Predictive value of bubble sign for tubal patency during office hysteroscopy

Objective: Our purpose was to investigate the predictive value of visible air bubble sign for real tubal patency during hysteroscopic procedures. Methods: In this cross-sectional study, clinical data of 61 infertile women who underwent diagnostic hysteroscopy and laparoscopy have been analysed. Results: Mean age of patients was 33.45 ± 3.25 years. Bubble sign for the detection of patency demonstrated 73 % (95 % CI: 57-86 %) sensitivity, 70 % (95 % CI: 46-88 %) specificity, a positive predictive value of 83 % (95 % CI: 67-94 %), and a negative predictive value of 56 % (95 % CI: 35-76 %). Conclusions: A visible tubal "flow" of air bubbles during hysteroscopy was not accurate in the prediction of tubal patency.