Dehydroepiandrosterone, its sulfate and cognitive functions

De Menezes, Karina Junqueira; Peixoto, Clayton; Nardi, Antonio Egidio; Carta, Mauro; Machado, Sérgio; Veras, André Barciela

doi:10.2174/1745017901612010024

To present a review of cross-sectional and longitudinal studies that investigate the relationship between the hormones Dehydroepiandrosterone (DHEA) and Dehydroepiandrosterone sulfate (DHEA-S) and cognition. Methods: The cognition items included in this review were global cognitive function, memory, attention, executive function, intelligence, perception and visuospatial ability. A systematic review was proceeded using three databases: PubMed, ISI Web of Science, and PsycINFO. Results: Two thousand fifty five references about cognition and hormones were found; 772 duplicated references were excluded, resulting in 1.283 references to be evaluated. According to exclusion and inclusion criteria, 25 references were selected. A positive correlation between DHEA-S blood levels and global cognition was found in women and men. Other positive correlations between DHEA-S and working memory, attention and verbal fluency were found only in women. The DHEA effect on cognition is limited to one study conducted among young men with high-doses.

Dehydroepiandrosterone, its sulfate and cognitive functions / De Menezes, Karina Junqueira; Peixoto, Clayton; Nardi, Antonio Egidio; Carta, Mauro Giovanni; Machado, Sérgio; Veras, André Barciela. - 12:1-2(2016), pp. 24-37.

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Titolo:	Dehydroepiandrosterone, its sulfate and cognitive functions
Autori:	De Menezes, Karina Junqueira Peixoto, Clayton Nardi, Antonio Egidio CARTA, MAURO Machado, Sérgio Veras, André Barciela mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2016
Rivista:	CLINICAL PRACTICE AND EPIDEMIOLOGY IN MENTAL HEALTH
Citazione:	Dehydroepiandrosterone, its sulfate and cognitive functions / De Menezes, Karina Junqueira; Peixoto, Clayton; Nardi, Antonio Egidio; Carta, Mauro Giovanni; Machado, Sérgio; Veras, André Barciela. - 12:1-2(2016), pp. 24-37.
Handle:	http://hdl.handle.net/11584/175512
Tipologia:	1.1 Articolo in rivista

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