FIORILLO, EDOARDO
FIORILLO, EDOARDO
Overexpression of the cytokine BAFF and autoimmunity risk
2017-01-01 Steri, M; Orru', Valeria; Idda, Ml; Pitzalis, M.; Pala, Mauro; Zara, I; Sidore, C; Faà, V; Floris, M; Deiana, M; Asunis, I; Porcu, E; Mulas, A; Piras, Mg; Lobina, M; Lai, S; Marongiu, Mara; Serra, V; Marongiu, M; Sole, G; Busonero, Fabio; Maschio, A; Cusano, Roberto; Cuccuru, G; Deidda, Francesca; Poddie, F; Farina, Gabriele; Dei, M; Virdis, F; Olla, S; Satta, Ma; Pani, M; Delitala, A; Cocco, Eleonora; Frau, Jessica; Coghe, Giancarlo; Lorefice, Lorena; Fenu, Giuseppe; Ferrigno, P; Ban, M; Barizzone, N; Leone, M; Guerini, Fr; Piga, Matteo; Firinu, Davide; Kockum, I; Lima, B; Olsson, T; Alfredsson, L; Suarez, A; Carreira, Pe; Castillo Palma, Mj; Marcus, Jh; Congia, Mauro; Angius, Andrea; Melis, M; Gonzalez, A; Alarcón Riquelme, Me; Da Silva, Bm; Marchini, M; Danieli, Mg; DEL GIACCO, Stefano; Mathieu, Alessandro; Pani, A; Montgomery, Sb; Rosati, G; Hillert, ; J., Sawcer; S, ; D'Alfonso, S; Todd, Ja; Novembre, J; Abecasis, Gr; Whalen, MICHAEL BERNARD; Marrosu, MARIA GIOVANNA; Meloni, Alessandra; Sanna, S; Gorospe, M; Schlessinger, D; Fiorillo, Edoardo; Zoledziewska, M; Cucca, F.
Effects of aging and sex difference on immune-related phenotypes
2013-01-01 Sole, G; Orru', Valeria; Fiorillo, Edoardo; Steri, M; Dei, M; Lai, S; Virdis, F; Schlessinger, D; Cucca, F; Sanna, S.
Genetic variants regulating immune cell levels in health and disease
2013-01-01 Orru', Valeria; Steri, M; Sole, G; Sidore, C; Virdis, F; Dei, M; Lai, S; Zoledziewska, M; Busonero, F; Mulas, A; Floris, M; Mentzen, Wi; Urru, S; Olla, S; Marongiu, M; Piras, Mg; Lobina, M; Maschio, A; Pitzalis, M; Urru, Mf; Marcelli, M; Cusano, R; Deidda, F; Serra, V; Oppo, M; Pilu, R; Reinier, F; Berutti, R; Pireddu, L; Zara, I; Porcu, E; Kwong, A; Brennan, C; Tarrier, B; Lyons, R; Kang, Hm; Uzzau, S; Atzeni, R; Valentini, M; Firinu, Davide; Leoni, L; Rotta, G; Naitza, S; Angius, A; Congia, M; Whalen, Mb; Jones, Cm; Schlessinger, D; Abecasis, Gr; Fiorillo, Edoardo; Sanna, S; Cucca, F.
System and pathway analysis of variants associated with immune cell levels
2013-01-01 Mentzen, Wi; Floris, M.; Orru', Valeria; Ster, M; Sole, G; Urru, Sam; Olla, S; Virdis, F; Dei, M; Lai, S; Fiorillo, Edoardo; Sanna, S; Cucca, F.
A comprehensive phenotypic and genetic analysis of centenarians from 13 Villages located in the Sardinian region of Barbagia-Mandrolisai
2012-01-01 Urru, Sam; Ferreli, L; Zedda, G; N., Curreli; Piras, M; Lobina, M; Marongiu, M; Floris, M; Sanna, S; Orru', Valeria; Fiorillo, Edoardo; Galanello, R; Atzeni, A; Pani, A; Cucca, F.
Genetic factors associated with levels of immune cell types
2012-01-01 M., Steri; Orru', Valeria; Fiorillo, Edoardo; G., Sole; C., Sidore; F., Virdis; M., Dei; S., Lai; A., Mulas; M. G., Piras; M., Lobina; M., Marongiu; M., Zoledziewska; M., Congia; F., Busonero; A., Maschio; M. F., Urru; M., Marcelli; R., Atzeni; Firinu, Davide; M., Valentini; W., Mentzen; S., Naitza; M. B., Whalen; A., Angius; C. M., Jones; D., Schlessinger; G., Abecasis; S., Sanna; F., Cucca
Systematic assessment of the immune system by genetic mapping of its quantitative dimensions
2012-01-01 Sanna, S; Steri, M; Sole, G; Sidore, C; Urru, Mf; Busonero, F; Reinier, F; Dei, M; Lai, S; Virdis, F; Mulas, A; Marcelli, M; Atzeni, R; Angius, A; Jones, Cm; Schlessinger, D; Abecasis, Gr; Orru', Valeria; Fiorillo, Edoardo; Cucca, F.
Heritability and genetic mapping of hundreds of immune-related quantitative traits measured in a large Sardinian cohort
2011-01-01 Sanna, S; Sole, G; Steri, M; Dei, M; Lai, S; Virdis, F; Schlessinger, D; Congia, M; Naitza, S; Orru', Valeria; Fiorillo, Edoardo; Cucca, F.
Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue
2010-01-01 Fiorillo, Edoardo; Orru', Valeria; Stanford, Sm; Liu, Y; Salek, M; Rapini, N; Schenone, Ad; Saccucci, P; Delogu, Lg; Angelini, F; MANCA BITTI, Ml; Schmedt, C; Chan, Ac; Acuto, O; Bottini, N.
DAXX is a new AIRE-interacting protein
2010-01-01 Meloni, A; Fiorillo, Edoardo; Corda, D; Incani, Federica; Serra, Ml; Contini, Antonella; Cao, A; Rosatelli, MARIA CRISTINA
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus
2009-01-01 Orru', Valeria; Tsai, Sj; Rueda, B; Fiorillo, Edoardo; Stanford, Sm; Dasgupta, J; Hartiala, J; Zhao, L; ORTEGO CENTENO, N; D'Alfonso, S; ITALIAN COLLABORATIVE, Group; Arnett, Fc; Wu, H; GONZALEZ GAY, Ma; Tsao, Bp; PONS ESTEL, B; ALARCON RIQUELME, Me; He, Y; Zhang, Zy; Allayee, H; Chen, Xs; Martin, J; Bottini, N.
Autoimmune-associated LYP-W620 variant reduces T cell activation by altering a recirpocal feedback mechanism
2009-01-01 Fiorillo, Edoardo; Orru', Valeria; Liu, Y.; Stanford, S.; Salek, M.; Rapini, N.; Delogu, L.; Saccucci, P.; Angelini, F.; Manca Bitti, M.; Rosatelli, MARIA CRISTINA; Acuto, O.; Bottini, N.
Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation
2009-01-01 Tsai, Sj; Sen, U; Zhao, L; Greenleaf, Wb; Dasgupta, J; Fiorillo, Edoardo; Orru', Valeria; Bottini, N; Chen, Xs
Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain
2009-01-01 Liu, Y; Stanford, Sm; Jog, Sp; Fiorillo, Edoardo; Orru', Valeria; Comai, L; Bottini, N.
Whole-gene expression system by RMCE-mediated integration of PAC clones
2009-01-01 Orru', Valeria; Fiorillo, Edoardo; Stanford, S; Cucca, F; Bottini, N.
Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study
2008-01-01 Krishnamurthy, D; Karver, Mr; Fiorillo, Edoardo; Orru', Valeria; Stanford, Sm; Bottini, N; Barrios, Am
La variante proteica associata all’autoimmunità LYP-W620 riduce l’attivazione delle cellule T mediante l’alterazione della regolazione reciproca tra LYP ed Lck
2008-01-01 Fiorillo, Edoardo; Orru', Valeria; Liu, Y; Standford, S; Salek, M; Rapini, N; Delogu, L; Saccucci, P; Angelici, F; Bitti, Ml; Rosatelli, MARIA CRISTINA; Acuto, O; Bottini, N.
Functional Characterization of the Autoimmune-associated LYP-W620 Variant
2007-01-01 Zhao, L; Liu, Y; Fiorillo, Edoardo; Stanford, S; Orru', Valeria; Bottini, N.
Two novel mutations of the AIRE protein affecting its homodimerization properties
2005-01-01 Meloni, A; Fiorillo, Edoardo; Corda, D; Perniola, R; Cao, A; Rosatelli, MARIA CRISTINA
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Overexpression of the cytokine BAFF and autoimmunity risk | 1-gen-2017 | Steri, M; Orru', Valeria; Idda, Ml; Pitzalis, M.; Pala, Mauro; Zara, I; Sidore, C; Faà, V; Floris, M; Deiana, M; Asunis, I; Porcu, E; Mulas, A; Piras, Mg; Lobina, M; Lai, S; Marongiu, Mara; Serra, V; Marongiu, M; Sole, G; Busonero, Fabio; Maschio, A; Cusano, Roberto; Cuccuru, G; Deidda, Francesca; Poddie, F; Farina, Gabriele; Dei, M; Virdis, F; Olla, S; Satta, Ma; Pani, M; Delitala, A; Cocco, Eleonora; Frau, Jessica; Coghe, Giancarlo; Lorefice, Lorena; Fenu, Giuseppe; Ferrigno, P; Ban, M; Barizzone, N; Leone, M; Guerini, Fr; Piga, Matteo; Firinu, Davide; Kockum, I; Lima, B; Olsson, T; Alfredsson, L; Suarez, A; Carreira, Pe; Castillo Palma, Mj; Marcus, Jh; Congia, Mauro; Angius, Andrea; Melis, M; Gonzalez, A; Alarcón Riquelme, Me; Da Silva, Bm; Marchini, M; Danieli, Mg; DEL GIACCO, Stefano; Mathieu, Alessandro; Pani, A; Montgomery, Sb; Rosati, G; Hillert, ; J., Sawcer; S, ; D'Alfonso, S; Todd, Ja; Novembre, J; Abecasis, Gr; Whalen, MICHAEL BERNARD; Marrosu, MARIA GIOVANNA; Meloni, Alessandra; Sanna, S; Gorospe, M; Schlessinger, D; Fiorillo, Edoardo; Zoledziewska, M; Cucca, F. | NEW ENGLAND JOURNAL OF MEDICINE | - |
| Effects of aging and sex difference on immune-related phenotypes | 1-gen-2013 | Sole, G; Orru', Valeria; Fiorillo, Edoardo; Steri, M; Dei, M; Lai, S; Virdis, F; Schlessinger, D; Cucca, F; Sanna, S. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| Genetic variants regulating immune cell levels in health and disease | 1-gen-2013 | Orru', Valeria; Steri, M; Sole, G; Sidore, C; Virdis, F; Dei, M; Lai, S; Zoledziewska, M; Busonero, F; Mulas, A; Floris, M; Mentzen, Wi; Urru, S; Olla, S; Marongiu, M; Piras, Mg; Lobina, M; Maschio, A; Pitzalis, M; Urru, Mf; Marcelli, M; Cusano, R; Deidda, F; Serra, V; Oppo, M; Pilu, R; Reinier, F; Berutti, R; Pireddu, L; Zara, I; Porcu, E; Kwong, A; Brennan, C; Tarrier, B; Lyons, R; Kang, Hm; Uzzau, S; Atzeni, R; Valentini, M; Firinu, Davide; Leoni, L; Rotta, G; Naitza, S; Angius, A; Congia, M; Whalen, Mb; Jones, Cm; Schlessinger, D; Abecasis, Gr; Fiorillo, Edoardo; Sanna, S; Cucca, F. | CELL | - |
| System and pathway analysis of variants associated with immune cell levels | 1-gen-2013 | Mentzen, Wi; Floris, M.; Orru', Valeria; Ster, M; Sole, G; Urru, Sam; Olla, S; Virdis, F; Dei, M; Lai, S; Fiorillo, Edoardo; Sanna, S; Cucca, F. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| A comprehensive phenotypic and genetic analysis of centenarians from 13 Villages located in the Sardinian region of Barbagia-Mandrolisai | 1-gen-2012 | Urru, Sam; Ferreli, L; Zedda, G; N., Curreli; Piras, M; Lobina, M; Marongiu, M; Floris, M; Sanna, S; Orru', Valeria; Fiorillo, Edoardo; Galanello, R; Atzeni, A; Pani, A; Cucca, F. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| Genetic factors associated with levels of immune cell types | 1-gen-2012 | M., Steri; Orru', Valeria; Fiorillo, Edoardo; G., Sole; C., Sidore; F., Virdis; M., Dei; S., Lai; A., Mulas; M. G., Piras; M., Lobina; M., Marongiu; M., Zoledziewska; M., Congia; F., Busonero; A., Maschio; M. F., Urru; M., Marcelli; R., Atzeni; Firinu, Davide; M., Valentini; W., Mentzen; S., Naitza; M. B., Whalen; A., Angius; C. M., Jones; D., Schlessinger; G., Abecasis; S., Sanna; F., Cucca | - | - |
| Systematic assessment of the immune system by genetic mapping of its quantitative dimensions | 1-gen-2012 | Sanna, S; Steri, M; Sole, G; Sidore, C; Urru, Mf; Busonero, F; Reinier, F; Dei, M; Lai, S; Virdis, F; Mulas, A; Marcelli, M; Atzeni, R; Angius, A; Jones, Cm; Schlessinger, D; Abecasis, Gr; Orru', Valeria; Fiorillo, Edoardo; Cucca, F. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| Heritability and genetic mapping of hundreds of immune-related quantitative traits measured in a large Sardinian cohort | 1-gen-2011 | Sanna, S; Sole, G; Steri, M; Dei, M; Lai, S; Virdis, F; Schlessinger, D; Congia, M; Naitza, S; Orru', Valeria; Fiorillo, Edoardo; Cucca, F. | - | - |
| Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue | 1-gen-2010 | Fiorillo, Edoardo; Orru', Valeria; Stanford, Sm; Liu, Y; Salek, M; Rapini, N; Schenone, Ad; Saccucci, P; Delogu, Lg; Angelini, F; MANCA BITTI, Ml; Schmedt, C; Chan, Ac; Acuto, O; Bottini, N. | - | - |
| DAXX is a new AIRE-interacting protein | 1-gen-2010 | Meloni, A; Fiorillo, Edoardo; Corda, D; Incani, Federica; Serra, Ml; Contini, Antonella; Cao, A; Rosatelli, MARIA CRISTINA | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - |
| A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus | 1-gen-2009 | Orru', Valeria; Tsai, Sj; Rueda, B; Fiorillo, Edoardo; Stanford, Sm; Dasgupta, J; Hartiala, J; Zhao, L; ORTEGO CENTENO, N; D'Alfonso, S; ITALIAN COLLABORATIVE, Group; Arnett, Fc; Wu, H; GONZALEZ GAY, Ma; Tsao, Bp; PONS ESTEL, B; ALARCON RIQUELME, Me; He, Y; Zhang, Zy; Allayee, H; Chen, Xs; Martin, J; Bottini, N. | HUMAN MOLECULAR GENETICS | - |
| Autoimmune-associated LYP-W620 variant reduces T cell activation by altering a recirpocal feedback mechanism | 1-gen-2009 | Fiorillo, Edoardo; Orru', Valeria; Liu, Y.; Stanford, S.; Salek, M.; Rapini, N.; Delogu, L.; Saccucci, P.; Angelini, F.; Manca Bitti, M.; Rosatelli, MARIA CRISTINA; Acuto, O.; Bottini, N. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation | 1-gen-2009 | Tsai, Sj; Sen, U; Zhao, L; Greenleaf, Wb; Dasgupta, J; Fiorillo, Edoardo; Orru', Valeria; Bottini, N; Chen, Xs | BIOCHEMISTRY | - |
| Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain | 1-gen-2009 | Liu, Y; Stanford, Sm; Jog, Sp; Fiorillo, Edoardo; Orru', Valeria; Comai, L; Bottini, N. | BIOCHEMISTRY | - |
| Whole-gene expression system by RMCE-mediated integration of PAC clones | 1-gen-2009 | Orru', Valeria; Fiorillo, Edoardo; Stanford, S; Cucca, F; Bottini, N. | EUROPEAN JOURNAL OF HUMAN GENETICS | - |
| Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study | 1-gen-2008 | Krishnamurthy, D; Karver, Mr; Fiorillo, Edoardo; Orru', Valeria; Stanford, Sm; Bottini, N; Barrios, Am | JOURNAL OF MEDICINAL CHEMISTRY | - |
| La variante proteica associata all’autoimmunità LYP-W620 riduce l’attivazione delle cellule T mediante l’alterazione della regolazione reciproca tra LYP ed Lck | 1-gen-2008 | Fiorillo, Edoardo; Orru', Valeria; Liu, Y; Standford, S; Salek, M; Rapini, N; Delogu, L; Saccucci, P; Angelici, F; Bitti, Ml; Rosatelli, MARIA CRISTINA; Acuto, O; Bottini, N. | - | - |
| Functional Characterization of the Autoimmune-associated LYP-W620 Variant | 1-gen-2007 | Zhao, L; Liu, Y; Fiorillo, Edoardo; Stanford, S; Orru', Valeria; Bottini, N. | CLINICAL IMMUNOLOGY | - |
| Two novel mutations of the AIRE protein affecting its homodimerization properties | 1-gen-2005 | Meloni, A; Fiorillo, Edoardo; Corda, D; Perniola, R; Cao, A; Rosatelli, MARIA CRISTINA | HUMAN MUTATION | - |