A one-pot regioselective functionalization of 3-(methylsulfanyl)thiophene with different electrophiles at the 2- and 5-positions is reported. Proper selection of the experimental conditions allows the preparation of polysubstituted products not otherwise easily available.
A new versatile synthesis of 2,5-disubstituted 3-(methylsulfanyl)thiophenes
FATTUONI, CLAUDIA;USAI, MICHELE;CADONI, ENZO;CABIDDU, MARIA GRAZIA;
2008-01-01
Abstract
A one-pot regioselective functionalization of 3-(methylsulfanyl)thiophene with different electrophiles at the 2- and 5-positions is reported. Proper selection of the experimental conditions allows the preparation of polysubstituted products not otherwise easily available.File in questo prodotto:
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