The Gram-negative bacterium Fusobacterium nucleatum (Fn), is part of normal placental and oral microbiome, in particular tongue and dental plaque. In the same way, it is strictly associated with a set of diseases that increased in recent years: preterm birth, colorectal cancer, inflammatory bowel disease, periodontitis [1]. In the oral cavity, Fn concentration/growth results strictly related to human habits, such as alimentation and smoke. This research aims to determine the rate of this pathogen in oral biological samples (dental calculi) from 5,000 years ago to nowadays.
FUSOBACTERIUM NUCLEATUM IN CHILDREN’S ORAL CAVITY. A COMMENSAL TURNED PATHOGEN THAT INCREASED RADICALLY IN 5,000 YEARS.
Maria Paola ContuPrimo
Methodology
;Eleonora CasulaMethodology
;Giacomo PagliettiValidation
;Gloria DenottiMethodology
;Valentino GarauConceptualization
;Rossana MartorelliInvestigation
;Germano Orrù
Ultimo
Writing – Review & Editing
2018-01-01
Abstract
The Gram-negative bacterium Fusobacterium nucleatum (Fn), is part of normal placental and oral microbiome, in particular tongue and dental plaque. In the same way, it is strictly associated with a set of diseases that increased in recent years: preterm birth, colorectal cancer, inflammatory bowel disease, periodontitis [1]. In the oral cavity, Fn concentration/growth results strictly related to human habits, such as alimentation and smoke. This research aims to determine the rate of this pathogen in oral biological samples (dental calculi) from 5,000 years ago to nowadays.
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