An organic ultra-low voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows sub-nanometrical detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.
Ultra-Low Voltage, OTFT-Based Sensor for Label-Free DNA Detection
LAI, STEFANO;DEMELAS, MONIA;CASULA, GIULIA;COSSEDDU, PIERO;BARBARO, MASSIMO;BONFIGLIO, ANNALISA
2013-01-01
Abstract
An organic ultra-low voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows sub-nanometrical detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
DNA_LOW_VOLTAGE.pdf
Solo gestori archivio
Dimensione
806.92 kB
Formato
Adobe PDF
|
806.92 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I metadati presenti in IRIS UNICA sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono protetti da diritto d'autore, salvo diversa indicazione.
