Herein we describe a novel and practical synthesis of the anti-HIV compound MC-1220. Through the use of inexpensive reagents and commercially available starting materials, MC-1220 and its analogues are more easily accessed by a four-step procedure involving a key reduction step.
A novel synthetic route for the anti-HIV drug MC-1220 and its analogues
LODDO, ROBERTA;
2010-01-01
Abstract
Herein we describe a novel and practical synthesis of the anti-HIV compound MC-1220. Through the use of inexpensive reagents and commercially available starting materials, MC-1220 and its analogues are more easily accessed by a four-step procedure involving a key reduction step.
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