Pregnancy represents an important event for women with multiple sclerosis (MS) and is often accompanied by post-partum disease reactivation. To date, the influence of this reproductive phase on long-term MS outcomes is still largely unexplored. The objective of the study was characterise a large real-world cohort of women with MS to evaluate the effects of pregnancy and breastfeeding on short- and long-term clinical and magnetic resonance imaging (MRI) outcomes while exploring the relationships with MRI measurements of brain atrophy.

Effects of Pregnancy and Breastfeeding on Clinical Outcomes and MRI Measurements of Women with Multiple Sclerosis: An Exploratory Real-World Cohort Study

Lorefice, Lorena
;
Fronza, Marzia;Fenu, Giuseppe;Frau, Jessica;Coghe, Giancarlo;D'Alterio, Maurizio Nicola;Angioni, Stefano;Cocco, Eleonora
2022

Abstract

Pregnancy represents an important event for women with multiple sclerosis (MS) and is often accompanied by post-partum disease reactivation. To date, the influence of this reproductive phase on long-term MS outcomes is still largely unexplored. The objective of the study was characterise a large real-world cohort of women with MS to evaluate the effects of pregnancy and breastfeeding on short- and long-term clinical and magnetic resonance imaging (MRI) outcomes while exploring the relationships with MRI measurements of brain atrophy.
Breastfeeding; Long-term MS outcomes; Multiple sclerosis; Post-partum; Pregnancy; Treatment optimisation
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11584/320673
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