A novel approach for the electromechanical disruption analysis of the ITER Ion Cyclotron antenna is proposed. It is based on the use of the sub-modeling technique and can also be used for the analysis of other tokamak’s in-vessel and out-vessel components. The disruption phenomenon is simulated by using a Finite Element model of one ITER sector and by imposing the plasma current density decay. A subsequent detailed electromagnetic analysis of the antenna and of the neighbouring components is performed by using the sub-modeling technique considering as boundary conditions the results of the previous analysis. Finally a transient mechanical analysis is performed and stresses, displacements, forces, and torques applied in the antenna structure are computed.