The toxic naphthoquinone juglone (5-liydroxy-1,4-naphthoquitione) is efficiently degraded by the ligninolytic fungus Pleurotus sajor-caju, as demonstrated by the total bleaching within 9 d of a conventional liquid culture medium Supplemented with 0.6 mM juglone. The oxidative degradation involves the production of hydrogen peroxide arising from both enzymic and non-enzymic oxidation reactions, promoted by the fungus. Juglone is not directly attacked bv the oxidative enzymes of the ligninolytic machinery of P. saior-caju, such as laccase, manganese peroxidase and arvIalcohol oxidase. On the other hand, this naphthoquinone is a good substrate for a reductase, which triggers ail auto-oxidative process producing reactive oxygen species and leading to juglone degradation. The degradation process continues to completion by means of a direct, presumably non-catalysed reaction with hydrogen peroxide.

Degradation of juglone by Pleurotus sajor-caju

CURRELI, NICOLETTA;RESCIGNO, ANTONIO;SANJUST, ENRICO
2004

Abstract

The toxic naphthoquinone juglone (5-liydroxy-1,4-naphthoquitione) is efficiently degraded by the ligninolytic fungus Pleurotus sajor-caju, as demonstrated by the total bleaching within 9 d of a conventional liquid culture medium Supplemented with 0.6 mM juglone. The oxidative degradation involves the production of hydrogen peroxide arising from both enzymic and non-enzymic oxidation reactions, promoted by the fungus. Juglone is not directly attacked bv the oxidative enzymes of the ligninolytic machinery of P. saior-caju, such as laccase, manganese peroxidase and arvIalcohol oxidase. On the other hand, this naphthoquinone is a good substrate for a reductase, which triggers ail auto-oxidative process producing reactive oxygen species and leading to juglone degradation. The degradation process continues to completion by means of a direct, presumably non-catalysed reaction with hydrogen peroxide.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11584/32896
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