; Lai, V.; Piu, C.; Angioj, F.; Serra, C.; Kelvin, D. J.; Tramontano, E.; Rubino, S. | FRONTIERS IN PUBLIC HEALTH | - |
| Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route | 1-gen-2022 | Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities | 1-gen-2022 | Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration | 1-gen-2022 | Richetta, Clémence; Subra, Frédéric; Malet, Isabelle; Leh, Hervé; Charpentier, Charlotte; Corona, Angela; Collin, Gilles; Descamps, Diane; Deprez, Eric; Parissi, Vincent; Calvez, Vincent; Tramontano, Enzo; Marcelin, Anne-Geneviève; Delelis, Olivier | JOURNAL OF VIROLOGY | - |
| Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity | 1-gen-2022 | Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana | ACS MEDICINAL CHEMISTRY LETTERS | - |
| ANTIBACTERIAL COATING | 1-gen-2021 | Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio | - | - |
| Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2 | 1-gen-2021 | Fanunza, Elisa; Carletti, Fabrizio; Quartu, Marina; Grandi, Nicole; Ermellino, Laura; Milia, Jessica; Corona, Angela; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Tramontano, Enzo | VIRULENCE | - |
| Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l | 1-gen-2021 | Costanzi, E.; Kuzikov, M.; Esposito, F.; Albani, S.; Demitri, N.; Giabbai, B.; Camasta, M.; Tramontano, E.; Rossetti, G.; Zaliani, A.; Storici, P. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata | 1-gen-2021 | Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida | MOLECULES | - |
| Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity | 1-gen-2021 | Pisano, M. P.; Grandi, N.; Tramontano, E. | BIOLOGY | - |
| Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase | 1-gen-2021 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Inhibitors of Ebolavirus targeting innate immune evasion | 1-gen-2021 | Paulis, A. L.; Corona, A.; Tramontano, E. | ANNUAL REPORTS IN MEDICINAL CHEMISTRY | - |
| In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds | 1-gen-2021 | Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F. | PLANTS | - |
| Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships | 1-gen-2021 | Grandi, N.; Tramontano, E.; Berkhout, B. | RETROVIROLOGY | - |
| Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen | 1-gen-2021 | Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| Early Diffusion of SARS-CoV-2 Infection in the Inner Area of the Italian Sardinia Island | 1-gen-2021 | Piras, Giovanna; Grandi, Nicole; Monne, Maria; Asproni, Rosanna; Fancello, Tatiana; Fiamma, Maura; Mameli, Giuseppe; Casu, Gavino; lo Maglio, Iana; Palmas, Angelo D.; Tramontano, Enzo | FRONTIERS IN MICROBIOLOGY | - |
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