A new Brønsted acid catalysed solvent-free cascade reaction consisting of a ring closure-ring fission process between α-arylaminocyclobutanones and alcohols has been established, providing highly functionalised 3-(2-alkoxyethyl)indoles in good to excellent yields.
Brønsted acid Catalysed Synthesis of 3-(2-Alkoxyethyl)indoles from α-Arylaminocyclobutanones and Alcohols
Serusi, LorenzoPrimo
;Luridiana, Alberto;Secci, Francesco;Caboni, Pierluigi;Frongia, Angelo
Ultimo
2019-01-01
Abstract
A new Brønsted acid catalysed solvent-free cascade reaction consisting of a ring closure-ring fission process between α-arylaminocyclobutanones and alcohols has been established, providing highly functionalised 3-(2-alkoxyethyl)indoles in good to excellent yields.
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