An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction sequence.
Synthesis of functionalized tryptamines by Brønsted acid catalysed cascade reactions
MELIS, NICOLA;SECCI, FRANCESCO;FRONGIA, ANGELO
2015-01-01
Abstract
An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction sequence.
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