DEVOTO, PAOLA
DEVOTO, PAOLA
DIPARTIMENTO DI SCIENZE BIOMEDICHE
Combined α2- and D2-receptor blockade activates noradrenergic and dopaminergic neurons, but extracellular dopamine in the prefrontal cortex is determined by uptake and release from noradrenergic terminals
2023-01-01 Sagheddu, Claudia; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi
The potent α2-adrenoceptor antagonist RS 79948 also inhibits dopamine D2 -receptors: Comparison with atipamezole and raclopride
2022-01-01 Frau, Roberto; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Sagheddu, Claudia; Siddi, Carlotta; Santoni, Michele; Carli, Marco; Gessa, Gian Luigi
Impaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation
2021-01-01 Bono, Federica; Mutti, Veronica; Devoto, Paola; Bolognin, Silvia; Schwamborn, Jens C.; Missale, Cristina; Fiorentini, Chiara
Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats
2021-01-01 Traccis, Francesco; Serra, Valeria; Sagheddu, Claudia; Congiu, Mauro; Saba, Pierluigi; Giua, Gabriele; Devoto, Paola; Frau, Roberto; Cheer, Joseph Francois; Melis, Miriam
Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex
2020-01-01 Devoto, Paola; Sagheddu, Claudia; Santoni, Michele; Flore, Giovanna; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi
5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
2019-01-01 Fanni, S; Scheggi, S; Rossi, F; Tronci, E; Traccis, F; Stancampiano, R; DE MONTIS, MARIA GRAZIELLA; Devoto, P; Gambarana, C; Bortolato, M; Frau, R; Carta, M
Dysfunctional mesocortical dopamine circuit at pre-adolescence is associated to aggressive behavior in MAO-A hypomorphic mice exposed to early life stress
2019-01-01 Frau, Roberto; Fanni, Silvia; Serra, Valeria; Simola, Nicola; Godar, Sean C.; Traccis, Francesco; Devoto, Paola; Bortolato, Marco; Melis, Miriam
Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation
2019-01-01 Godar, Sean C; Mosher, Laura J; Scheggi, Simona; Devoto, Paola; Moench, Kelly M; Strathman, Hunter J; Jones, Cori M; Frau, Roberto; Melis, Miriam; Gambarana, Carla; Wilkinson, Brent; Demontis, M Graziella; Fowler, Stephen C; Coba, Marcelo P; Wellman, Cara L; Shih, Jean C; Bortolato, Marco
Modulation of the Startle Response in REM Sleep Behavior Disorder
2019-01-01 Puligheddu, M; Figorilli, M; Fantini, Ml; Carta, M; Traccis, F; Frau, R; Devoto, P; Pani, D; Bortolato, M
Noradrenergic terminals are the primary source of α2-adrenoceptor mediated dopamine release in the medial prefrontal cortex
2019-01-01 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Scheggi, Simona; Mulas, Giovanna; Gambarana, Carla; Spiga, Saturnino; Gessa, Gian Luigi
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
2019-01-01 Frau, Roberto; Miczán, Vivien; Traccis, Francesco; Aroni, Sonia; Pongor, Csaba I; Saba, Pierluigi; Serra, Valeria; Sagheddu, Claudia; Fanni, Silvia; Congiu, Mauro; Devoto, Paola; Cheer, JOSEPH FRANCOIS RENE; Katona, Istvan; Melis, Miriam
Startle Reflex as a possible biomarker associated with REM sleep behavior disorders in the prodromal stage of Parkinson's disease
2019-01-01 Traccis, F; Puligheddu, M; Figorilli, M; Carta, M; Devoto, P; Giua, G; Fantini, Ml; Pani, D; Bortolato, M; Frau, R
The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson’s disease patients
2019-01-01 Nuzzo, T.; Punzo, D.; Devoto, P.; Rosini, E.; Paciotti, S.; Sacchi, S.; Li, Q.; Thiolat, M. -L.; Vega, C.; Carella, M.; Carta, M.; Gardoni, F.; Calabresi, P.; Pollegioni, L.; Bezard, E.; Parnetti, L.; Errico, F.; Usiello, A.
The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia
2019-01-01 De Felice, M.; Melis, M.; Aroni, S.; Muntoni, A. L.; Fanni, S.; Frau, R.; Devoto, P.; Pistis, M.
Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex
2018-01-01 Antinori, Silvia; Fattore, Liana; Saba, Pierluigi; Fratta, Walter; Gessa, Gian Luigi; Devoto, Paola
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons
2018-01-01 Bono, Federica; Savoia, Paola; Guglielmi, Adele; Gennarelli, Massimo; Piovani, Giovanna; Sigala, Sandra; Leo, Damiana; Espinoza, Stefano; Gainetdinov, Raul R.; Devoto, Paola; Spano, Pierfranco; Missale, Cristina; Fiorentini, Chiara
Fasting biases µ-opioid receptors toward β–arrestin2-dependent signaling in the accumbens shell
2017-01-01 Scheggi, S; Ferrari, A; Pelliccia, T; Devoto, Paola; De Montis, Mg; Gambarana, C.
Pramipexole enhances disadvantageous decision-making: Lack of relation to changes in phasic dopamine release
2017-01-01 Pes, Romina; Godar, Sean C; Fox, Andrew T; Burgeno, Lauren M; Strathman, Hunter J; Jarmolowicz, David P; Devoto, Paola; Levant, Beth; Phillips, Paul E; Fowler, Stephen C; Bortolato, Marco
The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson's disease
2017-01-01 Frau, Roberto; Paola, Savoia; Fanni, Silvia; Chiara, Fiorentini; Camino, Fidalgo; Tronci, Elisabetta; Stancampiano, Roberto; Meloni, Mario; Antonino, Cannas; Marrosu, Francesco; Marco, Bortolato; Devoto, Paola; Cristina, Missale; Carta, Manolo
The neurosteroidogenic enzyme 5α-reductase mediates psychotic-like complications of sleep deprivation
2017-01-01 Frau, Roberto; Bini, Valentina; Soggiu, Alessio; Scheggi, Simona; Pardu, Alessandra; Fanni, Silvia; Roncada, Paola; Puligheddu, MONICA MARIA FRANCESCA; Marrosu, Francesco; Caruso, Donatella; Devoto, Paola; Bortolato, Marco
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Combined α2- and D2-receptor blockade activates noradrenergic and dopaminergic neurons, but extracellular dopamine in the prefrontal cortex is determined by uptake and release from noradrenergic terminals | 1-gen-2023 | Sagheddu, Claudia; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi | FRONTIERS IN PHARMACOLOGY | - |
| The potent α2-adrenoceptor antagonist RS 79948 also inhibits dopamine D2 -receptors: Comparison with atipamezole and raclopride | 1-gen-2022 | Frau, Roberto; Devoto, Paola; Aroni, Sonia; Saba, Pierluigi; Sagheddu, Claudia; Siddi, Carlotta; Santoni, Michele; Carli, Marco; Gessa, Gian Luigi | NEUROPHARMACOLOGY | - |
| Impaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation | 1-gen-2021 | Bono, Federica; Mutti, Veronica; Devoto, Paola; Bolognin, Silvia; Schwamborn, Jens C.; Missale, Cristina; Fiorentini, Chiara | NEUROBIOLOGY OF AGING | - |
| Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats | 1-gen-2021 | Traccis, Francesco; Serra, Valeria; Sagheddu, Claudia; Congiu, Mauro; Saba, Pierluigi; Giua, Gabriele; Devoto, Paola; Frau, Roberto; Cheer, Joseph Francois; Melis, Miriam | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex | 1-gen-2020 | Devoto, Paola; Sagheddu, Claudia; Santoni, Michele; Flore, Giovanna; Saba, Pierluigi; Pistis, Marco; Gessa, Gian Luigi | FRONTIERS IN PHARMACOLOGY | - |
| 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction | 1-gen-2019 | Fanni, S; Scheggi, S; Rossi, F; Tronci, E; Traccis, F; Stancampiano, R; DE MONTIS, MARIA GRAZIELLA; Devoto, P; Gambarana, C; Bortolato, M; Frau, R; Carta, M | NEUROBIOLOGY OF DISEASE | - |
| Dysfunctional mesocortical dopamine circuit at pre-adolescence is associated to aggressive behavior in MAO-A hypomorphic mice exposed to early life stress | 1-gen-2019 | Frau, Roberto; Fanni, Silvia; Serra, Valeria; Simola, Nicola; Godar, Sean C.; Traccis, Francesco; Devoto, Paola; Bortolato, Marco; Melis, Miriam | NEUROPHARMACOLOGY | - |
| Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation | 1-gen-2019 | Godar, Sean C; Mosher, Laura J; Scheggi, Simona; Devoto, Paola; Moench, Kelly M; Strathman, Hunter J; Jones, Cori M; Frau, Roberto; Melis, Miriam; Gambarana, Carla; Wilkinson, Brent; Demontis, M Graziella; Fowler, Stephen C; Coba, Marcelo P; Wellman, Cara L; Shih, Jean C; Bortolato, Marco | NEUROPHARMACOLOGY | - |
| Modulation of the Startle Response in REM Sleep Behavior Disorder | 1-gen-2019 | Puligheddu, M; Figorilli, M; Fantini, Ml; Carta, M; Traccis, F; Frau, R; Devoto, P; Pani, D; Bortolato, M | MOVEMENT DISORDERS | - |
| Noradrenergic terminals are the primary source of α2-adrenoceptor mediated dopamine release in the medial prefrontal cortex | 1-gen-2019 | Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Scheggi, Simona; Mulas, Giovanna; Gambarana, Carla; Spiga, Saturnino; Gessa, Gian Luigi | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | - |
| Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone | 1-gen-2019 | Frau, Roberto; Miczán, Vivien; Traccis, Francesco; Aroni, Sonia; Pongor, Csaba I; Saba, Pierluigi; Serra, Valeria; Sagheddu, Claudia; Fanni, Silvia; Congiu, Mauro; Devoto, Paola; Cheer, JOSEPH FRANCOIS RENE; Katona, Istvan; Melis, Miriam | NATURE NEUROSCIENCE | - |
| Startle Reflex as a possible biomarker associated with REM sleep behavior disorders in the prodromal stage of Parkinson's disease | 1-gen-2019 | Traccis, F; Puligheddu, M; Figorilli, M; Carta, M; Devoto, P; Giua, G; Fantini, Ml; Pani, D; Bortolato, M; Frau, R | MOVEMENT DISORDERS | - |
| The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson’s disease patients | 1-gen-2019 | Nuzzo, T.; Punzo, D.; Devoto, P.; Rosini, E.; Paciotti, S.; Sacchi, S.; Li, Q.; Thiolat, M. -L.; Vega, C.; Carella, M.; Carta, M.; Gardoni, F.; Calabresi, P.; Pollegioni, L.; Bezard, E.; Parnetti, L.; Errico, F.; Usiello, A. | SCIENTIFIC REPORTS | - |
| The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia | 1-gen-2019 | De Felice, M.; Melis, M.; Aroni, S.; Muntoni, A. L.; Fanni, S.; Frau, R.; Devoto, P.; Pistis, M. | CNS NEUROSCIENCE & THERAPEUTICS | - |
| Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex | 1-gen-2018 | Antinori, Silvia; Fattore, Liana; Saba, Pierluigi; Fratta, Walter; Gessa, Gian Luigi; Devoto, Paola | ADDICTION BIOLOGY | - |
| Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons | 1-gen-2018 | Bono, Federica; Savoia, Paola; Guglielmi, Adele; Gennarelli, Massimo; Piovani, Giovanna; Sigala, Sandra; Leo, Damiana; Espinoza, Stefano; Gainetdinov, Raul R.; Devoto, Paola; Spano, Pierfranco; Missale, Cristina; Fiorentini, Chiara | MOLECULAR NEUROBIOLOGY | - |
| Fasting biases µ-opioid receptors toward β–arrestin2-dependent signaling in the accumbens shell | 1-gen-2017 | Scheggi, S; Ferrari, A; Pelliccia, T; Devoto, Paola; De Montis, Mg; Gambarana, C. | NEUROSCIENCE | - |
| Pramipexole enhances disadvantageous decision-making: Lack of relation to changes in phasic dopamine release | 1-gen-2017 | Pes, Romina; Godar, Sean C; Fox, Andrew T; Burgeno, Lauren M; Strathman, Hunter J; Jarmolowicz, David P; Devoto, Paola; Levant, Beth; Phillips, Paul E; Fowler, Stephen C; Bortolato, Marco | NEUROPHARMACOLOGY | - |
| The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson's disease | 1-gen-2017 | Frau, Roberto; Paola, Savoia; Fanni, Silvia; Chiara, Fiorentini; Camino, Fidalgo; Tronci, Elisabetta; Stancampiano, Roberto; Meloni, Mario; Antonino, Cannas; Marrosu, Francesco; Marco, Bortolato; Devoto, Paola; Cristina, Missale; Carta, Manolo | EXPERIMENTAL NEUROLOGY | - |
| The neurosteroidogenic enzyme 5α-reductase mediates psychotic-like complications of sleep deprivation | 1-gen-2017 | Frau, Roberto; Bini, Valentina; Soggiu, Alessio; Scheggi, Simona; Pardu, Alessandra; Fanni, Silvia; Roncada, Paola; Puligheddu, MONICA MARIA FRANCESCA; Marrosu, Francesco; Caruso, Donatella; Devoto, Paola; Bortolato, Marco | NEUROPSYCHOPHARMACOLOGY | - |