An original tandem reaction consisting of a thermal elimination-addition process was developed. Highly substituted β-sulfinyl cyclobutane carboxylic acid derivatives were obtained from isomeric α-sulfinyl derivatives in a single operation in good to high yields and with high trans diastereoselectivity.
Synthesis of β-sulfinyl cyclobutane carboxylic amides: Via a formal α to β sulphoxide migration process
Ghisu L.;Melis N.;Serusi L.;Luridiana A.;Soddu F.;Secci F.;Caboni P.;Frongia A.
Supervision
2019-01-01
Abstract
An original tandem reaction consisting of a thermal elimination-addition process was developed. Highly substituted β-sulfinyl cyclobutane carboxylic acid derivatives were obtained from isomeric α-sulfinyl derivatives in a single operation in good to high yields and with high trans diastereoselectivity.File in questo prodotto:
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