[reaction: see text] Efficient conversion of alcohols and‚-amino alcohols to the corresponding chlorides (and bromides) can be carried out at room temperaturein methylene chloride, using 2,4,6-trichloro[1,3,5]triazine andN,N-dimethyl formamide. This procedure can also be applied to optically activecarbinols.
An Efficent Route to Alkyl Chlorides from Alcohols Using the Complex TCT/DMF
PORCHEDDU, ANDREA
2002-01-01
Abstract
[reaction: see text] Efficient conversion of alcohols and‚-amino alcohols to the corresponding chlorides (and bromides) can be carried out at room temperaturein methylene chloride, using 2,4,6-trichloro[1,3,5]triazine andN,N-dimethyl formamide. This procedure can also be applied to optically activecarbinols.
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