A novel Bronsted acid catalyzed tandem reaction provides highly functionalized cyclobuta-fused tetrahydroquinoline carboxylic esters from anilines and 2-alkylenecyclobutanones in good to high yield. During the reaction a dynamic diastereoselective cyclization is achieved, resulting in the formation of three contiguous stereocenters with high stereoselectivity.
A Bronsted acid catalyzed tandem reaction for the diastereoselective synthesis of cyclobuta-fused tetrahydroquinoline carboxylic esters
Caboni, P;Secci, F;Frongia, A
2021-01-01
Abstract
A novel Bronsted acid catalyzed tandem reaction provides highly functionalized cyclobuta-fused tetrahydroquinoline carboxylic esters from anilines and 2-alkylenecyclobutanones in good to high yield. During the reaction a dynamic diastereoselective cyclization is achieved, resulting in the formation of three contiguous stereocenters with high stereoselectivity.File in questo prodotto:
File | Dimensione | Formato | |
---|---|---|---|
authorreprints.pdf
Solo gestori archivio
Descrizione: Articolo principale
Tipologia:
versione editoriale
Dimensione
1.79 MB
Formato
Adobe PDF
|
1.79 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
post print.pdf
Open Access dal 28/10/2022
Descrizione: Articolo principale
Tipologia:
versione post-print
Dimensione
838.37 kB
Formato
Adobe PDF
|
838.37 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.