The toxic naphthoquinone juglone (5-liydroxy-1,4-naphthoquitione) is efficiently degraded by the ligninolytic fungus Pleurotus sajor-caju, as demonstrated by the total bleaching within 9 d of a conventional liquid culture medium Supplemented with 0.6 mM juglone. The oxidative degradation involves the production of hydrogen peroxide arising from both enzymic and non-enzymic oxidation reactions, promoted by the fungus. Juglone is not directly attacked bv the oxidative enzymes of the ligninolytic machinery of P. saior-caju, such as laccase, manganese peroxidase and arvIalcohol oxidase. On the other hand, this naphthoquinone is a good substrate for a reductase, which triggers ail auto-oxidative process producing reactive oxygen species and leading to juglone degradation. The degradation process continues to completion by means of a direct, presumably non-catalysed reaction with hydrogen peroxide.

Degradation of juglone by Pleurotus sajor-caju

CURRELI, NICOLETTA;RESCIGNO, ANTONIO;SANJUST, ENRICO
2004-01-01

Abstract

The toxic naphthoquinone juglone (5-liydroxy-1,4-naphthoquitione) is efficiently degraded by the ligninolytic fungus Pleurotus sajor-caju, as demonstrated by the total bleaching within 9 d of a conventional liquid culture medium Supplemented with 0.6 mM juglone. The oxidative degradation involves the production of hydrogen peroxide arising from both enzymic and non-enzymic oxidation reactions, promoted by the fungus. Juglone is not directly attacked bv the oxidative enzymes of the ligninolytic machinery of P. saior-caju, such as laccase, manganese peroxidase and arvIalcohol oxidase. On the other hand, this naphthoquinone is a good substrate for a reductase, which triggers ail auto-oxidative process producing reactive oxygen species and leading to juglone degradation. The degradation process continues to completion by means of a direct, presumably non-catalysed reaction with hydrogen peroxide.
File in questo prodotto:
File Dimensione Formato  
Mycological Research (2004).pdf

Solo gestori archivio

Tipologia: versione editoriale
Dimensione 144.2 kB
Formato Adobe PDF
144.2 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/32896
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 6
social impact