Morphine (0.5 mg/kg s.c.) and amphetamine (1 mg/kg s.c.) used in a two-compartment place preference test induced strong place preference when paired to the non-preferred environments. They did not modify preference under basal conditions but completely reversed morphine- and amphetamine-induced place preference. Pairing of haloperidol (0.2 mg/kg s.c.) to both environments also abolished the morphine-induced place preference.

Blockade of D-1 receptors by SCH 23390 antagonizes morphine- and amphetamine-induced place preference conditioning.

DI CHIARA, GAETANO
1987-01-01

Abstract

Morphine (0.5 mg/kg s.c.) and amphetamine (1 mg/kg s.c.) used in a two-compartment place preference test induced strong place preference when paired to the non-preferred environments. They did not modify preference under basal conditions but completely reversed morphine- and amphetamine-induced place preference. Pairing of haloperidol (0.2 mg/kg s.c.) to both environments also abolished the morphine-induced place preference.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/36263
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