The use of synthetic cannabinoid receptor agonists (SCRAs) is growing among adolescents, posing major medical and psychiatric risks. JWH-018 represents the reference compound of SCRA-containing products.

Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice

Margiani, Giulia;Castelli, Maria Paola;Pintori, Nicholas;Frau, Roberto;Ennas, Maria Grazia;Fadda, Paola;De Luca, Maria Antonietta
2022-01-01

Abstract

The use of synthetic cannabinoid receptor agonists (SCRAs) is growing among adolescents, posing major medical and psychiatric risks. JWH-018 represents the reference compound of SCRA-containing products.
Chemokines; Cytokines; GFAP; IBA-1; Neuroinflammation; Synthetic cannabinoid receptor agonist; Animals; Calcium; Calcium Carbonate; Glial Fibrillary Acidic Protein; Indoles; Interleukin-13; Interleukin-2; Male; Mice; Naphthalenes; Receptor, Cannabinoid, CB1; Cannabinoid Receptor Agonists; Chemokine CCL5
File in questo prodotto:
File Dimensione Formato  
margiani_psychopharmacol_2022.pdf

accesso aperto

Tipologia: versione editoriale
Dimensione 5.46 MB
Formato Adobe PDF
5.46 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/345215
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact