This letter describes the 2-year follow-up of a 7-year-old girl with very-early-onset schizophrenia (VEOS), nonresponsive to risperidone and aripiprazole monotherapy and successfully treated with clozapine augmentation of aripiprazole.After drug-induced neutropenia, a rechallenge with aripiprazole–clozapine was made possible by adjunctive lithium carbonate, with a stable management of white blood cells (WBCs).
Clozapine-aripiprazole association in a 7-year-old girl with schizophrenia: clinical efficacy and successful management of neutropenia with lithium
Gagliano Antonella;
2009-01-01
Abstract
This letter describes the 2-year follow-up of a 7-year-old girl with very-early-onset schizophrenia (VEOS), nonresponsive to risperidone and aripiprazole monotherapy and successfully treated with clozapine augmentation of aripiprazole.After drug-induced neutropenia, a rechallenge with aripiprazole–clozapine was made possible by adjunctive lithium carbonate, with a stable management of white blood cells (WBCs).
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